Gene detail

Detailed information of g14374.t1 in Montipora capitata

Genomic Location: Sc0000526:60302...75078
NR annotation: XP_029201722.2, serine/threonine-protein kinase PLK4-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g14374.t1

atgacttctcgattcatgggcgactccatagaggatttccaagttctggaagtagtaggcaagggtggctttgcatgtgtgtaccgtgccagttgcatatcaacaggacaagaagttgccatcaaaatgattgacaagaagggcatgagaacatcaggattggtggcaagggtacgaaacgaagttgaaattcactgccaacttaaacatccttctattcttgagctttataactactttgaagatgcaaactatgtctaccttatccttgaaatgtgccacaatggagaagtcaatcgatacctcaagaaaactggacgaccagtcagtgaaaatcaggctcgtcatatcatgacccaagtggtcaaaggtgttctgtatcttcattcgcatggcattattcatcgagatctaaccttgggaaacattctcttgacaagtggaatggatgctaaaattggtgattttggccttgcagcaagactgtcgatgcctaatgagaagcactacactatgtgtggaaccccaaactacatttcaccggaaatagccacaagaggtcctcatggcctagagtctgacgtctggtcactgggctgcatgctctacactctactcgttggaaaacctccttttgacacagaagcagtgaaaagcaccttaaacagagtagttttagctgattatgatttaccaagtaatctttcaacagaggcccaggatcttatcacaaatttgttgaagaagaatccaggagacagaattaccctttcagggatcttagatcatccgtttatgacccaggaaagactattaaagtattcatcaacaggtcatctgtatcttcgacagaatgttgtcgagcagtcagttgacagtggaactggtaccatagcaactgtatcaacaggccttggtacaagtagatcatcgaggtcaaattttggtaaagcgggtgatcacaaaaaatctttggactctcaagcagatgatgaagtttttatcactgtatcttctgaccatcattctgatgtctggccaagacacagccatggacagcacccgccctctccacccgttagacaacgagcaagccacattgacagaaccagcacctcaaatcacaataccacctctgctaaagatatgattagaggaacagaagtggctccacctccttcctcaacctttaagcaggctacaaactctgcatcatggcttactaacattaccagctccacctttggaaacaaaccagcaaaaggcttggaaatgcctagtggtggaaacaacctcattaccaaattcaagaattacaatgctagcaaatatagcagttcctttggtaacaccttgggtgacttcctcaagaatcctaccactggcacaaacactagcagcagtggctttggcagtgcagaaatgcaattgggtcaacaggaaggtggctacccatcgactgcctcagatcttagtcatcacagttttagcgagcagactcctactgaggtcagcaagtctggttttaaggagacagttgaggatcacagagaacatcggcgccatgacagcaatagtgtttcaaaagactctggtttggatttttctcatgttaaagacggcaatgcaccaagaaagcatgaggaacaatgcaaagcaaatcagcgtagcaaatatgaggcttcaagatcaaagtctctaggagacattgtcgaacctttgaactctgaaaggttgcggccaatcaggcaaaagactagaaatgctgttgtcagtattcttgataacggagaggttgctttagagttttttcatcataaaaatggagaggacagagtttttgaggttctgcgaatatcacaaaatgggatgaaaatagcagtgtatcagccaaatggaaagggaggggtaccactctcgcaacaaccccctcctatagggtgtgagtcagcctgtacatacctgttttccaacttgccgtctagatactggaagaagtatcagtatgctactagatttgttcatctggttcgcaagaagacaccaaaggtgacaatgtactccaagcatgcaaagtgcatgttaatggaaaattttccacatgctgactttgaagtttgcttttataatggggccaaagttcatcagtcgcaggaatgcacaaggataattgaacctggtggagtatcatacacattggaatcagttggtggcctggatggcgtcactcaagaaatgaaacccctattggagcatgctcaaagttgttatcaacggtgtgctcatctggagaaagtcattaataaagaagagagtgagagttgtggaggtcgctacttcccctttgttgtgtgtcgtaaaccaccagtttcaagaaacaggtcgctgaaagaaagcactgatcaccctcaggcgcacaatccaaggccccctgaatccctagagaatttaacagtgacttcgccaagtacagtagcacccgtcagtacatcgttactctcatttgaaggaactatgaatagtgctatccaaaatatgagaccatcttcaactggcaaaggtcgtgatcctcacagaaggtcacggtcttctggagatgaatctgatgcaaagccaagaccacattcagggccagagaaaagagaacaggggaaccagcttatcaatataagtggggcccaacaaggagccttgtcatcaccatcatcacatgtcatcaagagtgtgtttgtgcaaggagtgggatgggcctcccagctgtcaacaggagaagtgtgggttcagtataatgatggatctcagatggtggttcagtcatctgtgacaagtatcaagtatacagacagttacggaacgataacaagatacagtcactctgacagattgcctgaaccaatcaaggacaagctctcttgccttcctgtcatcatagaaagtctagtggcctcacctaagatggtgtcataa

Transcript

g14374.t1

ATGACTTCTCGATTCATGGGCGACTCCATAGAGGATTTCCAAGTTCTGGAAGTAGTAGGCAAGGGTGGCTTTGCATGTGTGTACCGTGCCAGTTGCATATCAACAGGACAAGAAGTTGCCATCAAAATGatTGACAAGAAGGGCATGAGAACATCAGGATTGGTGGCAAGGGTACGAAACGAAGTTGAAATTCACTGCCAACTTAAACATCCTTCTATTCTTGAGCTTTATAACTACTTTGAAGATGCAAACTATGTCTACCTTATCCTTGAAATGTGCCACAATGGAGAAGTCAATCGATACCTCAAGAAAACTGGACGACCAGTCAGTGAAAATCAGGCTCGTCATATCATGACCCAAGTGGTCAAAGGTGTTCTGTATCTTCATTCGCATGGCATTATTCATCGAGATCTAACCTTGGGAAACATTCTCTTGACAAGTGGAATGGATGCTAAAATTGGTGATTTTGGCCTTGCAGCAAGACTGTCGATGCCTAATGAGAAGCACTACACTATGTGTGGAACCCCAAACTACATTTCACCGGAAATAGCCACAAGAGGTCCTCATGGCCTAGAGTCTGACGTCTGGTCACTGGGCTGCATGCTCTACACTCTACTCGTTGGAAAACCTCCTTTTGACaCAGAAGCAGTGAAAAGCACCTTAAACAGAGTAGTTTTAGCTGATTATGATTTACCAAGTAATCTTTCAACAGAGGCCCAGGATCTTATCACAAATTTGTTGAAGAAGAATCCAGGAGACAGAATTACCCTTTCAGGGATCTTAGATCATCCGTTTATGACCCAGGAAAGACTATTAAAGTATTCATCAACAGGTCATCTGTATCTTCGACAGAATGTTGTCGAGCAGTCAGTTGACAGTGGAACTGGTACCATAGCAACTGTATCAACAGGCCTTGGTACAAGTAGATCATCGAGGTCAAATTTTGGTAAAGCGGGTGATCACAAAAAATCTTTGGACTCTCAAGCAGATGATGAAGTTTTTATCACTGTATCTTCTGACCATCATTCTGATGTCTGGCCAAGACACAGCCATGGACAGCACCCGCCCTCTCCACCCGTTAGACAACGAGCAAGcCACATTGACAGAACCAGCACCTCAAATCACAATACCACCTCTGCTAAAGATATGATTAGAGGAACAGAAGTGGCTCCACCTCCTTCCTCAACCTTTAAGCAGGCTACAAACTCTGCATCATGGCTTACTAACATTACCAGCTCCACCTTTggaaacaaaccagcaaaaggctTGGAAATGCCTAGTGGTGGAAACAACCTCATTACCAAATTCAAgAATTACAATGCTAGCAAATATAGCAGTTCCTTTGGTAACACCTTGGGTGACTTCCTCAAGAATCCTACCACTGGCACAAACACTAGCAGCAGTGGCTTTGGCAGTGCAGAAATGCAATTGGGTCAACAGGAAGGTGGCTACCCATCGACTGCCTCAGATCTTAGTCATCACAGTTTTAGCGAGCAGACTCCTACTGAGGTCAGCAAGTCTGGTTTTAAGGAGACAGTTGAGGATCACAGAGAACATCGGCGCCATGACAGCAATAGTGTTTCAAAAGACTCTGGTTTGGATTTTTCTCATGTTAAAGACGGCAATGCACCAAGAAAGCATGAGGAACAATGCAAAGCAAATCAGCGTAGCAAATATGAGGCTTCAAGATCAAAGTCTCTAGGAGACATTGTCGAACCTTTGAACTCTGAAAGGTTGCGGCCAATCAGGCAAAAGACTAGAAATGCTGTTGTCAGTATTCTTGATAACGGAGAGGTTGCTTTAGAGTTTTTTCATCATAAAAATGGAGAGGACAGAGTTTTTGAGGTTCTGCGAATATCACAAAATGGGATGAAAATAGCAGTGTATCAGCCAAATGGAAAGGGAGGGGTACCACTCTCGCAACAACCCCCTCCTATAGGGTGTGAGTCAGCCTGTACATACCTGTTTTCCAACTTGCCGTCTAGATACTGGAAGAAGTATCAGTATGCTACTAGATTTGTTCATCTGGTTCGCAAGAAGACACCAAAGgtGACAATGTACTCCAAGCATGCAAAGTGCATGTTAATGGAAAATTTTCCACATGCTGACTTTGAAGTTTGCTTTTATAATGGGGCCAAAGTTCATCAGTCGCAGGAATGCACAAGGATAATTGAACCTGGTGGAGTATCATACACATTGGAATCAGTTGGTGGCCTGGATGGCGTCACTCAAGAAATGAAACCCCTATTGGAGCATGCTCAAAGTTGTTATCAACGGTGTGCTCATCTGGAGAAAGTCATTAATAAAGAAGAGAGTGAGAGTTGTGGAGGTCGCTACTTCCCCTTTGTTGTGTGTCGTAAACCACCAGTTTCAAGAAACAGGTCGCTGAAAGAAAGCACTGATCACCCTCAGGCGCACAATCCAAGGCCCCCTGAATCCCTAGAGAATTTAACAGTGACTTCGCCAAGTACAGTAGCACCCGTCAGTACATCGTTACTCTCATTTGAAGGAACTATGAATAGTGCTATCCAAAATATGAGACCATCTTCAACTGGCAAAGGTCGTGATCCTCACAGAAGGTCACGGTCTTCTGGAGATGAATCTGATGCAAAGCCAAGACCACATTCAGGGCCAGAGAAAAGAGAACAGGGGAACCAGCTTATCAATATAAGTGGGGCCCAACAAGGAGCCttgtcatcaccatcatcacaTGTCATCAAGAGTGTGTTTGTGCAAGGAGTGGGATGGGCCTCCCAGCTGTCAACAGGAGAAGTGTGGGTTCAGTATAATGATGGATCTCAGATGGTGGTTCAGTCATCTGTGACAAGTATCAAGTATACAGACAGTTACGGAACGATAACAAGATACAGTCACTCTGACAGATTGCCTGAACCAATCAAGGACAAGCTCTCTTGCCTTCCTGTCATCATAGAAAGTCTAGTGGCCTCACCTAAGATGGTGTCATAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A7SNN5	Serine/threonine-protein kinase PLK4 OS=Nematostella vectensis OX=45351 GN=v1g246408 PE=3 SV=1
Q6PAD2	Serine/threonine-protein kinase PLK4 OS=Xenopus laevis OX=8355 GN=plk4 PE=2 SV=1
B3DL84	Serine/threonine-protein kinase PLK4 OS=Xenopus tropicalis OX=8364 GN=plk4 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005533 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18190 all species →	Plk4_PB1	Polo-like Kinase 4 Polo Box 1	Domain	Interproscan
PF18409 all species →	Plk4_PB2	Polo-like Kinase 4 Polo Box 2	Domain	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR046437 all species →	Homologous_superfamily	Serine/threonine-protein kinase, first cryptic polo-box domain superfamily	Interproscan
IPR033699 all species →	Domain	Plk4, first cryptic polo-box domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR033698 all species →	Domain	Plk4, second cryptic polo-box domain	Interproscan
IPR047108 all species →	Homologous_superfamily	Plk4-like, second cryptic polo-box domain superfamily	Interproscan
IPR000959 all species →	Domain	POLO box domain	Interproscan
IPR033696 all species →	Domain	Plk4, C-terminal polo-box domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24345 all species →	SERINE/THREONINE-PROTEIN KINASE PLK	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000776 all species →	Cellular Component	kinetochore	Interproscan
GO:0000922 all species →	Cellular Component	spindle pole	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005813 all species →	Cellular Component	centrosome	Interproscan
GO:0007052 all species →	Biological Process	mitotic spindle organization	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08863	PLK4; polo-like kinase 4	EC:2.7.11.21	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g14374.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

48TPM > 0

3Conditions

291.8Max TPM

146.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	21	139.71	291.80
whole organisms · low pH treatment	15	15	155.45	282.29
whole organisms · extra low pH treatment pH treatment	12	12	145.64	282.30

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	291.80
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	275.49
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	240.76
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	211.92
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	201.23
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	199.96
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	195.98
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	194.98
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	187.31
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	186.48
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	178.02
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	121.52
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	108.47
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	104.77
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	74.90
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	60.73
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	37.25
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	28.14
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	12.27
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	12.15
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	9.80
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	282.29
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	254.48
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	233.33
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	227.46
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	209.32
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	206.68
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	195.76
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	188.07
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	167.30
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	117.74
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	113.59
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	102.89
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	11.74
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	11.15
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	9.87
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	282.30
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	260.25
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	215.42
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	201.06
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	188.15
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	167.01
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	155.56
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	120.40
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	118.21
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	13.72
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	13.33
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	12.19

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.