Gene detail

Detailed information of g3522.t2 in Acropora digitifera

Genomic Location: chr2Alt:14163499...14189006
NR annotation: XP_015763189.1, PREDICTED: E3 ubiquitin-protein ligase NEDD4-like [Acropora digitifera]
Species Acropora digitifera · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g3522.t2

ATGAATTCGCCATCAGTCGGTCCACCGGTCGTCCATGGTTTAAAACCTTCAAGAGATTCCAGCCTCAAGATTGTACGAGTAGTTGTTATTAAGGGAACTGATTTGGCCAAGAAGGATATATTTGGATTGAGTGACCCTTACTGCAAAATAAAATTATTTCAAGGAGATAGAGAATATGGAGAAATTGATTCAGTTGTTACTGACACCATTAAAAAGACATTACATCCACAATGGAATGAAGAATTTTTCTTTAGGGTGAACCAAAGTGTTAATAGACTTTTGTTTGAGGTGTTTGATGAAAACAGACTCACTAGAGATGACTTTCTTGGTGAGGTGGAACTACGCCTGTTCTCTTTACCGACTGAGGGGCCAAATGTCACCATCCATGCAGGAAATTATATGCTGAGGCCAAGAAGTAGCAAATCTCGAGTGAGTGGCAACTTGCAGTTACGGCTGTCGTTTCTCTCGCCCGATGATGCTCCTCAGACAGGAACTTCTGTTCCTTCGTCACCACCACGGCCCGATGCTGCAGCCTTGAGTGTTATTGACGAACCAGCGCCATCTTCACCTATGCAAGTTGAGTCACTTTCTGGTGATGAAGAACCTTCCAGGGCCACAACACGTCCTCAGGAGGCCCTCCCTGCGGGTTGGGAGGAAAGACAGGATGCTAACGGAAGAACATTTTTCATTGACCATTCCACAAGAACAACTTCCTGGGTTAGGCCGACAGGACAGAGTAATACAACACATCAACATGAAATTCAAGAAAATGATGCCAGGAGAGAAAGAAACTTTAGAATTCGTCGCCACCTGAGTATTGATGGGAGTGCAACATCATCGACGGAGAACACAGGAACCAGTAACCAGGCTAGCTCAGAGGCGGAAGAATTGCTGCCCCCAGGCTGGGCTATGCAGAGGGCGCCAAATGGTAGAATGTTCTTCATCGACCACAACAGTAGAAAAACGACCTGGCGTGACCCTCGGATCCATCATCATCCAAGTCTCAGTTCCAGCCCATCAATGTCTCCAGAAATCGGAAGATCGGCGCGTCTGTCTCACGCTGATCTTGGACCTTTACCAGACGGCTGGGAAGAAAGAGTTCATACAGATGGAAGGGTCTTTTATATTGACCATGAGACCAAGTCAACTCAATGGGACGACCCTCGAATTCAGATCAATAATAAGCCGTCTCAGGCGGTTCCGTATTCCAGAGACTTCAAACGCAAGTGCGACTACTTCAGATCGAAGCTCAAAAGACCGGTAAATGTTCCAAATAAGTACGAAATCCACGTAAGAAGAAACAACCTTTTACTAGATTCATACCGAGGCGTGCATCCTGTGTCTAACCCTGAACTCCTTAAGACAAGGCTTTGGATTGTTTTTGATGGAGAAACTGGCCTGGATTATGGTGGAGTACAGAGAGAGTGGTTCTATTTACTCTCCAAAGAAGTCTTCAATCCTTACTATGGCTTGTTTGAGTACTCTGCAAGCGATAATTACACGCTTCAAATTAACCCCAACTCAGGAATGTGTAACGAAGACCATTTATTGTACTTCAAGTTTATTGGGCGGCTGGCTGGAATGGCTGTGTATCATGGCAAACTCCTGGATGCGTTTTTCATTCGTCCATTTTATAAGATGATGTTGGGAAAGCCCATCACACTGATTGACATGGAAAGTGTGGATTCCGAATACTATAACAGTTTGAATTGGATTTTGGAGAATGATCCTGAAGATTTAGATCTGACTTTCTGTGTCGATGAGGAGTTGTTTGGACAGGTGACAGTGAAAGATCTTAAATCACGTGGATCAGAAATCAAGGTCACAAATGCCAACAAGAGGGAATATATCAATCTTGTAATCAAGTGGAGGTTTGTGAGCAGAGTCGAGGACCAGATGAAGAAGTTCATGGAAGGTTTTAGCGAACTCATACCACATAATTTGATACAGATATTCGATGAAAGGGAACTAGAGCTTCTTATGTGTGGCCTTGGAGAGATTGACATCAATGACTGGCGTAAACATACAAATTACCGTGGAGAATATGGTGATAAACACCACGTGATTGTCTGGTTTTGGAAGGCTTTGAGCTCGTTTGATCTGGAAACTCGCGCCAGGCTTTTGCAGTTCGTGACCGGAACTTCACGAGTACCTATGAACGGATTTGCCGAATTATATGGCAGCAATGGGCCTCAGAGATTCACCATTGAGCCCTGGGGCACTCCGCATTCCTTACCAAGGGCTCACACTTGCTTCAACAGACTGGACCTTCCTCGCTACAGAACCTACTATGAGTTGAGAGAAAAACTACGATTAGCCATTGAAAACACACAAGGCTTTGAAGGAGTAGATTAG

