Gene detail

Detailed information of g30477.t2 in Acropora digitifera

Genomic Location: chr14Alt:19693426...19706340
NR annotation: XP_044163087.1, DNA mismatch repair protein Mlh3-like isoform X2 [Acropora millepora]
Species abbreviation ADIGI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g30477.t2

ATGCGACAGTTCAAATCAAGTGAACACCTGATGTCTTGCGAGCAGCGACAGCGAACAATACGTCCTTTGCAGGAAGACGTGCGTTCAAATTTGAGGTCTGGAGTTGCGATTACGAACTTGACTCAATGTGTAGAGGAACTTGTTTTAAACAGCTTGGATGCTGACTCGACCAGTATCACTGTGCGAATAGATGTCCCAAATTATAAAATTCAAGTCTCTGATAATGGCAATGGAATCGTGTTTGAAGATCTGAAGCGTGTTGGCGAAAGATACATGACCAGTAAATGTCATGCTCTCAAAGACTTGGAAAATTTGAATTTTTTCGGGTTCAGAGGCGAGGCTCTTGCAAATATCAGCAAGATCTGCGATGTACTTGAAATAAGCTCTCGCTACAGGTCTTCATATCAAACGTACTGCAAACTCTTTCAAAATTCGCAAGTCTTAGACCTTGGAGAATCAACATTTCCAAGGACAAGCTCAGGAACAACTGTTACCATTCACAATATATTTGCAAACCTTCCAGTCCGGCAAAACTTGATCACAGAAACCTATGACCTTGATCGCGTACGTCACAGAATTGCATCAATGGCCTTAATTAATCCCAAGACGTCTTTCTTATTGATTAATGATTCAACTGGTGCAAAATGTTTACAAACTAGTGTCTGTAAATCTTCAATTTCAACGTTCTCCCAGCTGTTTGGGAACTCCAGATCCAAAGGTCTACAGAAAGTGCAATTTGAACACAAGAAGTTTAAAGTCTCTGGTTATATTTCCACAGAGTTTCATCATAGTAAGACCCTGCAATTTTTGTTCGTAAACCAACGCCTTCTGTTGAAGACAAAGATTCATAAACTGGTGAATAGTCTTCTTGAAAAATCAGAATTTATGAGAAACCTCATTCCTTGTGATAAATCTCAACTGGGGCCAGACTTGTTTCAGGGTAAAGTCATCAGTCCACAAAATATAAAGACAAATGATAAACATGGTATTTTTTTCCTTAATATTATTTGTCCTGTTACAGACTATGACATTTGTCTTGATCCTGTTAAGACTTTAATTGAATTCCAGTACTGGGATGATGTTTTGTACTGCATGCAAAGATGTGTTGAAGACTTTTGCAATAAAAATAACCTGGTTTTGCAACATGAAAATTCACCCAAATCAACAGGATCTGAAAGAGATGAAAATGATGGATTTGCAGAGGTCTGTTTACATCCATGCCTTGATGCTTTTGCATACAAAAGAGAAATTGAAACTGGTAATGTGAAGAGAAGTTTGCATTCTTCAACTGTTTTCAGGAAAACAAGTGTTGGAATAGCAGACGACAAGAGTCTGCAAATGACATCTAACCATGAAGAAAAATCCCATTTATCTGATCAGAAACAAAAAGAGAATATCATTCAAAATGACATGGCAGGTAATAAAGTTTTCAGTGGTCTAGGAGTATACAAGGATCAAAGTGAATTCAGTCCAAAATCAGTGTCAAAAGAGACTTTACCCTCCTTGAAAAACTCAACCTGTTGCTTGAATGACACAAATATGGAAAAATCATTTGAATGTTCATTTGTCAGAAATCACAGGAATGACGAGAAAGCTGATCCTGGTATCATCACATCTAGCTCAACCACCTTTTCTGCTTCTGAGTCAACCAAGGGCTGTGAAAATTATTCAGCCAAGGTGGGTGACGCACAGGTTAGAACGTCAATGCTTCAAGGATTATCTAACCAAAGAAACACTGATCATGATGGAAGGCCAGTGATTGTTGGTGCATCCAGCTCAAATGCAAAGGAAATGAGATCAAAACATTTAACAACATTCACTTCTCCCTGCCCTATCACACTACAGCCGGCTTATGCAAGAAAGAGACCTTGGATCCATAAAGGGACATCATCAGCAAGTTGTGAGGTATCAAAAGATAGGAGACTGATAAGTTTAAAAGGATCTGTAAAAAGGAGAAACAGAGCTAACAGAGTTCATATGCAGGAATCCTGTGATTTTGACAACAGGGAAGGCAATGCATGCATGGTGGTATGCTGTAACCAAACTGAGGAAACACCAGGATGCAGCACTTTCACAGTCCAAGAAATGACTCCTGGTGCTAGCAAAGAGAACATCGTTACTGGTGATAAAGATACTAATCCTGTACTACACAGGGTTGCCTGTCACACGACTGCTTTGCTTGATTGTGGTGAGCAGTGCACAAATGCTTATGCTGACAGGGCTTGTCTTTCAAATTCTAACAAACTTAAGTCACCCAACAGGGAGACAGAAACGTTTTGTGGTGTTACAGAAAACACTGAACATTGGCAGGGCAGAAATACAGAGCACAATTCAAATCAGTCTTCAGCTTTGTCAGAGACGATGAGAGAAACCTCAGTTGAAGAGAAAACATTTGACAAGCAGGAAAGCAACTCTTGCATAAGAAGTAACTGGCATTGTGCCTTCGACCCATCATTGGGAAGAAATCTCTTTCTTAACATTCGAACTGGACACTCTTCCTATGAACATCCAAGCAGACTAAGTGTTGGAAGTGAAGATTGTTCCTGTGTTAATGAGAATAATGAAGTGGACAATAAGCAACACCAGAATGTACCTCACCCAGTTGCTTCTCACTTGTCATTTTCTTGTACTCCCTGGCTTCCACGGCAACATTGGAGATCACAAATATCTTCTTTTGATGAGGACACAGGCTCCTTTTGTTCAAATGGTGAGTCTGAAGTTGCCATGCTATACCAGGAGCACCAATATAGCCAAGAAACAGAGGAAGAACTCTGCAAATGGGCCAGTGCAGACAAGCTGAAAGCCTACAAACAGAATCTTTGGGACAGTACAGGATCGACTGTGGCAGAAATGCTTGACAATTGGACAAACCCTGTGTTTACAGCACCAGAAAAGGATATTTTGATGGTCAACAAACCAGGCAACTGCGTTAGAAATCAGATACCTATTCATAACATGGTTCAACCGCATCGCTTCACAAGAGACATGTTAGAATCCATGAGAGTATTGCAACAGCTGGATGAAAAGTTTATTGTGGGTGTTGTCTCACACAGAGGCAATGATGATGACTTGCTGGTGTTAATAGATCAGCATGCAGCCCATGAACGTGTGCGATTAGAACAACTTCAGTCAGAACTCTTTGAAAATATTTCAACTGGAAGCAGACCAAGAATCAAGTCTTCCCCTGTCTCCCCACCCATGGAAATATTCTTGTTTGCTGAAGAAATTCGACTTTTGAAGACGTTTCAATCAGAAATCGAGCGTATTGGAATCCATTTTACTATCAATGAGTCGGTGGAAGAGTCTGATGAGGTTTCTGTGGTTATCCAAGCTGTTCCTTCTGTATTTGTGGAACGCGAAGTGTCCGAGGTCAAACGTGGAAGGCAATCTGTCACTGCAAGCAAAGTGAAGGAGCTCATCAGGGAACATCTTGAAATTTTGACGATGCGTGGAACCCCAGCAAATATTCCAAAGAACATTTTTCAAGTGATCAGCTCTCAAGCTTGCCATGGTGCAGTCAAGTTTGGGGAGCCTCTTGGAGTCAATGAGTGTCAGCAGCTTGTTATGAATTTATCCAAATGCCACTTACCTTTTCAATGCGCCCACGGAAGACCCTCTGTCATTCCATTGGCCGACCTTAGGATTTTGGGAAGAAAAATGGTATCGCAGGATATCGAAAGGCGCCCAAGATTGGATAAGCTACACTATCTGATAAACAAGAAACTGTAA

Transcript

chr14Alt.g30477.t2

AATTTAGTTTTGGTGCAAAATTTTTAAAACTGGTTCAATTTTTATTTTCTTTTGTTTTATATTCATTACCATGGTCTGGAACAATGATAAATTGAATTTCCAAGTCAACAATGCGACAGTTCAAATCAAGTGAACACCTGATGTCTTGCGAGCAGCGACAGCGAACAATACGTCCTTTGCAGGAAGACGTGCGTTCAAATTTGAGGTCTGGAGTTGCGATTACGAACTTGACTCAATGTGTAGAGGAACTTGTTTTAAACAGCTTGGATGCTGACTCGACCAGTATCACTGTGCGAATAGATGTCCCAAATTATAAAATTCAAGTCTCTGATAATGGCAATGGAATCGTGTTTGAAGATCTGAAGCGTGTTGGCGAAAGATACATGACCAGTAAATGTCATGCTCTCAAAGACTTGGAAAATTTGAATTTTTTCGGGTTCAGAGGCGAGGCTCTTGCAAATATCAGCAAGATCTGCGATGTACTTGAAATAAGCTCTCGCTACAGGTCTTCATATCAAACGTACTGCAAACTCTTTCAAAATTCGCAAGTCTTAGACCTTGGAGAATCAACATTTCCAAGGACAAGCTCAGGAACAACTGTTACCATTCACAATATATTTGCAAACCTTCCAGTCCGGCAAAACTTGATCACAGAAACCTATGACCTTGATCGCGTACGTCACAGAATTGCATCAATGGCCTTAATTAATCCCAAGACGTCTTTCTTATTGATTAATGATTCAACTGGTGCAAAATGTTTACAAACTAGTGTCTGTAAATCTTCAATTTCAACGTTCTCCCAGCTGTTTGGGAACTCCAGATCCAAAGGTCTACAGAAAGTGCAATTTGAACACAAGAAGTTTAAAGTCTCTGGTTATATTTCCACAGAGTTTCATCATAGTAAGACCCTGCAATTTTTGTTCGTAAACCAACGCCTTCTGTTGAAGACAAAGATTCATAAACTGGTGAATAGTCTTCTTGAAAAATCAGAATTTATGAGAAACCTCATTCCTTGTGATAAATCTCAACTGGGGCCAGACTTGTTTCAGGGTAAAGTCATCAGTCCACAAAATATAAAGACAAATGATAAACATGGTATTTTTTTCCTTAATATTATTTGTCCTGTTACAGACTATGACATTTGTCTTGATCCTGTTAAGACTTTAATTGAATTCCAGTACTGGGATGATGTTTTGTACTGCATGCAAAGATGTGTTGAAGACTTTTGCAATAAAAATAACCTGGTTTTGCAACATGAAAATTCACCCAAATCAACAGGATCTGAAAGAGATGAAAATGATGGATTTGCAGAGGTCTGTTTACATCCATGCCTTGATGCTTTTGCATACAAAAGAGAAATTGAAACTGGTAATGTGAAGAGAAGTTTGCATTCTTCAACTGTTTTCAGGAAAACAAGTGTTGGAATAGCAGACGACAAGAGTCTGCAAATGACATCTAACCATGAAGAAAAATCCCATTTATCTGATCAGAAACAAAAAGAGAATATCATTCAAAATGACATGGCAGGTAATAAAGTTTTCAGTGGTCTAGGAGTATACAAGGATCAAAGTGAATTCAGTCCAAAATCAGTGTCAAAAGAGACTTTACCCTCCTTGAAAAACTCAACCTGTTGCTTGAATGACACAAATATGGAAAAATCATTTGAATGTTCATTTGTCAGAAATCACAGGAATGACGAGAAAGCTGATCCTGGTATCATCACATCTAGCTCAACCACCTTTTCTGCTTCTGAGTCAACCAAGGGCTGTGAAAATTATTCAGCCAAGGTGGGTGACGCACAGGTTAGAACGTCAATGCTTCAAGGATTATCTAACCAAAGAAACACTGATCATGATGGAAGGCCAGTGATTGTTGGTGCATCCAGCTCAAATGCAAAGGAAATGAGATCAAAACATTTAACAACATTCACTTCTCCCTGCCCTATCACACTACAGCCGGCTTATGCAAGAAAGAGACCTTGGATCCATAAAGGGACATCATCAGCAAGTTGTGAGGTATCAAAAGATAGGAGACTGATAAGTTTAAAAGGATCTGTAAAAAGGAGAAACAGAGCTAACAGAGTTCATATGCAGGAATCCTGTGATTTTGACAACAGGGAAGGCAATGCATGCATGGTGGTATGCTGTAACCAAACTGAGGAAACACCAGGATGCAGCACTTTCACAGTCCAAGAAATGACTCCTGGTGCTAGCAAAGAGAACATCGTTACTGGTGATAAAGATACTAATCCTGTACTACACAGGGTTGCCTGTCACACGACTGCTTTGCTTGATTGTGGTGAGCAGTGCACAAATGCTTATGCTGACAGGGCTTGTCTTTCAAATTCTAACAAACTTAAGTCACCCAACAGGGAGACAGAAACGTTTTGTGGTGTTACAGAAAACACTGAACATTGGCAGGGCAGAAATACAGAGCACAATTCAAATCAGTCTTCAGCTTTGTCAGAGACGATGAGAGAAACCTCAGTTGAAGAGAAAACATTTGACAAGCAGGAAAGCAACTCTTGCATAAGAAGTAACTGGCATTGTGCCTTCGACCCATCATTGGGAAGAAATCTCTTTCTTAACATTCGAACTGGACACTCTTCCTATGAACATCCAAGCAGACTAAGTGTTGGAAGTGAAGATTGTTCCTGTGTTAATGAGAATAATGAAGTGGACAATAAGCAACACCAGAATGTACCTCACCCAGTTGCTTCTCACTTGTCATTTTCTTGTACTCCCTGGCTTCCACGGCAACATTGGAGATCACAAATATCTTCTTTTGATGAGGACACAGGCTCCTTTTGTTCAAATGGTGAGTCTGAAGTTGCCATGCTATACCAGGAGCACCAATATAGCCAAGAAACAGAGGAAGAACTCTGCAAATGGGCCAGTGCAGACAAGCTGAAAGCCTACAAACAGAATCTTTGGGACAGTACAGGATCGACTGTGGCAGAAATGCTTGACAATTGGACAAACCCTGTGTTTACAGCACCAGAAAAGGATATTTTGATGGTCAACAAACCAGGCAACTGCGTTAGAAATCAGATACCTATTCATAACATGGTTCAACCGCATCGCTTCACAAGAGACATGTTAGAATCCATGAGAGTATTGCAACAGCTGGATGAAAAGTTTATTGTGGGTGTTGTCTCACACAGAGGCAATGATGATGACTTGCTGGTGTTAATAGATCAGCATGCAGCCCATGAACGTGTGCGATTAGAACAACTTCAGTCAGAACTCTTTGAAAATATTTCAACTGGAAGCAGACCAAGAATCAAGTCTTCCCCTGTCTCCCCACCCATGGAAATATTCTTGTTTGCTGAAGAAATTCGACTTTTGAAGACGTTTCAATCAGAAATCGAGCGTATTGGAATCCATTTTACTATCAATGAGTCGGTGGAAGAGTCTGATGAGGTTTCTGTGGTTATCCAAGCTGTTCCTTCTGTATTTGTGGAACGCGAAGTGTCCGAGGTCAAACGTGGAAGGCAATCTGTCACTGCAAGCAAAGTGAAGGAGCTCATCAGGGAACATCTTGAAATTTTGACGATGCGTGGAACCCCAGCAAATATTCCAAAGAACATTTTTCAAGTGATCAGCTCTCAAGCTTGCCATGGTGCAGTCAAGTTTGGGGAGCCTCTTGGAGTCAATGAGTGTCAGCAGCTTGTTATGAATTTATCCAAATGCCACTTACCTTTTCAATGCGCCCACGGAAGACCCTCTGTCATTCCATTGGCCGACCTTAGGATTTTGGGAAGAAAAATGGTATCGCAGGATATCGAAAGGCGCCCAAGATTGGATAAGCTACACTATCTGATAAACAAGAAACTGTAACTTTTGTGGTGACTTTTGGGAAACTGG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9UHC1	DNA mismatch repair protein Mlh3 OS=Homo sapiens OX=9606 GN=MLH3 PE=1 SV=3
