Gene detail

Detailed information of g2995.t1 in Acropora digitifera

Genomic Location: chr2Alt:7386191...7399483
NR annotation: XP_029192647.2, A disintegrin and metalloproteinase with thrombospondin motifs 6-like isoform X1 [Acropora millepora]
Species Acropora digitifera · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g2995.t1

ATGTCTAAAATTGTCACACCGCAAATGAAGCATTCAAATGCGTTGTTGCCTTATGCAATTTTAAGTCTCTTAATTTTGGTCATCGGGCTCTCAAGTGCCAAGCCATACCAGGAAATCCATCACTTGTTAACCGAGGAAGAAAGAGAGGGGATCTTCGGACACACTTCTGCAGAATATGTTCAAGAGTATGCCATAACCCATCCTGTTCAAGTCGACATAAATGGAAGATTCTTGTCGCGAGACCTTGCTAATGGCAATAGCCGCCGCAAGAGAGATATCGGTAGCCCTTCCAAAGAGTCTGTTTTCTTCAAAATGTCTGCTTTCGGTCAAGATTACCAGTTGAACGTTACGCTGAACGATGTGCTATTCTCGCCTCATTTTGAAATGGAGGTTCGTGGAAATGGCAGCTCCGAATTTCATTATGACATTGAGCACTGCCATTATATAGGCCAGCTCCTTCCAAAAGATGGAGAGACGAGCAAGGTGGCTGTCAGTAACTGCGATGGACTGAAAGGCATGATTCGCACTCTAAAAGATCTTTTCTTGGTTCACCCATTGCCTGCCCGTTTGGGACTGGAAAAGAACAAAACCCGAGCTCATGTGATCCAAAGGAGATCCTTGACGCCATTGCAGGCTCTTGGGATGGCTATGACCGAAGAAGAAAGATCTGAGAAATGGTGTGGAGTGAAAGGAACATCAAAATTTCAACAATCCGATAATTCCAGCAAAACTTCACACGCTATCTTCCGTCGGTCAGCAGACGTGGATTTTGCTCGCGTGAGAACCATTGAGTCGATGGTTGTTGTTGAGAAAGTGATGACAAAGTTTTATGGAGTTGAGGCGATCAGGACCTATGTACCAACGCTGGTCAACATTGCCCACGGTCTTCTAGCTGATGCATCTATTGGAGCTAATATCAAGTACGTTATCCAGAAACTACTGATTCTGGAAGATGACGTGGATGGTCTTGTGCTGGAGAATCATGCAGCCAGTACTTTGTCAAACTTCTGTAACTGGACGATAGGACGAAATACCGAAGACGATAGCGACCCGGCTCACTTTGATCATGCGGCTCTGTTTGCCAAGTACGATTTTTGTAGAGACAAAAAGGGAAACAAAAAAGAACATGAAAGGGCCAAAAAAGAAGAAACAGAAGGATGTGGAACTATACTGGGCTTGGCTGACTTAAAGGGCATGTGTAAACGAGGCAGCAGTTGTACTTTGAGTAAAGACACAGGGCTGGGGACAGCATTCACCTTGGCTCACGAAACAGGGCATAATTTAGGAGCTGAGCACGACTCTGAGGGAAACAAATGTAGTAATGGAGTCAACATCATGGCAACCAAAGCCAGCGGGAAATTAACAGCATTTGATTGGTCATCGTGCAGCAGGAATTACATCACTAACTTTCTGGATACTGCCCAAGCGGAATGTCTTAACGATCCAGCCAACCACACCGTATCGATACCGTCAGAGAAACCGGGAATCATTTATGATGGGACCACGCAATGTGTGCGCATGTTTGGCAAAGGATCGCGTGTTTGTGATATCCCGGATTTAATGCTGAATATGTGTATGAACTTGTTCTGTGAGAAACCAGATGGATATTGTTCCTCAAACGATGAACCAGCTGCAGACGGGACAGAGTGTCTCGCTAACAAGTGGTGTAGTTATGGCAAGTGTGTTACCAAGGGAACTAAAGGGGACCCAGACGTTGACGGCACCTGGGGAGCCTGGGGAGAATGGAGTGCGTGTTATCCTTCCTGTGGGGGAGGGCTGACTAAGCGAGTCCGTGAGTGCAATAACCCCGCACCGCAGCGCGGAGGAAGTTTGTGCGGCGGCCGGGGCACAGAGTATAGATACTGCAATAAGAAATGCCCACCAAATTCTGAACATCCAAGAATGGAGCAATGTCGTAACAAGAGAAACGTACAATTTGAAGGACCGATAAAAACGTTTAACTGGATTTATGACCCGTCCTTTGTTTCAGGTTCTCCCAAGTGTGTTTTGAGTTGTGCCACAACTGAAGGAGACACCACGTCGTTTGGAAGCGTCAAGGACGGCACTCCATGCTCTGACACGCCCAACAGTGGTGTTTGCCTAAGTGGACAATGCAAGCTGATTGGATGCGATGGCGCTGTAGATTCGCGAGCGAAGTTAGACAGATGTGGAGTGTGCAATGGTGACGGGTCCAGTTGCTCTGTAGGCAGTAACCAAGGCAACAAGCCGAAGCCCCAATCCACACTAGGACCAGTGCCCACACAGTCGACCGAATCTCCTAGTACCCGGCCCACACAGTCGACCGAATCTCCTAGTACCCGGCCCACACAGTCGACCCAATCTCCTAGTACCCGGCCCACACAGTCGACCCAATCTCCTAGTACCCGGCCTCCAGTGCTTGGCGAAAACCTCATGACATTCTTATATCACCGTGTACCCGATGACTTTTACCCCACCATTGCAATTCTTCCGTCTGGAGCTCGAAATATCACAATCACAGAAATTACAGAATCAAGTAACAACTTAATGCTGAAAGACGATTATTGGTTTGACATCATCGATTACAGTCAGTTTTCACCTGACAACCTACGACAAGACTTCGCCGGCGCTGGAACTACATTTTGGGTCACAAAACTCTATGAGAAAGAAACTATCACTTCATCAGGTCCTCTGAATATGAATTTAACTCTTCTGATCGAAGTAAATGAACCAGGGCAGGAATACAAAGTCGAATACCGATACATCCTAACCAGTGTTGAAGAGGAGGTTTCCTCTGGGGAGAACCACTTCCCAGATCGTTTCCGTCTTAGCAATGAAGCTAGCAAATATGTCAGCGACGTCAGTCAATTCGACAAAAAGCCTGAAACGAAATGGATCATGTATTCAGCTACGTGCTCTGCTTCATGCGGTGGAGGAATTGAGATCGTCACTGCTGTATGTGTTCGTGTGGACGATGAATCTCCAGTTGGAGATCAATTCTGCGAGGAAAAGAGGCCCGGGAACCAGTACAAAAAGTGTAACACGCAATTATGTCCGGCAAGGTAA

