Genomic Location: :...
NR annotation: WP_259783334.1, aconitate hydratase AcnA [Aestuariispira ectoiniformans]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| P37032 | Aconitate hydratase A OS=Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) OX=272624 GN=acn PE=1 SV=1 |
| Q9I3F5 | Aconitate hydratase A OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=acnA PE=3 SV=1 |
| P25516 | Aconitate hydratase A OS=Escherichia coli (strain K12) OX=83333 GN=acnA PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00024 | PAN_1 | PAN domain | Domain | Interproscan |
| PF04275 | P-mevalo_kinase | Phosphomevalonate kinase | Family | Interproscan |
| PF03137 | OATP | Organic Anion Transporter Polypeptide (OATP) family | Family | Interproscan |
| PF20517 | TMEM127 | Transmembrane protein 127 | Family | Interproscan |
| PF05347 | Complex1_LYR | Complex 1 protein (LYR family) | Family | Interproscan |
| PF00330 | Aconitase | Aconitase family (aconitate hydratase) | Family | Interproscan |
| PF00694 | Aconitase_C | Aconitase C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002291 | Family | Phosphorylase kinase, gamma catalytic subunit | Interproscan |
| IPR003609 | Domain | PAN/Apple domain | Interproscan |
| IPR005919 | Family | Higher eukaryotic phosphomevalonate kinase | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR036259 | Homologous_superfamily | MFS transporter superfamily | Interproscan |
| IPR004156 | Family | Organic anion transporter polypeptide | Interproscan |
| IPR043128 | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR039041 | Family | Nav/unc-53 family | Interproscan |
| IPR046795 | Domain | Transmembrane protein 127, transmembrane region | Interproscan |
| IPR033331 | Family | Transmembrane protein 127 | Interproscan |
| IPR043159 | Homologous_superfamily | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily | Interproscan |
| IPR008011 | Domain | Complex 1 LYR protein domain | Interproscan |
| IPR045299 | Domain | NDUFA6, LYR domain | Interproscan |
| IPR016488 | Family | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 | Interproscan |
| IPR011990 | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR001119 | Domain | S-layer homology domain | Interproscan |
| IPR015931 | Homologous_superfamily | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 | Interproscan |
| IPR001030 | Domain | Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain | Interproscan |
| IPR000573 | Domain | Aconitase A/isopropylmalate dehydratase small subunit, swivel domain | Interproscan |
| IPR006249 | Family | Aconitase/Iron-responsive element-binding protein 2 | Interproscan |
| IPR036008 | Homologous_superfamily | Aconitase, iron-sulfur domain | Interproscan |
| IPR018136 | Binding_site | Aconitase family, 4Fe-4S cluster binding site | Interproscan |
| IPR044137 | Domain | Aconitase A, swivel domain | Interproscan |
| IPR015928 | Homologous_superfamily | Aconitase/3-isopropylmalate dehydratase, swivel | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13101 | PHOSPHOMEVALONATE KINASE | Interproscan |
| PTHR11388 | ORGANIC ANION TRANSPORTER | Interproscan |
| PTHR38681 | RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED | Interproscan |
| PTHR12784 | STEERIN | Interproscan |
| PTHR28358 | TRANSMEMBRANE PROTEIN 127 | Interproscan |
| PTHR12964 | NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT | Interproscan |
| PTHR33198 | ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED | Interproscan |
| PTHR11670 | ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004689 | Molecular Function | phosphorylase kinase activity | Interproscan |
| GO:0005516 | Molecular Function | calmodulin binding | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005964 | Cellular Component | phosphorylase kinase complex | Interproscan |
| GO:0005978 | Biological Process | glycogen biosynthetic process | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004631 | Molecular Function | phosphomevalonate kinase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0006695 | Biological Process | cholesterol biosynthetic process | Interproscan |
| GO:0019287 | Biological Process | isopentenyl diphosphate biosynthetic process, mevalonate pathway | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0007399 | Biological Process | nervous system development | Interproscan |
| GO:0022008 | Biological Process | neurogenesis | Interproscan |
| GO:0008285 | Biological Process | negative regulation of cell population proliferation | Interproscan |
| GO:0032006 | Biological Process | regulation of TOR signaling | Interproscan |
| GO:0032007 | Biological Process | negative regulation of TOR signaling | Interproscan |
| GO:0005747 | Cellular Component | obsolete mitochondrial respiratory chain complex I | Interproscan |
| GO:0006979 | Biological Process | response to oxidative stress | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003994 | Molecular Function | aconitate hydratase activity | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006099 | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0006101 | Biological Process | citrate metabolic process | Interproscan |
| GO:0030350 | Molecular Function | iron-responsive element binding | Interproscan |
| GO:0051539 | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K03950 | NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 | - | Peroxisome | ko04146 | deepkoala |
| Non-alcoholic fatty liver disease | ko04932 | deepkoala |