Detailed information of g27052.t1 in Montipora capitata

Genomic Location: xfSc0000003:24561...65543
NR annotation: XP_044176473.1, THO complex subunit 2-like isoform X1 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
B1AZI6THO complex subunit 2 OS=Mus musculus OX=10090 GN=Thoc2 PE=1 SV=1
C1FXW9THO complex subunit 2 OS=Dasypus novemcinctus OX=9361 GN=THOC2 PE=3 SV=1
B0KWH8THO complex subunit 2 OS=Callithrix jacchus OX=9483 GN=THOC2 PE=3 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003728 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF11732
all species →		Thoc2Transcription- and export-related complex subunitFamilyInterproscan
PF11262
all species →		Tho2Transcription factor/nuclear export subunit protein 2FamilyInterproscan
PF16134
all species →		THOC2_NTHO complex subunit 2 N-terminusFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR021726
all species →		DomainTHO complex, subunitTHOC2, N-terminalInterproscan
IPR040007
all species →		FamilyTHO complex subunit 2Interproscan
IPR021418
all species →		DomainTHO complex, subunitTHOC2, C-terminalInterproscan
IPR032302
all species →		DomainTHO complex subunit 2, N-terminal domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR21597
all species →		THO2 PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000347
all species →		Cellular ComponentTHO complexInterproscan
GO:0000445
all species →		Cellular ComponentTHO complex part of transcription export complexInterproscan
GO:0003729
all species →		Molecular FunctionmRNA bindingInterproscan
GO:0006397
all species →		Biological ProcessmRNA processingInterproscan
GO:0006406
all species →		Biological ProcessmRNA export from nucleusInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12879THOC2; THO complex subunit 2-Spliceosomeko03041deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g27052.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
328.0Max TPM
155.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 158.75 328.00
whole organisms · low pH treatment 15 15 150.89 309.58
whole organisms · extra low pH treatment pH treatment 12 12 153.80 293.69

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 328.00
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 295.93
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 282.93
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 265.31
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 261.05
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 151.32
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 143.90
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 138.73
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 138.14
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 138.08
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 137.34
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 130.08
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 125.85
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 125.05
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 118.78
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 114.70
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 99.44
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 98.18
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 88.62
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 85.92
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 66.41
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 309.58
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 304.81
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 271.98
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 144.64
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 143.18
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 141.29
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 130.06
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 126.74
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 119.50
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 118.66
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 111.28
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 108.19
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 80.10
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 77.25
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 76.13
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 293.69
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 279.55
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 232.09
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 144.10
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 131.08
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 129.70
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 128.14
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 127.05
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 124.49
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 89.15
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 86.89
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 79.69

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated25g27297.t10.963903179694366
Negatively correlated11g12815.t1-0.908188489950077

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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