Transcript

chr2Alt.g3522.t2

ATTGGACCGAGCTAACACTGTTAAAAATAAATATGGCCGCATATAAACGGTGGCAGACGTAAGTCTCCCTAATTTGTAGTAGGCATGAATTCGCCATCAGTCGGTCCACCGGTCGTCCATGGTTTAAAACCTTCAAGAGATTCCAGCCTCAAGATTGTACGAGTAGTTGTTATTAAGGGAACTGATTTGGCCAAGAAGGATATATTTGGATTGAGTGACCCTTACTGCAAAATAAAATTATTTCAAGGAGATAGAGAATATGGAGAAATTGATTCAGTTGTTACTGACACCATTAAAAAGACATTACATCCACAATGGAATGAAGAATTTTTCTTTAGGGTGAACCAAAGTGTTAATAGACTTTTGTTTGAGGTGTTTGATGAAAACAGACTCACTAGAGATGACTTTCTTGGTGAGGTGGAACTACGCCTGTTCTCTTTACCGACTGAGGGGCCAAATGTCACCATCCATGCAGGAAATTATATGCTGAGGCCAAGAAGTAGCAAATCTCGAGTGAGTGGCAACTTGCAGTTACGGCTGTCGTTTCTCTCGCCCGATGATGCTCCTCAGACAGGAACTTCTGTTCCTTCGTCACCACCACGGCCCGATGCTGCAGCCTTGAGTGTTATTGACGAACCAGCGCCATCTTCACCTATGCAAGTTGAGTCACTTTCTGGTGATGAAGAACCTTCCAGGGCCACAACACGTCCTCAGGAGGCCCTCCCTGCGGGTTGGGAGGAAAGACAGGATGCTAACGGAAGAACATTTTTCATTGACCATTCCACAAGAACAACTTCCTGGGTTAGGCCGACAGGACAGAGTAATACAACACATCAACATGAAATTCAAGAAAATGATGCCAGGAGAGAAAGAAACTTTAGAATTCGTCGCCACCTGAGTATTGATGGGAGTGCAACATCATCGACGGAGAACACAGGAACCAGTAACCAGGCTAGCTCAGAGGCGGAAGAATTGCTGCCCCCAGGCTGGGCTATGCAGAGGGCGCCAAATGGTAGAATGTTCTTCATCGACCACAACAGTAGAAAAACGACCTGGCGTGACCCTCGGATCCATCATCATCCAAGTCTCAGTTCCAGCCCATCAATGTCTCCAGAAATCGGAAGATCGGCGCGTCTGTCTCACGCTGATCTTGGACCTTTACCAGACGGCTGGGAAGAAAGAGTTCATACAGATGGAAGGGTCTTTTATATTGACCATGAGACCAAGTCAACTCAATGGGACGACCCTCGAATTCAGATCAATAATAAGCCGTCTCAGGCGGTTCCGTATTCCAGAGACTTCAAACGCAAGTGCGACTACTTCAGATCGAAGCTCAAAAGACCGGTAAATGTTCCAAATAAGTACGAAATCCACGTAAGAAGAAACAACCTTTTACTAGATTCATACCGAGGCGTGCATCCTGTGTCTAACCCTGAACTCCTTAAGACAAGGCTTTGGATTGTTTTTGATGGAGAAACTGGCCTGGATTATGGTGGAGTACAGAGAGAGTGGTTCTATTTACTCTCCAAAGAAGTCTTCAATCCTTACTATGGCTTGTTTGAGTACTCTGCAAGCGATAATTACACGCTTCAAATTAACCCCAACTCAGGAATGTGTAACGAAGACCATTTATTGTACTTCAAGTTTATTGGGCGGCTGGCTGGAATGGCTGTGTATCATGGCAAACTCCTGGATGCGTTTTTCATTCGTCCATTTTATAAGATGATGTTGGGAAAGCCCATCACACTGATTGACATGGAAAGTGTGGATTCCGAATACTATAACAGTTTGAATTGGATTTTGGAGAATGATCCTGAAGATTTAGATCTGACTTTCTGTGTCGATGAGGAGTTGTTTGGACAGGTGACAGTGAAAGATCTTAAATCACGTGGATCAGAAATCAAGGTCACAAATGCCAACAAGAGGGAATATATCAATCTTGTAATCAAGTGGAGGTTTGTGAGCAGAGTCGAGGACCAGATGAAGAAGTTCATGGAAGGTTTTAGCGAACTCATACCACATAATTTGATACAGATATTCGATGAAAGGGAACTAGAGCTTCTTATGTGTGGCCTTGGAGAGATTGACATCAATGACTGGCGTAAACATACAAATTACCGTGGAGAATATGGTGATAAACACCACGTGATTGTCTGGTTTTGGAAGGCTTTGAGCTCGTTTGATCTGGAAACTCGCGCCAGGCTTTTGCAGTTCGTGACCGGAACTTCACGAGTACCTATGAACGGATTTGCCGAATTATATGGCAGCAATGGGCCTCAGAGATTCACCATTGAGCCCTGGGGCACTCCGCATTCCTTACCAAGGGCTCACACTTGCTTCAACAGACTGGACCTTCCTCGCTACAGAACCTACTATGAGTTGAGAGAAAAACTACGATTAGCCATTGAAAACACACAAGGCTTTGAAGGAGTAGATTAGCAAGCATACTCTGTTTTGGAAAAAAAAAACTGCGTTTACTCAATTATGTGCAAGGATTTTTAGCATAATATGGAAAGTGAATTAAGAAATGTGAAATGACCTA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q96PU5	E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens OX=9606 GN=NEDD4L PE=1 SV=2
Q5RBF2	E3 ubiquitin-protein ligase NEDD4-like OS=Pongo abelii OX=9601 GN=NEDD4L PE=2 SV=1
Q8CFI0	E3 ubiquitin-protein ligase NEDD4-like OS=Mus musculus OX=10090 GN=Nedd4l PE=1 SV=2

