Gene detail

Detailed information of g26973.t1 in Montipora capitata

Genomic Location: xfSc0000000:638796...658100
NR annotation: XP_029197029.2, cytosolic 10-formyltetrahydrofolate dehydrogenase-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g26973.t1

atgctcagtgcttttcgttttgtacagtttgccgcagtgaaaacaacgaggaacatctacacaaccagaaacgttatgggttccttgaaggtcgcggtgatcggacagtcacagtttggcttggaagtttacaaaagtctgcgctcaaaaggtcatgaaattgtcggagtctttaccgtccccgatgtgaaaggaaagccagacattttagctactggagcagaacaagacggtgttaaagtttttaagttttctcgatggaggacaaaaggagaacccattcgagaggttgtcgatacgtacaaggcttgcggtgctgaactcaatgttttgccattttgctcacaatttattcctatgaatgtgatcgactttccaaaacatggctcaataatttatcatccttccctactgccaagacacagaggggcatccgccataaattggactcttatggaaggtgataagcaaggaggtttcagtgtattttgggctgatgatggtctagatactggtcctattctgcttcaaaagagtgtcgacattgatctaaatgatacagttgacacattgtataacagattcctgtttccagaaggcatcaaaggcatggttgaagcggttgatttaattagtgacggaaaggcaccaaaaatccctcaaccagaagaaggggcaacttatgataaaatctggaaaaagaaagaggttgcaaagataaattttgaccagtcagcagagatgctacacaattttattcgtggaaatgacaagcttccaggagcttggggcgtgatagatggccatcaagttactctgtatggctcctcactgacttctggtgatacacctcctgacgggacccctgtgacaatagaaggctcagaggtgcctgctattgtgcacaagggtggtatgacactgactggagtagatggaaagatgttaactgtaaagactttgcaacttgaagatgggcgcatgatccaagcagctaagtttggtcagatggaggaagcagctgaggcgattgagcttacagaggaggagaaaagcatggaggcaaaactgagggaaatatgggctgggattttggcaaaccccgatattcttgaagatacagactttttcaaagctggtgctggatccatggatgttacaaggctcattgaagaactgaaagaagctttctcaatagtgttagaagcagaagacatttacatgaatacaagatatggggattttgttcgcctctctgtcctgagatctcgaggtggaggactggaggaattcagttgtaaaactgttgacatggatgtgaacaacatgacagtttgcatgcccaatcagttgttcattaatggtgaatttgtggactcatccagtggaagaacatttgattgcatcaacccagctgatggttcggttatcacccaagtggctttagcatcaattgaggatgtggatgctgctgtcacagctgcaaaggaagccttttaccatgggccttggggaacaatgaatgccagagaccgtgggcacctaatgtacaaacttgctgaacttatggatgaacacagagaagaacttgcaacaatagagtcacttgattcaggggctgtgtacacacttgccctcaagactcacgttggcatgtcaattgacacagtgcgttactttgcaggatgggcagacaaaattcaaggattaaccattccaatcaacaatgctaaaccaaacaggaatctctccttcacaaagcgagtgcctattggtgtctgtggtttgattgtgccttggaactatcctctgatgatgttagcttggaagatatctcctctgttggcagctggcaacacagtgatcctcaaaccagcccaggtgaccccacttacagcactcaagtttgctgagctttcagctaaagcaggatttccaaaaggtgtcatcaacattttaccaggatcaggttctgttgtaggcaataggatttgttctcatcctgacattaggaaagttggttttactggatcaactgaaactggcaaatcaatcatggaaagttgtgctgtcagcaacttaaagaagtgttctctggagcttggtggcaaatcccctttgattatttttcacgactgtgatatggacagggctgtcagacagggaatgatggcttgcatgtttaacaaaggagagaactgcatagcagctgggcgtctgtttgttgaggcatctattcacgatgaatatgtgacaagagtggtcgaggagatcaagaaaatgaaaatcggagatccgcttgaccgctcaacagatcacgggcctcaaaatcacaaagcccaccttgattcccttcttgagtatgttaacaaaggagttgctgaaggtgccaagttagtttatggtggcaagcaagtggacaggccaggattcttctttgagcctactgtatttactgacgtgcaggatggaacatttttggccacggaggaatcctttggtcccatcatgatcatttccaaatttgaaaatggagacattgagggtgttttgaagagtgccaatggtaccgagtacggtcttgcctccggtgtttttacgaaggatttaagcaaggctctctgtgtagctgatggtttagatgcgggaacttgctttgtcaacacttacaacaagactgatgtggctgctccctttggaggcttcaagcagtctggctttggtaaagatttgggggaagaagctctcaatgaatacttgaagactaaagtgactacagttgaatactaa

