Genomic Location: chr14Alt:22625999...22631905
NR annotation: XP_029207699.2, CDK-activating kinase assembly factor MAT1-like [Acropora millepora]
Species Acropora digitifera · all data for this species · gene families
| CDS |
| g30730.t1 |
| Transcript |
| chr14Alt.g30730.t1 |
| Protein |
| chr14Alt.g30730.t1 |
| UniProt accession | Description |
|---|---|
| P51949 | CDK-activating kinase assembly factor MAT1 OS=Mus musculus OX=10090 GN=Mnat1 PE=1 SV=2 |
| P51950 | CDK-activating kinase assembly factor MAT1 OS=Marthasterias glacialis OX=7609 PE=1 SV=1 |
| P51948 | CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06391 all species → | MAT1 | CDK-activating kinase assembly factor MAT1 | Family | Interproscan |
| PF17121 all species → | zf-C3HC4_5 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001841 all species → | Domain | Zinc finger, RING-type | Interproscan |
| IPR017907 all species → | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR015877 all species → | Domain | Cdk-activating kinase assembly factor MAT1, centre | Interproscan |
| IPR004575 all species → | Family | Cdk-activating kinase assembly factor MAT1/Tfb3 | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12683 all species → | CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000079 all species → | Biological Process | regulation of cyclin-dependent protein serine/threonine kinase activity | Interproscan |
| GO:0005675 all species → | Cellular Component | transcription factor TFIIH holo complex | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0006357 all species → | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0006289 all species → | Biological Process | nucleotide-excision repair | Interproscan |
| GO:0045737 all species → | Biological Process | positive regulation of cyclin-dependent protein serine/threonine kinase activity | Interproscan |
| GO:0061575 all species → | Molecular Function | cyclin-dependent protein serine/threonine kinase activator activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10842 | MNAT1; CDK-activating kinase assembly factor MAT1 | - | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of g30730.t1 across 39 RNA-seq samples of Acropora digitifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Coral branch | 39 | 39 | 28.11 | 38.49 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR23047224 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 38.49 |
| SRR23047240 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 38.27 |
| SRR23047217 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 34.47 |
| SRR23047208 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 33.59 |
| SRR23047214 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 33.42 |
| SRR23047210 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 32.51 |
| SRR23047244 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 31.40 |
| SRR23047237 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 31.36 |
| SRR23047228 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 30.81 |
| SRR23047206 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 30.52 |
| SRR23047209 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 30.32 |
| SRR23047222 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 30.24 |
| SRR23047216 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 29.91 |
| SRR23047223 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 29.86 |
| SRR23047238 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 29.67 |
| SRR23047230 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 29.22 |
| SRR23047219 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 28.82 |
| SRR23047227 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 28.59 |
| SRR23047235 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 28.56 |
| SRR23047239 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 28.19 |
| SRR23047212 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 28.01 |
| SRR23047236 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 27.64 |
| SRR23047229 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 27.45 |
| SRR23047241 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 27.37 |
| SRR23047243 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 27.18 |
| SRR23047225 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 27.05 |
| SRR23047242 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 26.84 |
| SRR23047215 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 26.17 |
| SRR23047232 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 26.08 |
| SRR23047213 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 25.84 |
| SRR23047231 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 25.73 |
| SRR23047218 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 25.14 |
| SRR23047233 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 24.86 |
| SRR23047234 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 24.53 |
| SRR23047220 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 23.98 |
| SRR23047211 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 22.29 |
| SRR23047226 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 21.37 |
| SRR23047207 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 16.71 |
| SRR23047221 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 13.98 |
Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM,
StringTie quantification over 39 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora digitifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 1 | g9067.t1 | 0.705871173612441 |
| Negatively correlated | 122 | g23965.t1 | -0.704487948702139 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora digitifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 1 available assay. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: DNase-seq (DHS).
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |