Gene detail

Detailed information of g199.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_002170074.3, synapsin-2 [Hydra vulgaris]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q92777	Synapsin-2 OS=Homo sapiens OX=9606 GN=SYN2 PE=1 SV=4
Q6QM28	Synapsin OS=Helix pomatia OX=6536 GN=SYN PE=1 SV=1
Q64332	Synapsin-2 OS=Mus musculus OX=10090 GN=Syn2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000001 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000038 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000139 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000309 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000684 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0002427 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0002567 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0002667 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0005105 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0005216 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0007024 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0011567 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0012200 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02078 all species →	Synapsin	Synapsin, N-terminal domain	Domain	Interproscan
PF02750 all species →	Synapsin_C	Synapsin, ATP binding domain	Domain	Interproscan
PF14545 all species →	DBB	Dof, BCAP, and BANK (DBB) motif,	Domain	Interproscan
PF13202 all species →	EF-hand_5	EF hand	Domain	Interproscan
PF13499 all species →	EF-hand_7	EF-hand domain pair	Domain	Interproscan
PF02181 all species →	FH2	Formin Homology 2 Domain	Family	Interproscan
PF06371 all species →	Drf_GBD	Diaphanous GTPase-binding Domain	Repeat	Interproscan
PF06367 all species →	Drf_FH3	Diaphanous FH3 Domain	Repeat	Interproscan
PF00078 all species →	RVT_1	Reverse transcriptase (RNA-dependent DNA polymerase)	Domain	Interproscan
PF12781 all species →	AAA_9	ATP-binding dynein motor region	Domain	Interproscan
PF12780 all species →	AAA_8	P-loop containing dynein motor region D4	Domain	Interproscan
PF17857 all species →	AAA_lid_1	AAA+ lid domain	Domain	Interproscan
PF17852 all species →	Dynein_AAA_lid	Dynein heavy chain AAA lid domain	Domain	Interproscan
PF12777 all species →	MT	Microtubule-binding stalk of dynein motor	Domain	Interproscan
PF00071 all species →	Ras	Ras family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001359 all species →	Family	Synapsin	Interproscan
IPR020897 all species →	Domain	Synapsin, pre-ATP-grasp domain	Interproscan
IPR020898 all species →	Domain	Synapsin, ATP-binding domain	Interproscan
IPR013815 all species →	Homologous_superfamily	ATP-grasp fold, subdomain 1	Interproscan
IPR016185 all species →	Homologous_superfamily	Pre-ATP-grasp domain superfamily	Interproscan
IPR017893 all species →	Domain	DBB domain	Interproscan
IPR036770 all species →	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	Interproscan
IPR052446 all species →	Family	B-cell PI3K Activation and Signaling Adapters	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR052266 all species →	Family	Mitochondrial Rho GTPase/EF-hand domain-containing protein	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR010473 all species →	Domain	Formin, GTPase-binding domain	Interproscan
IPR042201 all species →	Homologous_superfamily	Formin, FH2 domain superfamily	Interproscan
IPR011989 all species →	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR014767 all species →	Domain	Diaphanous autoregulatory (DAD) domain	Interproscan
IPR015425 all species →	Domain	Formin, FH2 domain	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR051412 all species →	Family	Formin Homology Diaphanous subfamily	Interproscan
IPR010472 all species →	Domain	Formin, FH3 domain	Interproscan
IPR044933 all species →	Homologous_superfamily	Diaphanous, GTPase-binding domain superfamily	Interproscan
IPR014768 all species →	Domain	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain	Interproscan
IPR043128 all species →	Homologous_superfamily	Reverse transcriptase/Diguanylate cyclase domain	Interproscan
IPR001969 all species →	Active_site	Aspartic peptidase, active site	Interproscan
IPR053134 all species →	Family	RNA-directed DNA polymerase homolog	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR021109 all species →	Homologous_superfamily	Aspartic peptidase domain superfamily	Interproscan
IPR000477 all species →	Domain	Reverse transcriptase domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR006020 all species →	Domain	PTB/PI domain	Interproscan
