Genomic Location: :...
NR annotation: CAH3144812.1, unnamed protein product [Porites lobata]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| D3ZGQ5 | Serine/threonine-protein kinase Nek8 OS=Rattus norvegicus OX=10116 GN=Nek8 PE=1 SV=1 |
| Q90XC2 | Serine/threonine-protein kinase Nek8 OS=Danio rerio OX=7955 GN=nek8 PE=2 SV=1 |
| Q91ZR4 | Serine/threonine-protein kinase Nek8 OS=Mus musculus OX=10090 GN=Nek8 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00241 | Cofilin_ADF | Cofilin/tropomyosin-type actin-binding protein | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF13540 | RCC1_2 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017904 | Family | ADF/Cofilin | Interproscan |
| IPR002108 | Domain | Actin-depolymerising factor homology domain | Interproscan |
| IPR029006 | Homologous_superfamily | ADF-H/Gelsolin-like domain superfamily | Interproscan |
| IPR009091 | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR000408 | Repeat | Regulator of chromosome condensation, RCC1 | Interproscan |
| IPR017972 | Conserved_site | Cytochrome P450, conserved site | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR051997 | Family | Serine/threonine-protein kinase NEK | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR024132 | Family | Akirin | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11913 | COFILIN-RELATED | Interproscan |
| PTHR44535 | PROTEIN CBG16200 | Interproscan |
| PTHR13293 | UNCHARACTERIZED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0015629 | Cellular Component | actin cytoskeleton | Interproscan |
| GO:0030042 | Biological Process | actin filament depolymerization | Interproscan |
| GO:0030043 | Biological Process | actin filament fragmentation | Interproscan |
| GO:0030479 | Cellular Component | actin cortical patch | Interproscan |
| GO:0051014 | Biological Process | actin filament severing | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:0003779 | Molecular Function | actin binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0000785 | Cellular Component | chromatin | Interproscan |
| GO:0003712 | Molecular Function | transcription coregulator activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0045089 | Biological Process | positive regulation of innate immune response | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20877 | NEK8; serine/threonine-protein kinase Nek8 | EC:2.7.11.1 | Cilium and associated proteins | ko03037 | deepkoala |