Genomic Location: Sc0001087:13826...22739
NR annotation: XP_029204419.1, egl nine homolog 1-like isoform X5 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families
| CDS |
| g19864.t1 |
| Transcript |
| g19864.t1 |
| Protein |
| g19864.t1 |
| UniProt accession | Description |
|---|---|
| P59722 | Egl nine homolog 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Egln1 PE=2 SV=2 |
| Q9GZT9 | Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 |
| Q91YE3 | Egl nine homolog 1 OS=Mus musculus OX=10090 GN=Egln1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001316 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01753 all species → | zf-MYND | MYND finger | Domain | Interproscan |
| PF13640 all species → | 2OG-FeII_Oxy_3 | 2OG-Fe(II) oxygenase superfamily | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005123 all species → | Domain | Oxoglutarate/iron-dependent dioxygenase | Interproscan |
| IPR051559 all species → | Family | Hypoxia-inducible factor prolyl hydroxylases | Interproscan |
| IPR002893 all species → | Domain | Zinc finger, MYND-type | Interproscan |
| IPR044862 all species → | Domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Interproscan |
| IPR006620 all species → | Domain | Prolyl 4-hydroxylase, alpha subunit | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12907 all species → | EGL NINE HOMOLOG-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008198 all species → | Molecular Function | ferrous iron binding | Interproscan |
| GO:0031543 all species → | Molecular Function | peptidyl-proline dioxygenase activity | Interproscan |
| GO:0071456 all species → | Biological Process | cellular response to hypoxia | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0031418 all species → | Molecular Function | L-ascorbic acid binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09592 | EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase | EC:1.14.11.29 | Renal cell carcinoma | ko05211 | deepkoala |
Transcript abundance of g19864.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organisms · ambient pH treatment | 21 | 21 | 18.71 | 55.55 | |
| whole organisms · low pH treatment | 15 | 15 | 16.29 | 38.44 | |
| whole organisms · extra low pH treatment pH treatment | 12 | 12 | 16.60 | 45.25 |
Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.