Transcript

g26973.t1

ATGCTCAGTGCTTTTCGTTTTGTACAGTTTGCCGCAGTGAAAACAACGAGGAACATCTACACAACCAGAAACGTTATGGGTTCCTTGAAGGTCGCGGTGATCGGACAGTCACAGTTTGGCTTGGAAGTTTACAAAAGTCTGCGCTCAAAAGGTCATGAAATTGTCGGAGTCTTTACCGTCCCCGATGTGAAAGGAAAGCCAGACATTTTAGCTACTGGAGCAGAACAAGACGGTGTTAAAGTTTTTAAGTTTTCTCGATGGAGGACAAAAGGAGAACCCATTCGAGAGGTTGTCGATACGTACAAGGCTTGCGGTGCTGAACTCAATGTTTTGCCATTTTGCTCACAATTTATTCCTATGAATGTGATCGACTTTCCAAAACATGGCTCAATAATTTATCATCCTTCCCTACTGCCAAGACACAGAGGGGCATCCGCCATAAATTGGACTCTTATGGAAGGTGATAAGCAAGGAGGTTTCAGTGTATTTTGGGCTGATGATGGTCTAGATACTGGTCCTATTCTGCTTCAAAAGAGTGTCGACATTGATCTAAATGATACAGTTGACACATTGTATAACAGATTCCTGTTTCCAGAAGGCATCAAAGGCATGGTTGAAGCGGTTGATTTAATTAGTGACGGAAAGGCACCAAAAATCCCTCAACCAGAAGAAGGGGCAACTTATGATAAAatctggaaaaagaaagaggTTGCAAAGATAAATTTTGACCAGTCAGCAGAGATGCTACACAATTTTATTCGTGGAAATGACAAGCTTCCAGGAGCTTGGGGCGTGATAGATGGCCATCAAGTTACTCTGTATGGCTCCTCACTGACTTCTGGTGATACACCTCCTGACGGGACCCCTGTGACAATAGAAGGCTCAGAGGTGCCTGCTATTGTGCACAAGGGTGGTATGACACTGACTGGAGTAGATGGAAAGATGTTAACTGTAAAGACTTTGCAACTTGAAGATGGGCGCATGATCCAAGCAGCTAAGTTTGGTCAGATGGAGGAAGCAGCTGAGGCGATTGAGCTTACAGAGGAGGAGAAAAGCATGGAGGCAAAACTGAGGGAAATATGGGCTGGGATTTTGGCAAACCCCGATATTCTTGAAGATACAGACTTTTTCAAAGCTGGTGCTGGATCCATGGATGTTACAAGGCTCATTGAAGAACTGAAAGAAGCTTTCTCAATAGTGTTAGAAGCAGAAGACATTTACATGAATACAAGATATGGGGATTTTGTTCGCCTCTCTGTCCTGAGATCTCGAGGTGGAGGACTGGAGGAATTCAGTTGTAAAACTGTTGACATGGATGTGAACAACATGACAGTTTGCATGCCCAATCAGTTGTTCATTAATGGTGAATTTGTGGACTCATCCAGTGGAAGAACATTTGATTGCATCAACCCAGCTGATGGTTCGGTTATCACCCAAGTGGCTTTAGCATCAATTGAGGATGTGGATGCTGCTGTCACAGCTGCAAAGGAAGCCTTTTACCATGGGCCTTGGGGAACAATGAATGCCAGAGACCGTGGGCACCTAATGTACAAACTTGCTGAACTTATGGATGAACACAGAGAAGAACTTGCAACAATAGAGTCACTTGATTCAGGGGCTGTGTACACACTTGCCCTCAAGACTCACGTTGGCATGTCAATTGACACAGTGCGTTACTTTGCAGGATGGGCAGACAAAATTCAAGGATTAACCATTCCAATCAACAATGCTAAACCAAACAGGAATCTCTCCTTCACAAAGCGAGTGCCTATTGGTGTCTGTGGTTTGATTGTGCCTTGGAACTATCCTCTGATGATGTTAGCTTGGAAGATATCTCCTCTGTTGGCAGCTGGCAACACAGTGATCCTCAAACCAGCCCAGGTGACCCCACTTACAGCACTCAAGTTTGCTGAGCTTTCAGCTAAAGCAGGATTTCCAAAAGGTGTCATCAACATTTTACCAGGATCAGGTTCTGTTGTAGGCAATAGGATTTGTTCTCATCCTGACATTAGGAAAGTTGGTTTTACTGGATCAACTGAAACTGGCAAATCAATCATGGAAAGTTGTGCTGTCAGCAACTTAAAGAAGTGTTCTCTGGAGCTTGGTGGCAAATCCCCTTTGATTATTTTTCACGACTGTGATATGGACAGGGCTGTCAGACAGGGAATGATGGCTTGCATGTTTAACAAAGGAGAGAACTGCATAGCAGCTGGGCGTCTGTTTGTTGAGGCATCTATTCACGATGAATATGTGACAAGAGTGGTCGAGGagatcaagaaaatgaaaatcggAGATCCGCTTGACCGCTCAACAGATCACGGGCCTCAAAATCACAAAGCCCACCTTGATTCCCTTCTTGAGTATGTTAACAAAGGAGTTGCTGAAGGTGCCAAGTTAGTTTATGGTGGCAAGCAAGTGGACAGGCCAGGATTCTTCTTTGAGCCTACTGTATTTACTGACGTGCAGGATGGAACATTTTTGGCCACGGAGGAATCCTTTGGTCCCATCATGATCATTTCCAAATTTGAAAATGGAGACATTGAGGGTGTTTTGAAGAGTGCCAATGGTACCGAGTACGGTCTTGCCTCCGGTGTTTTTACGAAGGATTTAAGCAagGCTCTCTGTGTAGCTGATGGTTTAGATGCGGGAACTTGCTTTGTCAACACTTACAACAAGACTGATGTGGCTGCTCCCTTTGGAGGCTTCAAGCAGTCTGGCTTTGGTAAAGATTTGGGGGAAGAAGCTCTCAATGAATACTTGAAGACTAAAGTGACTACAGTTGAATACTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6GNL7	Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Xenopus laevis OX=8355 GN=aldh1l1 PE=2 SV=1
Q63ZT8	Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Xenopus tropicalis OX=8364 GN=aldh1l1 PE=2 SV=1
Q3SY69	Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004225 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02911 all species →	Formyl_trans_C	Formyl transferase, C-terminal domain	Domain	Interproscan
PF00551 all species →	Formyl_trans_N	Formyl transferase	Domain	Interproscan
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan
PF00550 all species →	PP-binding	Phosphopantetheine attachment site	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR037022 all species →	Homologous_superfamily	Formyl transferase, C-terminal domain superfamily	Interproscan
IPR005793 all species →	Domain	Formyl transferase, C-terminal	Interproscan
IPR002376 all species →	Domain	Formyl transferase, N-terminal	Interproscan
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan
IPR036736 all species →	Homologous_superfamily	ACP-like superfamily	Interproscan
IPR001555 all species →	Active_site	Phosphoribosylglycinamide formyltransferase, active site	Interproscan
IPR036477 all species →	Homologous_superfamily	Formyl transferase, N-terminal domain superfamily	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR011407 all species →	Family	10-formyltetrahydrofolate dehydrogenase	Interproscan
