Genomic Location: :...
NR annotation: XP_013415675.1, probable E3 ubiquitin-protein ligase HERC1 [Lingula anatina]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q15751 | Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens OX=9606 GN=HERC1 PE=1 SV=2 | ||||
| Q8CFD5 | DNA excision repair protein ERCC-8 OS=Mus musculus OX=10090 GN=Ercc8 PE=1 SV=2 | ||||
| Q13216 | DNA excision repair protein ERCC-8 OS=Homo sapiens OX=9606 GN=ERCC8 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|CDC20 |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12146 | Hydrolase_4 | Serine aminopeptidase, S33 | Family | Interproscan |
| PF00676 | E1_dh | Dehydrogenase E1 component | Family | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| PF01505 | Vault | Major Vault Protein repeat domain | Domain | Interproscan |
| PF05186 | Dpy-30 | Dpy-30 motif | Motif | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR050266 | Family | AB hydrolase superfamily | Interproscan |
| IPR029058 | Homologous_superfamily | Alpha/Beta hydrolase fold | Interproscan |
| IPR022742 | Domain | Serine aminopeptidase, S33 | Interproscan |
| IPR000073 | Domain | Alpha/beta hydrolase fold-1 | Interproscan |
| IPR029061 | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR011603 | Family | 2-oxoglutarate dehydrogenase E1 component | Interproscan |
| IPR001017 | Domain | Dehydrogenase, E1 component | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR020472 | Repeat | G-protein beta WD-40 repeat | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR019775 | Conserved_site | WD40 repeat, conserved site | Interproscan |
| IPR042238 | Family | DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1 | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR002499 | Repeat | Major vault protein, N-terminal | Interproscan |
| IPR043023 | Homologous_superfamily | Major vault protein repeat domain superfamily | Interproscan |
| IPR039059 | Family | Major vault protein | Interproscan |
| IPR041139 | Domain | Major vault protein repeat domain | Interproscan |
| IPR047499 | Domain | Adenylate kinase 7, dimerization/docking domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR007858 | Conserved_site | Dpy-30 motif | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43798 | MONOACYLGLYCEROL LIPASE | Interproscan |
| PTHR23152 | 2-OXOGLUTARATE DEHYDROGENASE | Interproscan |
| PTHR46202 | DNA EXCISION REPAIR PROTEIN ERCC-8 | Interproscan |
| PTHR14165 | MAJOR VAULT PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004591 | Molecular Function | oxoglutarate dehydrogenase (succinyl-transferring) activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006099 | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0016624 | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Interproscan |
| GO:0030976 | Molecular Function | thiamine pyrophosphate binding | Interproscan |
| GO:0045252 | Cellular Component | oxoglutarate dehydrogenase complex | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000109 | Cellular Component | nucleotide-excision repair complex | Interproscan |
| GO:0000209 | Biological Process | protein polyubiquitination | Interproscan |
| GO:0006283 | Biological Process | transcription-coupled nucleotide-excision repair | Interproscan |
| GO:0031464 | Cellular Component | Cul4A-RING E3 ubiquitin ligase complex | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10570 | ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8 | - | DNA repair and recombination proteins | ko03400 | deepkoala |