Genomic Location: :...
NR annotation: XP_035694813.1, E3 ubiquitin-protein ligase SMURF2-like isoform X1 [Branchiostoma floridae]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q2TAS2 | E3 ubiquitin-protein ligase SMURF2 OS=Xenopus laevis OX=8355 GN=smurf2 PE=2 SV=1 | ||||
| Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens OX=9606 GN=SMURF2 PE=1 SV=1 | ||||
| A9JRZ0 | E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio OX=7955 GN=smurf2 PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity|HECT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00397 | WW | WW domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR050409 | Family | E3 ubiquitin-protein ligase | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR001202 | Domain | WW domain | Interproscan |
| IPR024928 | Family | E3 ubiquitin-protein ligase, SMURF1 type | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000209 | Biological Process | protein polyubiquitination | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0030514 | Biological Process | negative regulation of BMP signaling pathway | Interproscan |
| GO:0030579 | Biological Process | obsolete ubiquitin-dependent SMAD protein catabolic process | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0006511 | Biological Process | ubiquitin-dependent protein catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04678 | SMURF; E3 ubiquitin ligase SMURF1/2 | EC:2.3.2.26 | Mitochondrial biogenesis | ko03029 | deepkoala |