F4JN26	DNA mismatch repair protein MLH3 OS=Arabidopsis thaliana OX=3702 GN=MLH3 PE=2 SV=2
Q12083	DNA mismatch repair protein MLH3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MLH3 PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08676 all species →	MutL_C	MutL C terminal dimerisation domain	Domain	Interproscan
PF13589 all species →	HATPase_c_3	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	Domain	Interproscan
PF01119 all species →	DNA_mis_repair	DNA mismatch repair protein, C-terminal domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014790 all species →	Domain	MutL, C-terminal, dimerisation	Interproscan
IPR014721 all species →	Homologous_superfamily	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Interproscan
IPR038973 all species →	Family	DNA mismatch repair protein MutL/Mlh/Pms-like	Interproscan
IPR042121 all species →	Homologous_superfamily	MutL, C-terminal domain, regulatory subdomain	Interproscan
IPR014762 all species →	Conserved_site	DNA mismatch repair, conserved site	Interproscan
IPR042120 all species →	Homologous_superfamily	MutL, C-terminal domain, dimerisation subdomain	Interproscan
IPR013507 all species →	Domain	DNA mismatch repair protein, S5 domain 2-like	Interproscan
IPR036890 all species →	Homologous_superfamily	Histidine kinase/HSP90-like ATPase superfamily	Interproscan
IPR002099 all species →	Family	DNA mismatch repair protein MutL/Mlh/PMS	Interproscan
IPR037198 all species →	Homologous_superfamily	MutL, C-terminal domain superfamily	Interproscan
IPR020568 all species →	Homologous_superfamily	Ribosomal protein uS5 domain 2-type superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10073 all species →	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006298 all species →	Biological Process	mismatch repair	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0032300 all species →	Cellular Component	mismatch repair complex	Interproscan
GO:0140664 all species →	Molecular Function	ATP-dependent DNA damage sensor activity	Interproscan
GO:0030983 all species →	Molecular Function	mismatched DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08739	MLH3; DNA mismatch repair protein MLH3	-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.