Detailed information of g1484.t1 in Montipora capitata

Genomic Location: Sc0000018:1057190...1081128
NR annotation: XP_044164302.1, LOW QUALITY PROTEIN: serine/threonine-protein kinase MAK-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q62726Serine/threonine-protein kinase ICK OS=Rattus norvegicus OX=10116 GN=Cilk1 PE=1 SV=1
Q9JKV2Serine/threonine-protein kinase ICK OS=Mus musculus OX=10090 GN=Cilk1 PE=1 SV=2
Q9UPZ9Serine/threonine-protein kinase ICK OS=Homo sapiens OX=9606 GN=CILK1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006428 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00069
all species →		PkinaseProtein kinase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000719
all species →		DomainProtein kinase domainInterproscan
IPR017441
all species →		Binding_siteProtein kinase, ATP binding siteInterproscan
IPR050117
all species →		FamilyMitogen-activated protein kinaseInterproscan
IPR008271
all species →		Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR011009
all species →		Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR24055
all species →		MITOGEN-ACTIVATED PROTEIN KINASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004672
all species →		Molecular Functionprotein kinase activityInterproscan
GO:0005524
all species →		Molecular FunctionATP bindingInterproscan
GO:0006468
all species →		Biological Processprotein phosphorylationInterproscan
GO:0004674
all species →		Molecular Functionprotein serine/threonine kinase activityInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0005929
all species →		Cellular ComponentciliumInterproscan
GO:0035556
all species →		Biological Processintracellular signal transductionInterproscan
GO:0042073
all species →		Biological Processintraciliary transportInterproscan
GO:0060271
all species →		Biological Processcilium assemblyInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for g1484.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g1484.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
197.8Max TPM
57.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 57.92 197.78
whole organisms · low pH treatment 15 15 52.10 163.07
whole organisms · extra low pH treatment pH treatment 12 12 63.06 185.13

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 197.78
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 166.67
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 155.94
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 85.35
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 84.76
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 76.12
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 71.51
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 51.41
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 35.77
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 33.57
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 30.43
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 27.14
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 26.08
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 23.87
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 23.27
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 23.07
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 22.69
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 22.50
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 22.10
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 21.34
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 14.96
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 163.07
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 162.56
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 148.31
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 36.41
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 36.35
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 32.05
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 28.99
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 28.06
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 26.47
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 26.19
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 20.64
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 19.99
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 19.40
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 17.26
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 15.71
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 185.13
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 173.24
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 166.81
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 36.02
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 31.66
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 30.15
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 24.89
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 24.73
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 24.10
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 21.20
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 20.74
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 17.98

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated36g343.t10.993071476974423
Negatively correlated5g6649.t1-0.929364546227929

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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