Genomic Location: :...
NR annotation: XP_047141525.1, pre-mRNA-processing-splicing factor 8 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 | ||||
| Q99PV0 | Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2 | ||||
| P34369 | Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Alpha-Helix|GAT |
| Ubiquitin Family | UBD|Other|Jab_MPN |
| Ubiquitin Family | UBD|Alpha-Helix|VHS |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21771 | DUF6871 | Domain of unknown function (DUF6871) | Domain | Interproscan |
| PF00109 | ketoacyl-synt | Beta-ketoacyl synthase, N-terminal domain | Domain | Interproscan |
| PF02801 | Ketoacyl-synt_C | Beta-ketoacyl synthase, C-terminal domain | Domain | Interproscan |
| PF00307 | CH | Calponin homology (CH) domain | Domain | Interproscan |
| PF03184 | DDE_1 | DDE superfamily endonuclease | Family | Interproscan |
| PF18308 | GGA_N-GAT | N-terminal extension of GAT domain | Family | Interproscan |
| PF00790 | VHS | VHS domain | Repeat | Interproscan |
| PF00397 | WW | WW domain | Domain | Interproscan |
| PF01398 | JAB | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | Family | Interproscan |
| PF10597 | U5_2-snRNA_bdg | U5-snRNA binding site 2 of PrP8 | Domain | Interproscan |
| PF12134 | PRP8_domainIV | PRP8 domain IV core | Domain | Interproscan |
| PF10598 | RRM_4 | RNA recognition motif of the spliceosomal PrP8 | Domain | Interproscan |
| PF10596 | U6-snRNA_bdg | U6-snRNA interacting domain of PrP8 | Domain | Interproscan |
| PF08083 | PROCN | PROCN (NUC071) domain | Domain | Interproscan |
| PF08082 | PRO8NT | PRO8NT (NUC069), PrP8 N-terminal domain | Domain | Interproscan |
| PF01834 | XRCC1_N | XRCC1 N terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR049270 | Domain | Cilia- and flagella-associated protein 58, central coiled coil | Interproscan |
| IPR020841 | Domain | Polyketide synthase, beta-ketoacyl synthase domain | Interproscan |
| IPR014030 | Domain | Beta-ketoacyl synthase, N-terminal | Interproscan |
| IPR017568 | Family | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | Interproscan |
| IPR016039 | Homologous_superfamily | Thiolase-like | Interproscan |
| IPR000794 | Family | Beta-ketoacyl synthase | Interproscan |
| IPR018201 | Active_site | Beta-ketoacyl synthase, active site | Interproscan |
| IPR014031 | Domain | Beta-ketoacyl synthase, C-terminal | Interproscan |
| IPR001589 | Conserved_site | Actinin-type actin-binding domain, conserved site | Interproscan |
| IPR001715 | Domain | Calponin homology domain | Interproscan |
| IPR036872 | Homologous_superfamily | CH domain superfamily | Interproscan |
| IPR004875 | Domain | DDE superfamily endonuclease domain | Interproscan |
| IPR041198 | Domain | N-terminal extension of GAT domain | Interproscan |
| IPR002014 | Domain | VHS domain | Interproscan |
| IPR008942 | Homologous_superfamily | ENTH/VHS | Interproscan |
| IPR004152 | Domain | GAT domain | Interproscan |
| IPR027422 | Family | ADP-ribosylation factor-binding protein GGA1-3 | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR001202 | Domain | WW domain | Interproscan |
| IPR000555 | Domain | JAB1/MPN/MOV34 metalloenzyme domain | Interproscan |
| IPR019581 | Domain | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding | Interproscan |
| IPR042516 | Homologous_superfamily | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR027652 | Family | Pre-mRNA-processing-splicing factor 8 | Interproscan |
| IPR021983 | Domain | PRP8 domain IV core | Interproscan |
| IPR019582 | Domain | RNA recognition motif, spliceosomal PrP8 | Interproscan |
| IPR019580 | Domain | Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding | Interproscan |
| IPR012592 | Domain | PROCN domain | Interproscan |
| IPR012591 | Domain | PRO8NT domain | Interproscan |
| IPR043172 | Homologous_superfamily | Prp8 RNase domain IV, palm region | Interproscan |
| IPR043173 | Homologous_superfamily | Prp8 RNase domain IV, fingers region | Interproscan |
| IPR008979 | Homologous_superfamily | Galactose-binding-like domain superfamily | Interproscan |
| IPR013087 | Domain | Zinc finger C2H2-type | Interproscan |
| IPR002706 | Domain | DNA-repair protein Xrcc1, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR32083 | CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED | Interproscan |
| PTHR11712 | POLYKETIDE SYNTHASE-RELATED | Interproscan |
| PTHR11915 | SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN | Interproscan |
| PTHR45905 | GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN | Interproscan |
| PTHR11140 | PRE-MRNA SPLICING FACTOR PRP8 | Interproscan |
| PTHR11370 | DNA-REPAIR PROTEIN XRCC1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005856 | Cellular Component | cytoskeleton | Interproscan |
| GO:0006633 | Biological Process | fatty acid biosynthetic process | Interproscan |
| GO:0016747 | Molecular Function | acyltransferase activity, transferring groups other than amino-acyl groups | Interproscan |
| GO:0016746 | Molecular Function | acyltransferase activity | Interproscan |
| GO:0004315 | Molecular Function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0030036 | Biological Process | actin cytoskeleton organization | Interproscan |
| GO:0030054 | Cellular Component | cell junction | Interproscan |
| GO:0030864 | Cellular Component | cortical actin cytoskeleton | Interproscan |
| GO:0042995 | Cellular Component | cell projection | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0005802 | Cellular Component | trans-Golgi network | Interproscan |
| GO:0006886 | Biological Process | intracellular protein transport | Interproscan |
| GO:0006893 | Biological Process | Golgi to plasma membrane transport | Interproscan |
| GO:0031267 | Molecular Function | small GTPase binding | Interproscan |
| GO:0034394 | Biological Process | protein localization to cell surface | Interproscan |
| GO:0008233 | Molecular Function | peptidase activity | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0030623 | Molecular Function | U5 snRNA binding | Interproscan |
| GO:0000244 | Biological Process | spliceosomal tri-snRNP complex assembly | Interproscan |
| GO:0000398 | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0005681 | Cellular Component | spliceosomal complex | Interproscan |
| GO:0005682 | Cellular Component | U5 snRNP | Interproscan |
| GO:0017070 | Molecular Function | U6 snRNA binding | Interproscan |
| GO:0030619 | Molecular Function | U1 snRNA binding | Interproscan |
| GO:0030620 | Molecular Function | U2 snRNA binding | Interproscan |
| GO:0071013 | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0097157 | Molecular Function | pre-mRNA intronic binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006284 | Biological Process | base-excision repair | Interproscan |
| GO:0000012 | Biological Process | single strand break repair | Interproscan |
| GO:0003684 | Molecular Function | damaged DNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K09458 | fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II | EC:2.3.1.179 | Spliceosome | ko03041 | deepkoala |
| Lipid biosynthesis proteins | ko01004 | deepkoala |