Gene family

Family type	Membership / link
Ubiquitin family	E3\|E3 activity\|HECT · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00397 all species →	WW	WW domain	Domain	Interproscan
PF00168 all species →	C2	C2 domain	Domain	Interproscan
PF00632 all species →	HECT	HECT-domain (ubiquitin-transferase)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001202 all species →	Domain	WW domain	Interproscan
IPR050409 all species →	Family	E3 ubiquitin-protein ligase	Interproscan
IPR000569 all species →	Domain	HECT domain	Interproscan
IPR000008 all species →	Domain	C2 domain	Interproscan
IPR036020 all species →	Homologous_superfamily	WW domain superfamily	Interproscan
IPR035983 all species →	Homologous_superfamily	HECT, E3 ligase catalytic domain	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR024928 all species →	Family	E3 ubiquitin-protein ligase, SMURF1 type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11254 all species →	HECT DOMAIN UBIQUITIN-PROTEIN LIGASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000209 all species →	Biological Process	protein polyubiquitination	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0016567 all species →	Biological Process	protein ubiquitination	Interproscan
GO:0048814 all species →	Biological Process	regulation of dendrite morphogenesis	Interproscan
GO:0061630 all species →	Molecular Function	ubiquitin protein ligase activity	Interproscan
GO:2000650 all species →	Biological Process	negative regulation of sodium ion transmembrane transporter activity	Interproscan
GO:0004842 all species →	Molecular Function	ubiquitin-protein transferase activity	Interproscan
GO:0006511 all species →	Biological Process	ubiquitin-dependent protein catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10591	NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4	EC:2.3.2.26	Mitochondrial biogenesis	ko03029	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g3522.t2 across 39 RNA-seq samples of Acropora digitifera. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

39Samples

0TPM > 0

1Conditions

0.0Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Coral branch	39	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study
SRR23047206	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047207	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047208	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047209	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047210	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047211	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047212	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047213	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047214	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047215	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047216	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047217	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047218	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047219	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047220	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047221	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047222	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047223	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047224	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047225	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047226	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047227	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047228	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047229	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047230	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047231	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047232	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047233	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047234	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047235	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047236	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047237	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047238	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047239	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047240	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047241	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047242	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047243	Coral branch	Coral branch	adult	not recorded	SRP416931
SRR23047244	Coral branch	Coral branch	adult	not recorded	SRP416931

Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM, StringTie quantification over 39 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.