IPR036259 all species →	Homologous_superfamily	MFS transporter superfamily	Interproscan
IPR050327 all species →	Family	Proton-linked Monocarboxylate Transporter	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR035706 all species →	Domain	Dynein heavy chain, ATP-binding dynein motor region	Interproscan
IPR024317 all species →	Domain	Dynein heavy chain, AAA module D4	Interproscan
IPR026983 all species →	Family	Dynein heavy chain	Interproscan
IPR041589 all species →	Domain	Dynein heavy chain 3, AAA+ lid domain	Interproscan
IPR041466 all species →	Domain	Dynein heavy chain, AAA 5 extension domain	Interproscan
IPR024743 all species →	Domain	Dynein heavy chain, coiled coil stalk	Interproscan
IPR011356 all species →	Family	Peptidase M17, leucine aminopeptidase/peptidase B	Interproscan
IPR001806 all species →	Family	Small GTPase	Interproscan
IPR020849 all species →	Family	Small GTPase, Ras-type	Interproscan
IPR005225 all species →	Domain	Small GTP-binding protein domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10841 all species →	SYNAPSIN	Interproscan
PTHR16267 all species →	BANK1/PIK3AP1 FAMILY MEMBER	Interproscan
PTHR46819 all species →	EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7	Interproscan
PTHR45691 all species →	PROTEIN DIAPHANOUS	Interproscan
PTHR24559 all species →	TRANSPOSON TY3-I GAG-POL POLYPROTEIN	Interproscan
PTHR47695 all species →	PID DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR11360 all species →	MONOCARBOXYLATE TRANSPORTER	Interproscan
PTHR46961 all species →	DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN	Interproscan
PTHR11963 all species →	LEUCINE AMINOPEPTIDASE-RELATED	Interproscan
PTHR24070 all species →	RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0007269 all species →	Biological Process	neurotransmitter secretion	Interproscan
GO:0030672 all species →	Cellular Component	synaptic vesicle membrane	Interproscan
GO:0008021 all species →	Cellular Component	synaptic vesicle	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0005102 all species →	Molecular Function	signaling receptor binding	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0060170 all species →	Cellular Component	ciliary membrane	Interproscan
GO:0098797 all species →	Cellular Component	plasma membrane protein complex	Interproscan
GO:1903569 all species →	Biological Process	positive regulation of protein localization to ciliary membrane	Interproscan
GO:0003779 all species →	Molecular Function	actin binding	Interproscan
GO:0030036 all species →	Biological Process	actin cytoskeleton organization	Interproscan
GO:0031267 all species →	Molecular Function	small GTPase binding	Interproscan
GO:0005884 all species →	Cellular Component	actin filament	Interproscan
GO:0030041 all species →	Biological Process	actin filament polymerization	Interproscan
GO:0016043 all species →	Biological Process	cellular component organization	Interproscan
GO:0004190 all species →	Molecular Function	aspartic-type endopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0008028 all species →	Molecular Function	monocarboxylic acid transmembrane transporter activity	Interproscan
GO:0016021 all species →	Cellular Component	membrane	Interproscan
GO:0007018 all species →	Biological Process	microtubule-based movement	Interproscan
GO:0030286 all species →	Cellular Component	dynein complex	Interproscan
GO:0045505 all species →	Molecular Function	dynein intermediate chain binding	Interproscan
GO:0051959 all species →	Molecular Function	dynein light intermediate chain binding	Interproscan
GO:0008233 all species →	Molecular Function	peptidase activity	Interproscan
GO:0019538 all species →	Biological Process	protein metabolic process	Interproscan
GO:0030145 all species →	Molecular Function	manganese ion binding	Interproscan
GO:0070006 all species →	Molecular Function	metalloaminopeptidase activity	Interproscan
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0019003 all species →	Molecular Function	GDP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07841	DIRAS2; DIRAS family, GTP-binding Ras-like 2	-	GTP-binding proteins	ko04031	deepkoala
K10413	DYNC1H; dynein cytoplasmic 1 heavy chain	-	Exosome	ko04147	deepkoala
K19941	SYN; synapsin	-	Membrane trafficking	ko04131	deepkoala
K23852	EFCAB7; EF-hand calcium-binding domain-containing protein 7	-	Cilium and associated proteins	ko03037	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →