Genomic Location: :...
NR annotation: XP_002164666.1, myo-inositol 2-dehydrogenase [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q9WYP5 | Myo-inositol 2-dehydrogenase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=iolG PE=1 SV=1 | ||||
| O05389 | Uncharacterized oxidoreductase YrbE OS=Bacillus subtilis (strain 168) OX=224308 GN=yrbE PE=3 SV=2 | ||||
| A0LVX1 | Inositol 2-dehydrogenase OS=Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B) OX=351607 GN=iolG PE=3 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | THAP |
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02894 | GFO_IDH_MocA_C | Oxidoreductase family, C-terminal alpha/beta domain | Domain | Interproscan |
| PF01408 | GFO_IDH_MocA | Oxidoreductase family, NAD-binding Rossmann fold | Family | Interproscan |
| PF00787 | PX | PX domain | Domain | Interproscan |
| PF00640 | PID | Phosphotyrosine interaction domain (PTB/PID) | Domain | Interproscan |
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF08238 | Sel1 | Sel1 repeat | Repeat | Interproscan |
| PF14223 | Retrotran_gag_2 | gag-polypeptide of LTR copia-type | Family | Interproscan |
| PF01512 | Complex1_51K | Respiratory-chain NADH dehydrogenase 51 Kd subunit | Family | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF17659 | DUF5521 | Family of unknown function (DUF5521) | Family | Interproscan |
| PF05485 | THAP | THAP domain | Domain | Interproscan |
| PF01756 | ACOX | Acyl-CoA oxidase | Family | Interproscan |
| PF00441 | Acyl-CoA_dh_1 | Acyl-CoA dehydrogenase, C-terminal domain | Domain | Interproscan |
| PF03564 | DUF1759 | Protein of unknown function (DUF1759) | Family | Interproscan |
| PF13650 | Asp_protease_2 | Aspartyl protease | Domain | Interproscan |
| PF01753 | zf-MYND | MYND finger | Domain | Interproscan |
| PF13640 | 2OG-FeII_Oxy_3 | 2OG-Fe(II) oxygenase superfamily | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004104 | Domain | Gfo/Idh/MocA-like oxidoreductase, C-terminal | Interproscan |
| IPR000683 | Domain | Gfo/Idh/MocA-like oxidoreductase, N-terminal | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR001683 | Domain | Phox homology | Interproscan |
| IPR036871 | Homologous_superfamily | PX domain superfamily | Interproscan |
| IPR027267 | Homologous_superfamily | AH/BAR domain superfamily | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR006020 | Domain | PTB/PI domain | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR047178 | Family | JNK-interacting protein 1 | Interproscan |
| IPR006597 | Repeat | Sel1-like repeat | Interproscan |
| IPR011990 | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR052323 | Family | LRP2-binding protein | Interproscan |
| IPR050837 | Family | Complex I 51 kDa subunit | Interproscan |
| IPR011538 | Domain | NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain | Interproscan |
| IPR001949 | Conserved_site | NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site | Interproscan |
| IPR037225 | Homologous_superfamily | NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily | Interproscan |
| IPR050285 | Family | STE20 Serine/Threonine-Protein Kinase | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR040893 | Family | RPA-related protein RADX | Interproscan |
| IPR012340 | Homologous_superfamily | Nucleic acid-binding, OB-fold | Interproscan |
| IPR006612 | Domain | THAP-type zinc finger | Interproscan |
| IPR038441 | Homologous_superfamily | THAP-type zinc finger superfamily | Interproscan |
| IPR052224 | Family | THAP domain-containing protein | Interproscan |
| IPR009100 | Homologous_superfamily | Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily | Interproscan |
| IPR036250 | Homologous_superfamily | Acyl-CoA dehydrogenase-like, C-terminal | Interproscan |
| IPR002655 | Domain | Acyl-CoA oxidase, C-terminal | Interproscan |
| IPR009075 | Domain | Acyl-CoA dehydrogenase/oxidase, C-terminal | Interproscan |
| IPR012258 | Family | Acyl-CoA oxidase | Interproscan |
| IPR046373 | Homologous_superfamily | Acyl-CoA oxidase/dehydrogenase, middle domain superfamily | Interproscan |
| IPR005312 | Family | Protein of unknown function DUF1759 | Interproscan |
| IPR001969 | Active_site | Aspartic peptidase, active site | Interproscan |