Transcript

chr2Alt.g2995.t1

TCCCGAGGAAGCTATCAAGAACAATATAGTGGTGACAGAAGCAATAGCTTGGAAATTGGAAATTGAACTGGAAAGCAGCCAGTTTAAGTGAAAAGTAATACTTAAAACTATCTGAAATTACACTGCCGTCTGTAACTTGTGAGAAAATCGAATTTTAACAGTGGGGATCCAATAGATGATCTACTGTCATCGTAAAGCCATCGGTTTTTGCACGAAAACCCCATTTTCTGGTCGTCCCCGTGCAGTAAGGTGATGTCTAAAATTGTCACACCGCAAATGAAGCATTCAAATGCGTTGTTGCCTTATGCAATTTTAAGTCTCTTAATTTTGGTCATCGGGCTCTCAAGTGCCAAGCCATACCAGGAAATCCATCACTTGTTAACCGAGGAAGAAAGAGAGGGGATCTTCGGACACACTTCTGCAGAATATGTTCAAGAGTATGCCATAACCCATCCTGTTCAAGTCGACATAAATGGAAGATTCTTGTCGCGAGACCTTGCTAATGGCAATAGCCGCCGCAAGAGAGATATCGGTAGCCCTTCCAAAGAGTCTGTTTTCTTCAAAATGTCTGCTTTCGGTCAAGATTACCAGTTGAACGTTACGCTGAACGATGTGCTATTCTCGCCTCATTTTGAAATGGAGGTTCGTGGAAATGGCAGCTCCGAATTTCATTATGACATTGAGCACTGCCATTATATAGGCCAGCTCCTTCCAAAAGATGGAGAGACGAGCAAGGTGGCTGTCAGTAACTGCGATGGACTGAAAGGCATGATTCGCACTCTAAAAGATCTTTTCTTGGTTCACCCATTGCCTGCCCGTTTGGGACTGGAAAAGAACAAAACCCGAGCTCATGTGATCCAAAGGAGATCCTTGACGCCATTGCAGGCTCTTGGGATGGCTATGACCGAAGAAGAAAGATCTGAGAAATGGTGTGGAGTGAAAGGAACATCAAAATTTCAACAATCCGATAATTCCAGCAAAACTTCACACGCTATCTTCCGTCGGTCAGCAGACGTGGATTTTGCTCGCGTGAGAACCATTGAGTCGATGGTTGTTGTTGAGAAAGTGATGACAAAGTTTTATGGAGTTGAGGCGATCAGGACCTATGTACCAACGCTGGTCAACATTGCCCACGGTCTTCTAGCTGATGCATCTATTGGAGCTAATATCAAGTACGTTATCCAGAAACTACTGATTCTGGAAGATGACGTGGATGGTCTTGTGCTGGAGAATCATGCAGCCAGTACTTTGTCAAACTTCTGTAACTGGACGATAGGACGAAATACCGAAGACGATAGCGACCCGGCTCACTTTGATCATGCGGCTCTGTTTGCCAAGTACGATTTTTGTAGAGACAAAAAGGGAAACAAAAAAGAACATGAAAGGGCCAAAAAAGAAGAAACAGAAGGATGTGGAACTATACTGGGCTTGGCTGACTTAAAGGGCATGTGTAAACGAGGCAGCAGTTGTACTTTGAGTAAAGACACAGGGCTGGGGACAGCATTCACCTTGGCTCACGAAACAGGGCATAATTTAGGAGCTGAGCACGACTCTGAGGGAAACAAATGTAGTAATGGAGTCAACATCATGGCAACCAAAGCCAGCGGGAAATTAACAGCATTTGATTGGTCATCGTGCAGCAGGAATTACATCACTAACTTTCTGGATACTGCCCAAGCGGAATGTCTTAACGATCCAGCCAACCACACCGTATCGATACCGTCAGAGAAACCGGGAATCATTTATGATGGGACCACGCAATGTGTGCGCATGTTTGGCAAAGGATCGCGTGTTTGTGATATCCCGGATTTAATGCTGAATATGTGTATGAACTTGTTCTGTGAGAAACCAGATGGATATTGTTCCTCAAACGATGAACCAGCTGCAGACGGGACAGAGTGTCTCGCTAACAAGTGGTGTAGTTATGGCAAGTGTGTTACCAAGGGAACTAAAGGGGACCCAGACGTTGACGGCACCTGGGGAGCCTGGGGAGAATGGAGTGCGTGTTATCCTTCCTGTGGGGGAGGGCTGACTAAGCGAGTCCGTGAGTGCAATAACCCCGCACCGCAGCGCGGAGGAAGTTTGTGCGGCGGCCGGGGCACAGAGTATAGATACTGCAATAAGAAATGCCCACCAAATTCTGAACATCCAAGAATGGAGCAATGTCGTAACAAGAGAAACGTACAATTTGAAGGACCGATAAAAACGTTTAACTGGATTTATGACCCGTCCTTTGTTTCAGGTTCTCCCAAGTGTGTTTTGAGTTGTGCCACAACTGAAGGAGACACCACGTCGTTTGGAAGCGTCAAGGACGGCACTCCATGCTCTGACACGCCCAACAGTGGTGTTTGCCTAAGTGGACAATGCAAGCTGATTGGATGCGATGGCGCTGTAGATTCGCGAGCGAAGTTAGACAGATGTGGAGTGTGCAATGGTGACGGGTCCAGTTGCTCTGTAGGCAGTAACCAAGGCAACAAGCCGAAGCCCCAATCCACACTAGGACCAGTGCCCACACAGTCGACCGAATCTCCTAGTACCCGGCCCACACAGTCGACCGAATCTCCTAGTACCCGGCCCACACAGTCGACCCAATCTCCTAGTACCCGGCCCACACAGTCGACCCAATCTCCTAGTACCCGGCCTCCAGTGCTTGGCGAAAACCTCATGACATTCTTATATCACCGTGTACCCGATGACTTTTACCCCACCATTGCAATTCTTCCGTCTGGAGCTCGAAATATCACAATCACAGAAATTACAGAATCAAGTAACAACTTAATGCTGAAAGACGATTATTGGTTTGACATCATCGATTACAGTCAGTTTTCACCTGACAACCTACGACAAGACTTCGCCGGCGCTGGAACTACATTTTGGGTCACAAAACTCTATGAGAAAGAAACTATCACTTCATCAGGTCCTCTGAATATGAATTTAACTCTTCTGATCGAAGTAAATGAACCAGGGCAGGAATACAAAGTCGAATACCGATACATCCTAACCAGTGTTGAAGAGGAGGTTTCCTCTGGGGAGAACCACTTCCCAGATCGTTTCCGTCTTAGCAATGAAGCTAGCAAATATGTCAGCGACGTCAGTCAATTCGACAAAAAGCCTGAAACGAAATGGATCATGTATTCAGCTACGTGCTCTGCTTCATGCGGTGGAGGAATTGAGATCGTCACTGCTGTATGTGTTCGTGTGGACGATGAATCTCCAGTTGGAGATCAATTCTGCGAGGAAAAGAGGCCCGGGAACCAGTACAAAAAGTGTAACACGCAATTATGTCCGGCAAGGTAATTTGCTGACCAAGAAGAATGTGAATCGTTTCATATACAAAGAAAAAATAGTATTTTCCATTTCTTGATTAGTATTTTCTCTTACTTAGAGTCTGTCTATATTGCTTCTAGCCTTCTGTTGGAACCAATTAATGACAGTATGATAAAACCACGATTTTAATTTGCCAATCAAATGAAAGTGGGAAAAATAAACATCATCAAAACAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9UKP5	A disintegrin and metalloproteinase with thrombospondin motifs 6 OS=Homo sapiens OX=9606 GN=ADAMTS6 PE=1 SV=2
Q8TE60	A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Homo sapiens OX=9606 GN=ADAMTS18 PE=1 SV=3
Q4VC17	A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Mus musculus OX=10090 GN=Adamts18 PE=2 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF19236 all species →	ADAMTS_CR_3	ADAMTS cysteine-rich domain	Domain	Interproscan
PF01562 all species →	Pep_M12B_propep	Reprolysin family propeptide	Family	Interproscan
PF00090 all species →	TSP_1	Thrombospondin type 1 domain	Domain	Interproscan
PF19030 all species →	TSP1_ADAMTS	Thrombospondin type 1 domain	Domain	Interproscan
PF01421 all species →	Reprolysin	Reprolysin (M12B) family zinc metalloprotease	Domain	Interproscan
PF17771 all species →	ADAMTS_CR_2	ADAMTS cysteine-rich domain 2	Domain	Interproscan
PF05986 all species →	ADAMTS_spacer1	ADAM-TS Spacer 1	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050439 all species →	Family	ADAMTS and ADAMTS-like	Interproscan
IPR000884 all species →	Repeat	Thrombospondin type-1 (TSP1) repeat	Interproscan
IPR045371 all species →	Domain	ADAMTS/ADAMTS-like, cysteine-rich domain 3	Interproscan
IPR036383 all species →	Homologous_superfamily	Thrombospondin type-1 (TSP1) repeat superfamily	Interproscan
IPR001590 all species →	Domain	Peptidase M12B, ADAM/reprolysin	Interproscan
IPR002870 all species →	Domain	Peptidase M12B, propeptide	Interproscan
IPR024079 all species →	Homologous_superfamily	Metallopeptidase, catalytic domain superfamily	Interproscan
IPR013273 all species →	Family	ADAMTS/ADAMTS-like	Interproscan
IPR041645 all species →	Domain	ADAMTS, cysteine-rich domain 2	Interproscan
IPR010294 all species →	Domain	ADAMTS/ADAMTS-like, Spacer 1	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13723 all species →	ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004222 all species →	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0030198 all species →	Biological Process	extracellular matrix organization	Interproscan
GO:0031012 all species →	Cellular Component	extracellular matrix	Interproscan
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08621	ADAMTS6; a disintegrin and metalloproteinase with thrombospondin motifs 6	EC:3.4.24.-	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g2995.t1 across 39 RNA-seq samples of Acropora digitifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