IPR009081 all species →	Domain	Phosphopantetheine binding ACP domain	Interproscan
IPR029510 all species →	Conserved_site	Aldehyde dehydrogenase, glutamic acid active site	Interproscan
IPR011034 all species →	Homologous_superfamily	Formyl transferase-like, C-terminal domain superfamily	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11699 all species →	ALDEHYDE DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0009058 all species →	Biological Process	biosynthetic process	Interproscan
GO:0004029 all species →	Molecular Function	aldehyde dehydrogenase (NAD+) activity	Interproscan
GO:0016155 all species →	Molecular Function	formyltetrahydrofolate dehydrogenase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006730 all species →	Biological Process	one-carbon metabolic process	Interproscan
GO:0009258 all species →	Biological Process	10-formyltetrahydrofolate catabolic process	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00289	ALDH1L; formyltetrahydrofolate dehydrogenase	EC:1.5.1.6	One carbon pool by folate	ko00670	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g26973.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

48TPM > 0

3Conditions

241.4Max TPM

89.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	21	87.89	220.68
whole organisms · low pH treatment	15	15	85.21	235.47
whole organisms · extra low pH treatment pH treatment	12	12	95.83	241.41

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	220.68
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	187.05
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	179.53
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	177.61
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	159.13
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	134.34
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	101.82
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	78.38
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	77.61
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	61.76
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	61.33
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	60.81
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	51.69
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	51.45
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	47.62
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	43.72
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	41.39
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	30.07
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	28.73
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	25.56
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	25.49
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	235.47
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	206.42
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	205.22
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	80.43
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	72.53
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	63.05
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	61.55
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	61.44
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	59.94
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	52.95
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	50.42
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	38.89
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	35.40
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	28.12
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	26.36
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	241.41
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	237.30
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	227.01
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	74.83
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	65.13
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	64.39
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	56.11
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	53.42
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	46.71
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	29.28
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	28.43
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	25.93

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.