| IPR001878 | Domain | Zinc finger, CCHC-type | Interproscan |
| IPR021109 | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR001995 | Domain | Peptidase A2A, retrovirus, catalytic | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR006620 | Domain | Prolyl 4-hydroxylase, alpha subunit | Interproscan |
| IPR002893 | Domain | Zinc finger, MYND-type | Interproscan |
| IPR051559 | Family | Hypoxia-inducible factor prolyl hydroxylases | Interproscan |
| IPR005123 | Domain | Oxoglutarate/iron-dependent dioxygenase | Interproscan |
| IPR044862 | Domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42840 | NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED | Interproscan |
| PTHR45850 | SORTING NEXIN FAMILY MEMBER | Interproscan |
| PTHR47437 | JNK-INTERACTING PROTEIN 1-LIKE PROTEIN | Interproscan |
| PTHR44554 | LRP2-BINDING PROTEIN | Interproscan |
| PTHR11780 | NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 | Interproscan |
| PTHR48015 | SERINE/THREONINE-PROTEIN KINASE TAO | Interproscan |
| PTHR14944 | RPA-RELATED PROTEIN RADX | Interproscan |
| PTHR46927 | AGAP005574-PA | Interproscan |
| PTHR10909 | ELECTRON TRANSPORT OXIDOREDUCTASE | Interproscan |
| PTHR47331 | PHD-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR12907 | EGL NINE HOMOLOG-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0006740 | Biological Process | NADPH regeneration | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005078 | Molecular Function | MAP-kinase scaffold activity | Interproscan |
| GO:0007254 | Biological Process | JNK cascade | Interproscan |
| GO:0008432 | Molecular Function | JUN kinase binding | Interproscan |
| GO:0046328 | Biological Process | regulation of JNK cascade | Interproscan |
| GO:0005747 | Cellular Component | obsolete mitochondrial respiratory chain complex I | Interproscan |
| GO:0006120 | Biological Process | mitochondrial electron transport, NADH to ubiquinone | Interproscan |
| GO:0008137 | Molecular Function | NADH dehydrogenase (ubiquinone) activity | Interproscan |
| GO:0010181 | Molecular Function | FMN binding | Interproscan |
| GO:0051539 | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0023014 | Biological Process | signal transduction | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0043408 | Biological Process | regulation of MAPK cascade | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0003697 | Molecular Function | single-stranded DNA binding | Interproscan |
| GO:0005657 | Cellular Component | replication fork | Interproscan |
| GO:0006282 | Biological Process | regulation of DNA repair | Interproscan |
| GO:0016627 | Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors | Interproscan |
| GO:0003997 | Molecular Function | acyl-CoA oxidase activity | Interproscan |
| GO:0005777 | Cellular Component | peroxisome | Interproscan |
| GO:0006635 | Biological Process | fatty acid beta-oxidation | Interproscan |
| GO:0005504 | Molecular Function | fatty acid binding | Interproscan |
| GO:0006631 | Biological Process | fatty acid metabolic process | Interproscan |
| GO:0016402 | Molecular Function | pristanoyl-CoA oxidase activity | Interproscan |
| GO:0033540 | Biological Process | fatty acid beta-oxidation using acyl-CoA oxidase | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0055088 | Biological Process | lipid homeostasis | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| GO:0004190 | Molecular Function | aspartic-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0031418 | Molecular Function | L-ascorbic acid binding | Interproscan |
| GO:0008198 | Molecular Function | ferrous iron binding | Interproscan |
| GO:0031543 | Molecular Function | peptidyl-proline dioxygenase activity | Interproscan |
| GO:0071456 | Biological Process | cellular response to hypoxia | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00232 | E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase | EC:1.3.3.6 | Domain-containing proteins not elsewhere classified | ko04990 | deepkoala |
| Non-alcoholic fatty liver disease | ko04932 | deepkoala | |||
| DNA replication proteins | ko03032 | deepkoala | |||
| Alcoholic liver disease | ko04936 | deepkoala |