Detailed information of g2198.t1 in Montipora capitata

Genomic Location: Sc0000032:82779...89710
NR annotation: XP_027054825.1, apoptosis-inducing factor 1, mitochondrial-like [Pocillopora damicornis]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O95831Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1
Q9JM53Apoptosis-inducing factor 1, mitochondrial OS=Rattus norvegicus OX=10116 GN=Aifm1 PE=1 SV=1
Q9Z0X1Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005242 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF07992
all species →		Pyr_redox_2Pyridine nucleotide-disulphide oxidoreductaseDomainInterproscan
PF14721
all species →		AIF_CApoptosis-inducing factor, mitochondrion-associated, C-termDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR016156
all species →		Homologous_superfamilyFAD/NAD-linked reductase, dimerisation domain superfamilyInterproscan
IPR023753
all species →		DomainFAD/NAD(P)-binding domainInterproscan
IPR036188
all species →		Homologous_superfamilyFAD/NAD(P)-binding domain superfamilyInterproscan
IPR050446
all species →		FamilyFAD-dependent Oxidoreductases and Apoptosis RegulatorsInterproscan
IPR029324
all species →		DomainMitochondrial apoptosis-inducing factor, C-terminal domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43557
all species →		APOPTOSIS-INDUCING FACTOR 1Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0016491
all species →		Molecular Functionoxidoreductase activityInterproscan
GO:0050660
all species →		Molecular Functionflavin adenine dinucleotide bindingInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0005739
all species →		Cellular ComponentmitochondrionInterproscan
GO:0006915
all species →		Biological Processapoptotic processInterproscan
GO:0012501
all species →		Biological Processprogrammed cell deathInterproscan
GO:0016174
all species →		Molecular FunctionNAD(P)H oxidase H2O2-forming activityInterproscan
GO:0016651
all species →		Molecular Functionoxidoreductase activity, acting on NAD(P)HInterproscan
GO:0033108
all species →		Biological Processmitochondrial respiratory chain complex assemblyInterproscan
GO:0071949
all species →		Molecular FunctionFAD bindingInterproscan
GO:0046983
all species →		Molecular Functionprotein dimerization activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for g2198.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g2198.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
264.3Max TPM
144.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 155.22 264.30
whole organisms · low pH treatment 15 15 132.66 238.13
whole organisms · extra low pH treatment pH treatment 12 12 140.00 259.45

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 264.30
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 222.71
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 210.63
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 209.00
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 203.88
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 201.91
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 191.11
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 188.76
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 165.80
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 156.70
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 149.46
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 144.97
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 136.96
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 136.93
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 135.62
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 134.49
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 125.48
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 116.57
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 64.27
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 56.21
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 43.74
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 238.13
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 194.71
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 180.35
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 154.87
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 148.80
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 142.41
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 141.91
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 131.94
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 130.71
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 129.83
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 124.98
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 108.74
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 62.76
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 56.24
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 43.44
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 259.45
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 189.47
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 182.46
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 161.58
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 146.59
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 135.14
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 128.92
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 128.86
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 124.55
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 123.49
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 50.04
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 49.46

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated24g14202.t10.861304515393661
Negatively correlated27g8170.t1-0.830191854931633

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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