Genomic Location: :...
NR annotation: XP_044171551.1, proteasome activator complex subunit 4-like [Acropora millepora]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q14997 | Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4 PE=1 SV=2 | ||||
| F1MKX4 | Proteasome activator complex subunit 4 OS=Bos taurus OX=9913 GN=PSME4 PE=1 SV=1 | ||||
| F1QFR9 | Proteasome activator complex subunit 4A OS=Danio rerio OX=7955 GN=psme4a PE=3 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|DCUN1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03476 | MOSC_N | MOSC N-terminal beta barrel domain | Domain | Interproscan |
| PF11919 | DUF3437 | Domain of unknown function (DUF3437) | Family | Interproscan |
| PF16507 | BLM10_mid | Proteasome-substrate-size regulator, mid region | Family | Interproscan |
| PF00009 | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| PF00177 | Ribosomal_S7 | Ribosomal protein S7p/S5e | Domain | Interproscan |
| PF03143 | GTP_EFTU_D3 | Elongation factor Tu C-terminal domain | Domain | Interproscan |
| PF03144 | GTP_EFTU_D2 | Elongation factor Tu domain 2 | Domain | Interproscan |
| PF14555 | UBA_4 | UBA-like domain | Domain | Interproscan |
| PF03556 | Cullin_binding | Cullin binding | Family | Interproscan |
| PF02383 | Syja_N | SacI homology domain | Family | Interproscan |
| PF01390 | SEA | SEA domain | Family | Interproscan |
| PF01825 | GPS | GPCR proteolysis site, GPS, motif | Motif | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005303 | Domain | Molybdenum cofactor sulfurase, middle domain | Interproscan |
| IPR035309 | Family | Proteasome activator complex subunit 4 | Interproscan |
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR021843 | Domain | Proteasome activator complex subunit 4 C-terminal domain | Interproscan |
| IPR032430 | Domain | Proteasome activator Blm10, mid region | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR005717 | Family | Small ribosomal subunit protein uS7, bacterial/organellar-type | Interproscan |
| IPR004541 | Family | Translation elongation factor EFTu/EF1A, bacterial/organelle | Interproscan |
| IPR005225 | Domain | Small GTP-binding protein domain | Interproscan |
| IPR020606 | Conserved_site | Small ribosomal subunit protein uS7, conserved site | Interproscan |
| IPR000795 | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR023798 | Domain | Small ribosomal subunit protein uS7 domain | Interproscan |
| IPR031157 | Conserved_site | Tr-type G domain, conserved site | Interproscan |
| IPR033720 | Domain | Elongation factor Tu, domain 2 | Interproscan |
| IPR050055 | Family | Elongation factor Tu GTPase | Interproscan |
| IPR036823 | Homologous_superfamily | Small ribosomal subunit protein uS7 domain superfamily | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR004160 | Domain | Translation elongation factor EFTu/EF1A, C-terminal | Interproscan |
| IPR009000 | Homologous_superfamily | Translation protein, beta-barrel domain superfamily | Interproscan |
| IPR041709 | Domain | Elongation factor Tu (EF-Tu), GTP-binding domain | Interproscan |
| IPR009001 | Homologous_superfamily | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Interproscan |
| IPR004161 | Domain | Translation elongation factor EFTu-like, domain 2 | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR007527 | Domain | Zinc finger, SWIM-type | Interproscan |
| IPR014009 | Domain | PIK-related kinase | Interproscan |
| IPR038980 | Family | Serine/threonine-protein kinase ATM, plant | Interproscan |
| IPR042460 | Homologous_superfamily | DCN1-like, PONY binding domain | Interproscan |
| IPR009060 | Homologous_superfamily | UBA-like superfamily | Interproscan |
| IPR005176 | Domain | Potentiating neddylation domain | Interproscan |
| IPR014764 | Family | Defective-in-cullin neddylation protein | Interproscan |
| IPR002013 | Domain | SAC domain | Interproscan |
| IPR043573 | Family | Polyphosphoinositide phosphatase Fig4-like | Interproscan |
| IPR000082 | Domain | SEA domain | Interproscan |
| IPR036364 | Homologous_superfamily | SEA domain superfamily | Interproscan |
| IPR046338 | Homologous_superfamily | GAIN domain superfamily | Interproscan |
| IPR000203 | Conserved_site | GPS motif | Interproscan |
| IPR029865 | Family | Dyslexia-associated protein KIAA0319-like | Interproscan |
| IPR037213 | Homologous_superfamily | RUN domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR32170 | PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 | Interproscan |
| PTHR43721 | ELONGATION FACTOR TU-RELATED | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR37079 | SERINE/THREONINE-PROTEIN KINASE ATM | Interproscan |
| PTHR31511 | PROTEIN CBG23764 | Interproscan |
| PTHR12281 | RP42 RELATED | Interproscan |
| PTHR45738 | POLYPHOSPHOINOSITIDE PHOSPHATASE | Interproscan |
| PTHR46182 | FI19480P1 | Interproscan |
| PTHR46753 | FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0010499 | Biological Process | proteasomal ubiquitin-independent protein catabolic process | Interproscan |
| GO:0016504 | Molecular Function | peptidase activator activity | Interproscan |
| GO:0070577 | Molecular Function | lysine-acetylated histone binding | Interproscan |
| GO:0070628 | Molecular Function | proteasome binding | Interproscan |
| GO:0003735 | Molecular Function | structural constituent of ribosome | Interproscan |
| GO:0006412 | Biological Process | translation | Interproscan |
| GO:0015935 | Cellular Component | small ribosomal subunit | Interproscan |
| GO:0003746 | Molecular Function | translation elongation factor activity | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0006414 | Biological Process | translational elongation | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0006974 | Biological Process | DNA damage response | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000151 | Cellular Component | ubiquitin ligase complex | Interproscan |
| GO:0031624 | Molecular Function | ubiquitin conjugating enzyme binding | Interproscan |
| GO:0032182 | Molecular Function | ubiquitin-like protein binding | Interproscan |
| GO:0045116 | Biological Process | protein neddylation | Interproscan |
| GO:0097602 | Molecular Function | cullin family protein binding | Interproscan |
| GO:0016791 | Molecular Function | phosphatase activity | Interproscan |
| GO:0043231 | Cellular Component | intracellular membrane-bounded organelle | Interproscan |
| GO:0043813 | Molecular Function | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity | Interproscan |
| GO:0046856 | Biological Process | phosphatidylinositol dephosphorylation | Interproscan |
| GO:0001764 | Biological Process | neuron migration | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0031410 | Cellular Component | cytoplasmic vesicle | Interproscan |
| GO:0005764 | Cellular Component | lysosome | Interproscan |
| GO:0005770 | Cellular Component | late endosome | Interproscan |
| GO:0005776 | Cellular Component | autophagosome | Interproscan |
| GO:0072383 | Biological Process | plus-end-directed vesicle transport along microtubule | Interproscan |
| GO:1901098 | Biological Process | positive regulation of autophagosome maturation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K02358 | tuf, TUFM; elongation factor Tu | - | Proteasome | ko03051 | deepkoala |
| Pathways of neurodegeneration - multiple diseases | ko05022 | deepkoala | |||
| Ubiquitin system | ko04121 | deepkoala | |||
| Exosome | ko04147 | deepkoala |