Genomic Location: :...
NR annotation: XP_047139465.1, E3 ubiquitin-protein ligase NEDD4 isoform X2 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q5RBF2 | E3 ubiquitin-protein ligase NEDD4-like OS=Pongo abelii OX=9601 GN=NEDD4L PE=2 SV=1 | ||||
| Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens OX=9606 GN=NEDD4L PE=1 SV=2 | ||||
| Q8CFI0 | E3 ubiquitin-protein ligase NEDD4-like OS=Mus musculus OX=10090 GN=Nedd4l PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03061 | 4HBT | Thioesterase superfamily | Domain | Interproscan |
| PF05380 | Peptidase_A17 | Pao retrotransposon peptidase | Family | Interproscan |
| PF02272 | DHHA1 | DHHA1 domain | Family | Interproscan |
| PF07973 | tRNA_SAD | Threonyl and Alanyl tRNA synthetase second additional domain | Domain | Interproscan |
| PF01411 | tRNA-synt_2c | tRNA synthetases class II (A) | Family | Interproscan |
| PF00168 | C2 | C2 domain | Domain | Interproscan |
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00397 | WW | WW domain | Domain | Interproscan |
| PF00153 | Mito_carr | Mitochondrial carrier protein | Repeat | Interproscan |
| PF00002 | 7tm_2 | 7 transmembrane receptor (Secretin family) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033120 | Domain | Hotdog acyl-CoA thioesterase (ACOT)-type domain | Interproscan |
| IPR029069 | Homologous_superfamily | HotDog domain superfamily | Interproscan |
| IPR006683 | Domain | Thioesterase domain | Interproscan |
| IPR040170 | Family | Cytosolic acyl coenzyme A thioester hydrolase | Interproscan |
| IPR008042 | Family | Retrotransposon, Pao | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR012947 | Domain | Threonyl/alanyl tRNA synthetase, SAD | Interproscan |
| IPR003156 | Domain | DHHA1 domain | Interproscan |
| IPR018162 | Homologous_superfamily | Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily | Interproscan |
| IPR045864 | Homologous_superfamily | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Interproscan |
| IPR009000 | Homologous_superfamily | Translation protein, beta-barrel domain superfamily | Interproscan |
| IPR050058 | Family | Alanine--tRNA ligase | Interproscan |
| IPR002318 | Family | Alanine-tRNA ligase, class IIc | Interproscan |
| IPR018163 | Homologous_superfamily | Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily | Interproscan |
| IPR023033 | Family | Alanine-tRNA ligase, eukaryota/bacteria | Interproscan |
| IPR018165 | Domain | Alanyl-tRNA synthetase, class IIc, core domain | Interproscan |
| IPR018164 | Domain | Alanyl-tRNA synthetase, class IIc, N-terminal | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR001202 | Domain | WW domain | Interproscan |
| IPR000008 | Domain | C2 domain | Interproscan |
| IPR024928 | Family | E3 ubiquitin-protein ligase, SMURF1 type | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR050409 | Family | E3 ubiquitin-protein ligase | Interproscan |
| IPR023395 | Homologous_superfamily | Mitochondrial carrier domain superfamily | Interproscan |
| IPR018108 | Repeat | Mitochondrial substrate/solute carrier | Interproscan |
| IPR050567 | Family | Mitochondrial Carrier | Interproscan |
| IPR000832 | Family | GPCR, family 2, secretin-like | Interproscan |
| IPR017981 | Domain | GPCR, family 2-like, 7TM | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11049 | ACYL COENZYME A THIOESTER HYDROLASE | Interproscan |
| PTHR22955 | RETROTRANSPOSON | Interproscan |
| PTHR11777 | ALANYL-TRNA SYNTHETASE | Interproscan |
| PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | Interproscan |
| PTHR45624 | MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED | Interproscan |
| PTHR12011 | ADHESION G-PROTEIN COUPLED RECEPTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005654 | Cellular Component | nucleoplasm | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006637 | Biological Process | acyl-CoA metabolic process | Interproscan |
| GO:0016290 | Molecular Function | obsolete palmitoyl-CoA hydrolase activity | Interproscan |
| GO:0016790 | Molecular Function | thiolester hydrolase activity | Interproscan |
| GO:0047617 | Molecular Function | fatty acyl-CoA hydrolase activity | Interproscan |
| GO:0070062 | Cellular Component | extracellular exosome | Interproscan |
| GO:1900535 | Biological Process | palmitic acid biosynthetic process | Interproscan |
| GO:0004812 | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0043039 | Biological Process | tRNA aminoacylation | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0004813 | Molecular Function | alanine-tRNA ligase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0006419 | Biological Process | alanyl-tRNA aminoacylation | Interproscan |
| GO:0002161 | Molecular Function | aminoacyl-tRNA editing activity | Interproscan |
| GO:0045892 | Biological Process | negative regulation of DNA-templated transcription | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0006511 | Biological Process | ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0000209 | Biological Process | protein polyubiquitination | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0048814 | Biological Process | regulation of dendrite morphogenesis | Interproscan |
| GO:2000650 | Biological Process | negative regulation of sodium ion transmembrane transporter activity | Interproscan |
| GO:0005740 | Cellular Component | mitochondrial envelope | Interproscan |
| GO:0006810 | Biological Process | transport | Interproscan |
| GO:0006839 | Biological Process | mitochondrial transport | Interproscan |
| GO:0015227 | Molecular Function | acyl carnitine transmembrane transporter activity | Interproscan |
| GO:0022857 | Molecular Function | transmembrane transporter activity | Interproscan |
| GO:1902603 | Biological Process | carnitine transmembrane transport | Interproscan |
| GO:0004930 | Molecular Function | G protein-coupled receptor activity | Interproscan |
| GO:0007186 | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0004888 | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| GO:0007166 | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0007189 | Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01872 | AARS, alaS; alanyl-tRNA synthetase | EC:6.1.1.7 | Mitochondrial biogenesis | ko03029 | deepkoala |
| Transporters | ko02000 | deepkoala | |||
| Transfer RNA biogenesis | ko03016 | deepkoala |