Genomic Location: :...
NR annotation: GFU30528.1, sarcosine dehydrogenase, mitochondrial [Trichonephila clavipes]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q64380 | Sarcosine dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Sardh PE=1 SV=2 | ||||
| Q9UL12 | Sarcosine dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=SARDH PE=1 SV=1 | ||||
| Q99LB7 | Sarcosine dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Sardh PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01565 | FAD_binding_4 | FAD binding domain | Domain | Interproscan |
| PF01266 | DAO | FAD dependent oxidoreductase | Domain | Interproscan |
| PF00878 | CIMR | Cation-independent mannose-6-phosphate receptor repeat | Family | Interproscan |
| PF09588 | YqaJ | YqaJ-like viral recombinase domain | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF00619 | CARD | Caspase recruitment domain | Domain | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| PF08502 | LeuA_dimer | LeuA allosteric (dimerisation) domain | Domain | Interproscan |
| PF00682 | HMGL-like | HMGL-like | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036318 | Homologous_superfamily | FAD-binding, type PCMH-like superfamily | Interproscan |
| IPR036188 | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR016167 | Homologous_superfamily | FAD-binding, type PCMH, subdomain 1 | Interproscan |
| IPR016166 | Domain | FAD-binding domain, PCMH-type | Interproscan |
| IPR006094 | Domain | FAD linked oxidase, N-terminal | Interproscan |
| IPR016169 | Homologous_superfamily | FAD-binding, type PCMH, subdomain 2 | Interproscan |
| IPR050416 | Family | FAD-linked Oxidoreductases in Biosynthetic Pathways | Interproscan |
| IPR006076 | Domain | FAD dependent oxidoreductase | Interproscan |
| IPR009011 | Homologous_superfamily | Mannose-6-phosphate receptor binding domain superfamily | Interproscan |
| IPR044865 | Domain | MRH domain | Interproscan |
| IPR000479 | Repeat | Cation-independent mannose-6-phosphate receptor repeat | Interproscan |
| IPR019080 | Domain | YqaJ viral recombinase | Interproscan |
| IPR011604 | Homologous_superfamily | PD-(D/E)XK endonuclease-like domain superfamily | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR036373 | Homologous_superfamily | Large ribosomal subunit protein bL17 superfamily | Interproscan |
| IPR005550 | Family | Kinetochore protein Ndc80 | Interproscan |
| IPR033238 | Family | B-cell lymphoma/leukemia 10/E10 | Interproscan |
| IPR001315 | Domain | CARD domain | Interproscan |
| IPR011029 | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR037590 | Family | GATOR2 complex protein WDR24 | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR036230 | Homologous_superfamily | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily | Interproscan |
| IPR000891 | Domain | Pyruvate carboxyltransferase | Interproscan |
| IPR002034 | Conserved_site | Alpha-isopropylmalate/homocitrate synthase, conserved site | Interproscan |
| IPR005668 | Family | 2-isopropylmalate synthase | Interproscan |
| IPR013785 | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| IPR013709 | Domain | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | Interproscan |
| IPR039371 | Domain | LeuA, N-terminal catalytic TIM barrel domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42973 | BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED | Interproscan |
| PTHR15071 | MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER | Interproscan |
| PTHR19446 | REVERSE TRANSCRIPTASES | Interproscan |
| PTHR10643 | KINETOCHORE PROTEIN NDC80 | Interproscan |
| PTHR34920 | B-CELL LYMPHOMA/LEUKEMIA 10 | Interproscan |
| PTHR46200 | GATOR COMPLEX PROTEIN WDR24 | Interproscan |
| PTHR46911 | - | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| GO:0005537 | Molecular Function | D-mannose binding | Interproscan |
| GO:0007041 | Biological Process | lysosomal transport | Interproscan |
| GO:0038023 | Molecular Function | signaling receptor activity | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003735 | Molecular Function | structural constituent of ribosome | Interproscan |
| GO:0005840 | Cellular Component | ribosome | Interproscan |
| GO:0006412 | Biological Process | translation | Interproscan |
| GO:0031262 | Cellular Component | Ndc80 complex | Interproscan |
| GO:0051315 | Biological Process | attachment of mitotic spindle microtubules to kinetochore | Interproscan |
| GO:0002250 | Biological Process | adaptive immune response | Interproscan |
| GO:0003713 | Molecular Function | transcription coactivator activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006915 | Biological Process | apoptotic process | Interproscan |
| GO:0007249 | Biological Process | canonical NF-kappaB signal transduction | Interproscan |
| GO:0019209 | Molecular Function | kinase activator activity | Interproscan |
| GO:0032449 | Cellular Component | CBM complex | Interproscan |
| GO:0043422 | Molecular Function | protein kinase B binding | Interproscan |
| GO:0051059 | Molecular Function | NF-kappaB binding | Interproscan |
| GO:0051092 | Biological Process | positive regulation of NF-kappaB transcription factor activity | Interproscan |
| GO:2001238 | Biological Process | positive regulation of extrinsic apoptotic signaling pathway | Interproscan |
| GO:0042981 | Biological Process | regulation of apoptotic process | Interproscan |
| GO:0005774 | Cellular Component | vacuolar membrane | Interproscan |
| GO:0016239 | Biological Process | positive regulation of macroautophagy | Interproscan |
| GO:0032008 | Biological Process | positive regulation of TOR signaling | Interproscan |
| GO:0034198 | Biological Process | cellular response to amino acid starvation | Interproscan |
| GO:0061700 | Cellular Component | GATOR2 complex | Interproscan |
| GO:1904263 | Biological Process | positive regulation of TORC1 signaling | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0019752 | Biological Process | carboxylic acid metabolic process | Interproscan |
| GO:0046912 | Molecular Function | acyltransferase activity, acyl groups converted into alkyl on transfer | Interproscan |
| GO:0003852 | Molecular Function | 2-isopropylmalate synthase activity | Interproscan |
| GO:0009098 | Biological Process | L-leucine biosynthetic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01649 | leuA, IMS; 2-isopropylmalate synthase | EC:2.3.3.13 | Tuberculosis | ko05152 | deepkoala |
| Valine, leucine and isoleucine biosynthesis | ko00290 | deepkoala |