Gene detail

Detailed information of g31.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: NQZ13378.1, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC [Alphaproteobacteria bacterium]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5E8M6	Coenzyme A biosynthesis bifunctional protein CoaBC OS=Aliivibrio fischeri (strain ATCC 700601 / ES114) OX=312309 GN=coaBC PE=3 SV=1
P44953	Coenzyme A biosynthesis bifunctional protein CoaBC OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=coaBC PE=3 SV=1
Q8DDX8	Coenzyme A biosynthesis bifunctional protein CoaBC OS=Vibrio vulnificus (strain CMCP6) OX=216895 GN=coaBC PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000000 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000022 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000049 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001532 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0005877 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0006122 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0006635 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0007050 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0008327 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0009665 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0016591 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0061639 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0061733 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02046 all species →	COX6A	Cytochrome c oxidase subunit VIa	Family	Interproscan
PF01398 all species →	JAB	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	Family	Interproscan
PF00076 all species →	RRM_1	RNA recognition motif	Domain	Interproscan
PF13865 all species →	FoP_duplication	C-terminal duplication domain of Friend of PRMT1	Family	Interproscan
PF12706 all species →	Lactamase_B_2	Beta-lactamase superfamily domain	Domain	Interproscan
PF04127 all species →	DFP	DNA / pantothenate metabolism flavoprotein	Family	Interproscan
PF02441 all species →	Flavoprotein	Flavoprotein	Family	Interproscan
PF13499 all species →	EF-hand_7	EF-hand domain pair	Domain	Interproscan
PF20700 all species →	Mutator	Mutator-like transposase	Domain	Interproscan
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001349 all species →	Family	Cytochrome c oxidase, subunit VIa	Interproscan
IPR036418 all species →	Homologous_superfamily	Cytochrome c oxidase, subunit VIa superfamily	Interproscan
IPR037518 all species →	Domain	MPN domain	Interproscan
IPR000555 all species →	Domain	JAB1/MPN/MOV34 metalloenzyme domain	Interproscan
IPR000504 all species →	Domain	RNA recognition motif domain	Interproscan
IPR025715 all species →	Domain	Chromatin target of PRMT1 protein, C-terminal	Interproscan
IPR012677 all species →	Homologous_superfamily	Nucleotide-binding alpha-beta plait domain superfamily	Interproscan
IPR035979 all species →	Homologous_superfamily	RNA-binding domain superfamily	Interproscan
IPR051229 all species →	Family	ALYREF mRNA export adapter	Interproscan
IPR043128 all species →	Homologous_superfamily	Reverse transcriptase/Diguanylate cyclase domain	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR001584 all species →	Domain	Integrase, catalytic core	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR036866 all species →	Homologous_superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like	Interproscan
IPR024884 all species →	Family	N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D	Interproscan
IPR001279 all species →	Domain	Metallo-beta-lactamase	Interproscan
IPR035929 all species →	Homologous_superfamily	CoaB-like superfamily	Interproscan
IPR036551 all species →	Homologous_superfamily	Flavin prenyltransferase-like	Interproscan
IPR007085 all species →	Domain	DNA/pantothenate metabolism flavoprotein, C-terminal	Interproscan
IPR005252 all species →	Family	Coenzyme A biosynthesis bifunctional protein CoaBC	Interproscan
IPR003382 all species →	Domain	Flavoprotein	Interproscan
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR043520 all species →	Family	Spermatogenesis-associated protein 21	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR001751 all species →	Conserved_site	S100/Calcium binding protein 7/8-like, conserved site	Interproscan
IPR049012 all species →	Domain	Mutator-like transposase domain	Interproscan
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR051342 all species →	Family	PDZ domain-containing scaffold protein	Interproscan
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11504 all species →	CYTOCHROME C OXIDASE POLYPEPTIDE VIA	Interproscan
PTHR10540 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED	Interproscan
PTHR19965 all species →	RNA AND EXPORT FACTOR BINDING PROTEIN	Interproscan
PTHR47331 all species →	PHD-TYPE DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR46704 all species →	CXC DOMAIN-CONTAINING PROTEIN-RELATED	Interproscan
PTHR15032 all species →	N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D	Interproscan
PTHR14359 all species →	HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY	Interproscan
PTHR47500 all species →	EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR19964 all species →	MULTIPLE PDZ DOMAIN PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005743 all species →	Cellular Component	mitochondrial inner membrane	Interproscan
GO:0005751 all species →	Cellular Component	obsolete mitochondrial respiratory chain complex IV	Interproscan
GO:0006123 all species →	Biological Process	mitochondrial electron transport, cytochrome c to oxygen	Interproscan
GO:0030234 all species →	Molecular Function	enzyme regulator activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0008233 all species →	Molecular Function	peptidase activity	Interproscan
GO:0008237 all species →	Molecular Function	metallopeptidase activity	Interproscan
GO:0003743 all species →	Molecular Function	translation initiation factor activity	Interproscan
GO:0006413 all species →	Biological Process	translational initiation	Interproscan
GO:0031369 all species →	Molecular Function	translation initiation factor binding	Interproscan
GO:0071541 all species →	Cellular Component	eukaryotic translation initiation factor 3 complex, eIF3m	Interproscan
GO:0003723 all species →	Molecular Function	RNA binding	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0003729 all species →	Molecular Function	mRNA binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006406 all species →	Biological Process	mRNA export from nucleus	Interproscan
GO:0015074 all species →	Biological Process	DNA integration	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0070290 all species →	Molecular Function	N-acylphosphatidylethanolamine-specific phospholipase D activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0043227 all species →	Cellular Component	membrane-bounded organelle	Interproscan
GO:0070291 all species →	Biological Process	N-acylethanolamine metabolic process	Interproscan
GO:0070292 all species →	Biological Process	N-acylphosphatidylethanolamine metabolic process	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0004633 all species →	Molecular Function	phosphopantothenoylcysteine decarboxylase activity	Interproscan
GO:0010181 all species →	Molecular Function	FMN binding	Interproscan
GO:0015937 all species →	Biological Process	coenzyme A biosynthetic process	Interproscan
GO:0071513 all species →	Cellular Component	phosphopantothenoylcysteine decarboxylase complex	Interproscan
GO:0004632 all species →	Molecular Function	phosphopantothenate--cysteine ligase activity	Interproscan
GO:0015941 all species →	Biological Process	pantothenate catabolic process	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02266	COX6A; cytochrome c oxidase subunit 6a	-	Non-alcoholic fatty liver disease	ko04932	deepkoala
K12881	THOC4, ALY; THO complex subunit 4	-	Spliceosome	ko03041	deepkoala
K13038	coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase	EC:4.1.1.36 EC:6.3.2.5	Pantothenate and CoA biosynthesis	ko00770	deepkoala
K13985	NAPEPLD; N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D	EC:3.1.4.54	Retrograde endocannabinoid signaling	ko04723	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →