Detailed information of g14848.t1 in Montipora capitata

Genomic Location: Sc0000561:126260...135113
NR annotation: XP_029187439.1, ubiquitin thioesterase OTUB1-like isoform X1 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q96FW1Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2
Q7TQI3Ubiquitin thioesterase OTUB1 OS=Mus musculus OX=10090 GN=Otub1 PE=1 SV=2
B2RYG6Ubiquitin thioesterase OTUB1 OS=Rattus norvegicus OX=10116 GN=Otub1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006281 (this species only) · gene tree & orthology
Ubiquitin familyDUB|OTU|OTU · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF10275
all species →		Peptidase_C65Peptidase C65 OtubainFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR016615
all species →		FamilyUbiquitin thioesterase OtubainInterproscan
IPR003323
all species →		DomainOTU domainInterproscan
IPR038765
all species →		Homologous_superfamilyPapain-like cysteine peptidase superfamilyInterproscan
IPR042468
all species →		Homologous_superfamilyPeptidase C65, otubain, subdomain 1Interproscan
IPR019400
all species →		FamilyPeptidase C65, otubainInterproscan
IPR042467
all species →		Homologous_superfamilyPeptidase C65, otubain, subdomain 2Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR12931
all species →		UBIQUITIN THIOLESTERASE PROTEIN OTUBInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0016579
all species →		Biological Processprotein deubiquitinationInterproscan
GO:0016787
all species →		Molecular Functionhydrolase activityInterproscan
GO:0004843
all species →		Molecular Functioncysteine-type deubiquitinase activityInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0043130
all species →		Molecular Functionubiquitin bindingInterproscan
GO:0071108
all species →		Biological Processprotein K48-linked deubiquitinationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K09602OTUB1; ubiquitin thioesterase protein OTUB1EC:3.4.19.12
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g14848.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
1,219.3Max TPM
455.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 432.61 1,165.09
whole organisms · low pH treatment 15 15 458.86 1,219.30
whole organisms · extra low pH treatment pH treatment 12 12 490.74 1,075.63

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 1,165.09
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 892.17
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 867.39
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 836.08
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 791.55
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 719.66
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 637.11
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 596.88
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 584.72
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 528.32
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 503.53
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 193.47
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 158.48
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 141.31
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 93.56
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 91.75
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 90.18
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 57.26
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 50.16
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 43.58
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 42.58
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 1,219.30
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 849.00
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 829.64
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 732.86
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 717.92
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 565.70
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 544.71
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 465.69
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 340.02
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 165.37
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 140.76
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 127.56
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 66.17
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 61.56
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 56.64
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 1,075.63
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 891.90
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 808.63
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 786.86
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 673.18
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 627.23
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 518.80
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 176.25
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 173.29
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 62.72
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 50.69
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 43.67

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated25g7071.t10.968430543266147
Negatively correlated7g1076.t1-0.917039002783808

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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