Genomic Location: :...
NR annotation: XP_002166775.2, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase isoform X1 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q27312 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase OS=Aplysia kurodai OX=6501 PE=1 SV=1 |
| P29241 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase OS=Aplysia californica OX=6500 PE=1 SV=1 |
| Q10588 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 OS=Homo sapiens OX=9606 GN=BST1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08123 | DOT1 | Histone methylation protein DOT1 | Domain | Interproscan |
| PF02267 | Rib_hydrolayse | ADP-ribosyl cyclase | Domain | Interproscan |
| PF00289 | Biotin_carb_N | Biotin carboxylase, N-terminal domain | Domain | Interproscan |
| PF01400 | Astacin | Astacin (Peptidase family M12A) | Domain | Interproscan |
| PF01549 | ShK | ShK domain-like | Domain | Interproscan |
| PF00629 | MAM | MAM domain, meprin/A5/mu | Domain | Interproscan |
| PF00090 | TSP_1 | Thrombospondin type 1 domain | Domain | Interproscan |
| PF14580 | LRR_9 | Leucine-rich repeat | Repeat | Interproscan |
| PF06650 | VPS13_VAB | Vacuolar-sorting associated protein 13, adaptor binding domain | Domain | Interproscan |
| PF21679 | VPS13_C | Intermembrane lipid transfer protein VPS13, C-terminal | Domain | Interproscan |
| PF09333 | ATG2-VPS13_C | ATG2/VPS13, C terminal domain | Domain | Interproscan |
| PF16908 | VPS13_ext_chorein | Vacuolar sorting-associated protein 13, extended-chorein | Repeat | Interproscan |
| PF12624 | Chorein_N | VPS13-like, N-terminal | Domain | Interproscan |
| PF16910 | VPS13_mid_rpt | VPS13, central RBG modules | Repeat | Interproscan |
| PF16909 | VPS13_DH-like | Vacuolar-sorting-associated 13 protein, DH-like domain | Family | Interproscan |
| PF16922 | SLD5_C | DNA replication complex GINS protein SLD5 C-terminus | Domain | Interproscan |
| PF05916 | Sld5 | GINS complex protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR025789 | Domain | Histone-lysine N-methyltransferase DOT1 domain | Interproscan |
| IPR029063 | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR030445 | Family | Histone H3-K79 methyltransferase | Interproscan |
| IPR038765 | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR003193 | Family | ADP-ribosyl cyclase (CD38/157) | Interproscan |
| IPR050856 | Family | Biotin-dependent Carboxylase Complex | Interproscan |
| IPR016185 | Homologous_superfamily | Pre-ATP-grasp domain superfamily | Interproscan |
| IPR005481 | Domain | Biotin carboxylase-like, N-terminal domain | Interproscan |
| IPR011764 | Domain | Biotin carboxylation domain | Interproscan |
| IPR013320 | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR001506 | Domain | Peptidase M12A | Interproscan |
| IPR036383 | Homologous_superfamily | Thrombospondin type-1 (TSP1) repeat superfamily | Interproscan |
| IPR003582 | Domain | ShKT domain | Interproscan |
| IPR034035 | Domain | Astacin-like metallopeptidase domain | Interproscan |
| IPR000998 | Domain | MAM domain | Interproscan |
| IPR000884 | Repeat | Thrombospondin type-1 (TSP1) repeat | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR006026 | Domain | Peptidase, metallopeptidase | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR050836 | Family | SDS22/Internalin LRR-containing | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR026847 | Family | Vacuolar protein sorting-associated protein 13 | Interproscan |
| IPR009543 | Domain | Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain | Interproscan |
| IPR049424 | Domain | Intermembrane lipid transfer protein VPS13, C-terminal | Interproscan |
| IPR015412 | Domain | Atg2/VPS13, C-terminal | Interproscan |
| IPR031646 | Domain | Vacuolar protein sorting-associated protein 13, extended chorein | Interproscan |
| IPR026854 | Domain | Vacuolar protein sorting-associated protein 13-like, N-terminal domain | Interproscan |
| IPR031642 | Domain | VPS13, middle RBG modules | Interproscan |
| IPR031645 | Domain | Vacuolar protein sorting-associated protein 13, DH-like domain | Interproscan |
| IPR008591 | Family | GINS complex subunit Sld5 | Interproscan |
| IPR031633 | Domain | DNA replication complex GINS protein SLD5, C-terminal | Interproscan |
| IPR038749 | Domain | GINS complex protein Sld5, alpha-helical domain | Interproscan |
| IPR021151 | Domain | GINS subunit, domain A | Interproscan |
| IPR036224 | Homologous_superfamily | GINS, helical bundle-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21451 | HISTONE H3 METHYLTRANSFERASE | Interproscan |
| PTHR10912 | ADP-RIBOSYL CYCLASE | Interproscan |
| PTHR18866 | CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE | Interproscan |
| PTHR10127 | DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING | Interproscan |
| PTHR46652 | LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR16166 | VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 | Interproscan |
| PTHR21206 | SLD5 PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0031151 | Molecular Function | histone H3K79 methyltransferase activity | Interproscan |
| GO:0000077 | Biological Process | DNA damage checkpoint signaling | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0051726 | Biological Process | regulation of cell cycle | Interproscan |
| GO:2000677 | Biological Process | regulation of transcription regulatory region DNA binding | Interproscan |
| GO:0003953 | Molecular Function | NAD+ nucleosidase activity | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0016849 | Molecular Function | phosphorus-oxygen lyase activity | Interproscan |
| GO:0030890 | Biological Process | positive regulation of B cell proliferation | Interproscan |
| GO:0061809 | Molecular Function | NAD+ nucleotidase, cyclic ADP-ribose generating | Interproscan |
| GO:0004485 | Molecular Function | methylcrotonoyl-CoA carboxylase activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0006623 | Biological Process | protein targeting to vacuole | Interproscan |
| GO:0019898 | Cellular Component | extrinsic component of membrane | Interproscan |
| GO:0045053 | Biological Process | protein retention in Golgi apparatus | Interproscan |
| GO:0006261 | Biological Process | DNA-templated DNA replication | Interproscan |
| GO:0000727 | Biological Process | double-strand break repair via break-induced replication | Interproscan |
| GO:0000811 | Cellular Component | GINS complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10735 | GINS4, SLD5; GINS complex subunit 4 | - | Membrane trafficking | ko04131 | deepkoala |
| Choline metabolism in cancer | ko05231 | deepkoala | |||
| DNA replication proteins | ko03032 | deepkoala |