Genomic Location: :...
NR annotation: KYO44680.1, integrin-alpha FG-GAP repeat-containing protein 2 [Alligator mississippiensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q91WI7 | KICSTOR complex protein ITFG2 OS=Mus musculus OX=10090 GN=Itfg2 PE=2 SV=1 | ||||
| Q5RBH8 | KICSTOR complex protein ITFG2 OS=Pongo abelii OX=9601 GN=ITFG2 PE=2 SV=1 | ||||
| Q969R8 | KICSTOR complex protein ITFG2 OS=Homo sapiens OX=9606 GN=ITFG2 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | P53 |
| Ubiquitin Family | UBD|Other|SH3 |
| Transcription Factors Family | TF_bZIP |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF07653 | SH3_2 | Variant SH3 domain | Domain | Interproscan |
| PF00787 | PX | PX domain | Domain | Interproscan |
| PF15907 | Itfg2 | Integrin-alpha FG-GAP repeat-containing protein 2 | Repeat | Interproscan |
| PF03366 | YEATS | YEATS family | Domain | Interproscan |
| PF01363 | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF03571 | Peptidase_M49 | Peptidase family M49 | Family | Interproscan |
| PF05699 | Dimer_Tnp_hAT | hAT family C-terminal dimerisation region | Domain | Interproscan |
| PF02996 | Prefoldin | Prefoldin subunit | Coiled-coil | Interproscan |
| PF00170 | bZIP_1 | bZIP transcription factor | Coiled-coil | Interproscan |
| PF00870 | P53 | P53 DNA-binding domain | Domain | Interproscan |
| PF07710 | P53_tetramer | P53 tetramerisation motif | Motif | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036871 | Homologous_superfamily | PX domain superfamily | Interproscan |
| IPR001683 | Domain | Phox homology | Interproscan |
| IPR051228 | Family | NADPH Oxidase and PX Domain-Containing | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR031793 | Family | Integrin-alpha FG-GAP repeat-containing protein 2 | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR005033 | Family | YEATS | Interproscan |
| IPR038704 | Homologous_superfamily | YEATS superfamily | Interproscan |
| IPR043548 | Family | 1-phosphatidylinositol-3phosphate-5-kinase | Interproscan |
| IPR000306 | Domain | FYVE zinc finger | Interproscan |
| IPR011011 | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR017455 | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR039461 | Family | Peptidase family M49 | Interproscan |
| IPR008906 | Domain | HAT, C-terminal dimerisation domain | Interproscan |
| IPR052035 | Family | Zinc finger BED domain-containing | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR016655 | Family | Prefoldin subunit 3 | Interproscan |
| IPR004127 | Family | Prefoldin alpha-like | Interproscan |
| IPR009053 | Homologous_superfamily | Prefoldin | Interproscan |
| IPR051381 | Family | cAMP-responsive element-binding ATF subfamily | Interproscan |
| IPR004827 | Domain | Basic-leucine zipper domain | Interproscan |
| IPR046347 | Homologous_superfamily | Basic-leucine zipper domain superfamily | Interproscan |
| IPR011615 | Domain | p53, DNA-binding domain | Interproscan |
| IPR008967 | Homologous_superfamily | p53-like transcription factor, DNA-binding domain superfamily | Interproscan |
| IPR012346 | Homologous_superfamily | p53/RUNT-type transcription factor, DNA-binding domain superfamily | Interproscan |
| IPR002117 | Family | p53 tumour suppressor family | Interproscan |
| IPR010991 | Domain | p53, tetramerisation domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR15706 | SH3 MULTIPLE DOMAIN | Interproscan |
| PTHR16317 | INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING | Interproscan |
| PTHR23195 | YEATS DOMAIN | Interproscan |
| PTHR46715 | 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR23422 | DIPEPTIDYL PEPTIDASE III-RELATED | Interproscan |
| PTHR46481 | ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 | Interproscan |
| PTHR12409 | PREFOLDIN SUBUNIT 3 | Interproscan |
| PTHR45996 | AGAP001464-PB | Interproscan |
| PTHR11447 | CELLULAR TUMOR ANTIGEN P53 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016176 | Molecular Function | superoxide-generating NADPH oxidase activator activity | Interproscan |
| GO:0042554 | Biological Process | superoxide anion generation | Interproscan |
| GO:0032006 | Biological Process | regulation of TOR signaling | Interproscan |
| GO:0140007 | Cellular Component | KICSTOR complex | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0006338 | Biological Process | chromatin remodeling | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0016573 | Biological Process | obsolete histone acetylation | Interproscan |
| GO:0035267 | Cellular Component | NuA4 histone acetyltransferase complex | Interproscan |
| GO:0042393 | Molecular Function | histone binding | Interproscan |
| GO:0140672 | Cellular Component | ATAC complex | Interproscan |
| GO:0000285 | Molecular Function | 1-phosphatidylinositol-3-phosphate 5-kinase activity | Interproscan |
| GO:0012506 | Cellular Component | vesicle membrane | Interproscan |
| GO:0030593 | Biological Process | neutrophil chemotaxis | Interproscan |
| GO:0031410 | Cellular Component | cytoplasmic vesicle | Interproscan |
| GO:0032438 | Biological Process | melanosome organization | Interproscan |
| GO:0052810 | Molecular Function | 1-phosphatidylinositol-5-kinase activity | Interproscan |
| GO:0090385 | Biological Process | phagosome-lysosome fusion | Interproscan |
| GO:1903426 | Biological Process | regulation of reactive oxygen species biosynthetic process | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0008239 | Molecular Function | dipeptidyl-peptidase activity | Interproscan |
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0006457 | Biological Process | protein folding | Interproscan |
| GO:0016272 | Cellular Component | prefoldin complex | Interproscan |
| GO:0005844 | Cellular Component | obsolete polysome | Interproscan |
| GO:0007017 | Biological Process | microtubule-based process | Interproscan |
| GO:0007021 | Biological Process | tubulin complex assembly | Interproscan |
| GO:0015631 | Molecular Function | tubulin binding | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0000976 | Molecular Function | transcription cis-regulatory region binding | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0006915 | Biological Process | apoptotic process | Interproscan |
| GO:0051262 | Biological Process | protein tetramerization | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K09048 | CREB3; cyclic AMP-responsive element-binding protein 3 | - | Membrane trafficking | ko04131 | deepkoala |
| DNA repair and recombination proteins | ko03400 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| Transcription factors | ko03000 | deepkoala |