Detailed information of g17992.t1 in Montipora capitata

Genomic Location: Sc0000841:83776...86346
NR annotation: XP_029184310.2, cholesterol 24-hydroxylase-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9WVK8Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46a1 PE=1 SV=1
Q9Y6A2Cholesterol 24-hydroxylase OS=Homo sapiens OX=9606 GN=CYP46A1 PE=1 SV=1
P30437Steroid 17-alpha-hydroxylase/17,20 lyase OS=Oncorhynchus mykiss OX=8022 GN=cyp17a1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000513 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00067
all species →		p450Cytochrome P450DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR017972
all species →		Conserved_siteCytochrome P450, conserved siteInterproscan
IPR001128
all species →		FamilyCytochrome P450Interproscan
IPR036396
all species →		Homologous_superfamilyCytochrome P450 superfamilyInterproscan
IPR039983
all species →		FamilyCholesterol 24-hydroxylaseInterproscan
IPR002401
all species →		FamilyCytochrome P450, E-class, group IInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR24293
all species →		CYTOCHROME P450 FAMILY 46 SUBFAMILY AInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005506
all species →		Molecular Functioniron ion bindingInterproscan
GO:0016705
all species →		Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenInterproscan
GO:0004497
all species →		Molecular Functionmonooxygenase activityInterproscan
GO:0020037
all species →		Molecular Functionheme bindingInterproscan
GO:0006707
all species →		Biological Processcholesterol catabolic processInterproscan
GO:0033781
all species →		Molecular Functioncholesterol 24-hydroxylase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for g17992.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g17992.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
219.9Max TPM
100.2Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 97.78 192.66
whole organisms · low pH treatment 15 15 105.64 219.86
whole organisms · extra low pH treatment pH treatment 12 12 97.45 175.51

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 192.66
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 174.69
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 163.83
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 163.20
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 150.31
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 148.77
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 140.05
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 128.30
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 106.59
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 88.41
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 84.72
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 69.14
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 65.93
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 62.26
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 58.86
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 55.50
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 47.11
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 43.51
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 41.56
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 34.07
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 33.85
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 219.86
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 190.15
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 162.78
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 144.09
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 134.46
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 133.45
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 110.40
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 76.86
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 76.64
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 74.33
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 72.56
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 64.88
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 42.97
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 41.57
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 39.65
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 175.51
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 168.13
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 130.29
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 128.59
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 118.18
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 108.34
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 86.91
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 75.45
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 56.11
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 42.41
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 41.77
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 37.72

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated19g14958.t10.961541921256497
Negatively correlated14g11255.t1-0.926723756646241

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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