39Samples

39TPM > 0

1Conditions

59.9Max TPM

24.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Coral branch	39	39	24.17	59.92

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR23047235	Coral branch	Coral branch	adult	not recorded	SRP416931	59.92
SRR23047218	Coral branch	Coral branch	adult	not recorded	SRP416931	59.76
SRR23047209	Coral branch	Coral branch	adult	not recorded	SRP416931	54.10
SRR23047238	Coral branch	Coral branch	adult	not recorded	SRP416931	50.17
SRR23047215	Coral branch	Coral branch	adult	not recorded	SRP416931	48.71
SRR23047232	Coral branch	Coral branch	adult	not recorded	SRP416931	46.83
SRR23047212	Coral branch	Coral branch	adult	not recorded	SRP416931	45.72
SRR23047219	Coral branch	Coral branch	adult	not recorded	SRP416931	43.99
SRR23047211	Coral branch	Coral branch	adult	not recorded	SRP416931	41.43
SRR23047231	Coral branch	Coral branch	adult	not recorded	SRP416931	41.36
SRR23047241	Coral branch	Coral branch	adult	not recorded	SRP416931	39.44
SRR23047228	Coral branch	Coral branch	adult	not recorded	SRP416931	31.79
SRR23047236	Coral branch	Coral branch	adult	not recorded	SRP416931	29.48
SRR23047225	Coral branch	Coral branch	adult	not recorded	SRP416931	29.11
SRR23047237	Coral branch	Coral branch	adult	not recorded	SRP416931	27.31
SRR23047224	Coral branch	Coral branch	adult	not recorded	SRP416931	26.05
SRR23047240	Coral branch	Coral branch	adult	not recorded	SRP416931	19.14
SRR23047214	Coral branch	Coral branch	adult	not recorded	SRP416931	18.44
SRR23047242	Coral branch	Coral branch	adult	not recorded	SRP416931	17.50
SRR23047227	Coral branch	Coral branch	adult	not recorded	SRP416931	17.42
SRR23047208	Coral branch	Coral branch	adult	not recorded	SRP416931	17.40
SRR23047206	Coral branch	Coral branch	adult	not recorded	SRP416931	17.19
SRR23047210	Coral branch	Coral branch	adult	not recorded	SRP416931	15.60
SRR23047230	Coral branch	Coral branch	adult	not recorded	SRP416931	15.26
SRR23047216	Coral branch	Coral branch	adult	not recorded	SRP416931	15.15
SRR23047239	Coral branch	Coral branch	adult	not recorded	SRP416931	15.01
SRR23047217	Coral branch	Coral branch	adult	not recorded	SRP416931	13.06
SRR23047223	Coral branch	Coral branch	adult	not recorded	SRP416931	10.74
SRR23047233	Coral branch	Coral branch	adult	not recorded	SRP416931	9.70
SRR23047222	Coral branch	Coral branch	adult	not recorded	SRP416931	9.58
SRR23047221	Coral branch	Coral branch	adult	not recorded	SRP416931	9.58
SRR23047234	Coral branch	Coral branch	adult	not recorded	SRP416931	8.75
SRR23047213	Coral branch	Coral branch	adult	not recorded	SRP416931	8.70
SRR23047229	Coral branch	Coral branch	adult	not recorded	SRP416931	7.37
SRR23047244	Coral branch	Coral branch	adult	not recorded	SRP416931	6.20
SRR23047207	Coral branch	Coral branch	adult	not recorded	SRP416931	5.97
SRR23047243	Coral branch	Coral branch	adult	not recorded	SRP416931	3.91
SRR23047226	Coral branch	Coral branch	adult	not recorded	SRP416931	3.11
SRR23047220	Coral branch	Coral branch	adult	not recorded	SRP416931	2.58

Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM, StringTie quantification over 39 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.