Genomic Location: :...
NR annotation: XP_020915984.1, isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial [Exaiptasia diaphana]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9VWH4 | Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Idh3a PE=2 SV=1 |
| Q9D6R2 | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Mus musculus OX=10090 GN=Idh3a PE=1 SV=1 |
| P50213 | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05380 | Peptidase_A17 | Pao retrotransposon peptidase | Family | Interproscan |
| PF00071 | Ras | Ras family | Domain | Interproscan |
| PF00180 | Iso_dh | Isocitrate/isopropylmalate dehydrogenase | Domain | Interproscan |
| PF01549 | ShK | ShK domain-like | Domain | Interproscan |
| PF13621 | Cupin_8 | Cupin-like domain | Domain | Interproscan |
| PF00080 | Sod_Cu | Copper/zinc superoxide dismutase (SODC) | Domain | Interproscan |
| PF01094 | ANF_receptor | Receptor family ligand binding region | Family | Interproscan |
| PF00003 | 7tm_3 | 7 transmembrane sweet-taste receptor of 3 GCPR | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR008042 | Family | Retrotransposon, Pao | Interproscan |
| IPR001806 | Family | Small GTPase | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR019818 | Conserved_site | Isocitrate/isopropylmalate dehydrogenase, conserved site | Interproscan |
| IPR024084 | Domain | Isopropylmalate dehydrogenase-like domain | Interproscan |
| IPR004434 | Family | Isocitrate dehydrogenase NAD-dependent | Interproscan |
| IPR003582 | Domain | ShKT domain | Interproscan |
| IPR003347 | Domain | JmjC domain | Interproscan |
| IPR014710 | Homologous_superfamily | RmlC-like jelly roll fold | Interproscan |
| IPR041667 | Domain | Cupin-like domain 8 | Interproscan |
| IPR036423 | Homologous_superfamily | Superoxide dismutase-like, copper/zinc binding domain superfamily | Interproscan |
| IPR001424 | Domain | Superoxide dismutase, copper/zinc binding domain | Interproscan |
| IPR024134 | Family | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone | Interproscan |
| IPR037524 | Domain | PA14/GLEYA domain | Interproscan |
| IPR001828 | Domain | Receptor, ligand binding region | Interproscan |
| IPR017978 | Domain | GPCR family 3, C-terminal | Interproscan |
| IPR028082 | Homologous_superfamily | Periplasmic binding protein-like I | Interproscan |
| IPR038550 | Homologous_superfamily | GPCR, family 3, nine cysteines domain superfamily | Interproscan |
| IPR050726 | Family | Metabotropic Glutamate Receptor | Interproscan |
| IPR000337 | Family | GPCR, family 3 | Interproscan |
| IPR007110 | Domain | Immunoglobulin-like domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22955 | RETROTRANSPOSON | Interproscan |
| PTHR11835 | DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE | Interproscan |
| PTHR12461 | HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED | Interproscan |
| PTHR10003 | SUPEROXIDE DISMUTASE CU-ZN -RELATED | Interproscan |
| PTHR24060 | METABOTROPIC GLUTAMATE RECEPTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0004449 | Molecular Function | isocitrate dehydrogenase (NAD+) activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006099 | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0006102 | Biological Process | isocitrate metabolic process | Interproscan |
| GO:0016706 | Molecular Function | 2-oxoglutarate-dependent dioxygenase activity | Interproscan |
| GO:0006801 | Biological Process | superoxide metabolic process | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0005507 | Molecular Function | copper ion binding | Interproscan |
| GO:0016532 | Molecular Function | superoxide dismutase copper chaperone activity | Interproscan |
| GO:0004930 | Molecular Function | G protein-coupled receptor activity | Interproscan |
| GO:0007186 | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0001640 | Molecular Function | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0007216 | Biological Process | G protein-coupled glutamate receptor signaling pathway | Interproscan |
| GO:0051966 | Biological Process | regulation of synaptic transmission, glutamatergic | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K19219 | JMJD7; peptidyl-lysine (3S)-dioxygenase / protease | EC:1.14.11.63 EC:3.4.-.- | Pathways of neurodegeneration - multiple diseases | ko05022 | deepkoala |
| Chromosome and associated proteins | ko03036 | deepkoala |