Genomic Location: :...
NR annotation: XP_048585706.1, methionine synthase [Nematostella vectensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q9Z2Q4 | Methionine synthase OS=Rattus norvegicus OX=10116 GN=Mtr PE=1 SV=1 | ||||
| A6H5Y3 | Methionine synthase OS=Mus musculus OX=10090 GN=Mtr PE=1 SV=1 | ||||
| Q4JIJ3 | Methionine synthase OS=Bos taurus OX=9913 GN=MTR PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Alpha-Helix|GAT |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02628 | COX15-CtaA | Cytochrome oxidase assembly protein | Family | Interproscan |
| PF00435 | Spectrin | Spectrin repeat | Domain | Interproscan |
| PF15410 | PH_9 | Pleckstrin homology domain | Domain | Interproscan |
| PF01019 | G_glu_transpept | Gamma-glutamyltranspeptidase | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF03127 | GAT | GAT domain | Domain | Interproscan |
| PF01612 | DNA_pol_A_exo1 | 3'-5' exonuclease | Domain | Interproscan |
| PF00570 | HRDC | HRDC domain | Domain | Interproscan |
| PF01428 | zf-AN1 | AN1-like Zinc finger | Family | Interproscan |
| PF02574 | S-methyl_trans | Homocysteine S-methyltransferase | Family | Interproscan |
| PF02607 | B12-binding_2 | B12 binding domain | Domain | Interproscan |
| PF02310 | B12-binding | B12 binding domain | Domain | Interproscan |
| PF02965 | Met_synt_B12 | Vitamin B12 dependent methionine synthase, activation domain | Domain | Interproscan |
| PF00809 | Pterin_bind | Pterin binding enzyme | Domain | Interproscan |
| PF00005 | ABC_tran | ABC transporter | Domain | Interproscan |
| PF00664 | ABC_membrane | ABC transporter transmembrane region | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018159 | Repeat | Spectrin/alpha-actinin | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR003780 | Family | COX15/CtaA family | Interproscan |
| IPR002017 | Repeat | Spectrin repeat | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001605 | Domain | Pleckstrin homology domain, spectrin-type | Interproscan |
| IPR041681 | Domain | Pleckstrin homology domain 9 | Interproscan |
| IPR043138 | Homologous_superfamily | Gamma-glutamyltranspeptidase, large subunit, C-terminal domain | Interproscan |
| IPR043137 | Homologous_superfamily | Gamma-glutamyltranspeptidase, small subunit | Interproscan |
| IPR000101 | Family | Gamma-glutamyltranspeptidase | Interproscan |
| IPR029055 | Homologous_superfamily | Nucleophile aminohydrolases, N-terminal | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR038425 | Homologous_superfamily | GAT domain superfamily | Interproscan |
| IPR004152 | Domain | GAT domain | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR010997 | Homologous_superfamily | HRDC-like superfamily | Interproscan |
| IPR002562 | Domain | 3'-5' exonuclease domain | Interproscan |
| IPR044876 | Homologous_superfamily | HRDC domain superfamily | Interproscan |
| IPR051086 | Family | Ribonuclease D-like | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR002121 | Domain | HRDC domain | Interproscan |
| IPR000058 | Domain | Zinc finger, AN1-type | Interproscan |
| IPR035896 | Homologous_superfamily | AN1-like Zinc finger | Interproscan |
| IPR053061 | Family | AN1-type zinc finger domain-containing protein | Interproscan |
| IPR004223 | Domain | Vitamin B12-dependent methionine synthase, activation domain | Interproscan |
| IPR006158 | Domain | Cobalamin (vitamin B12)-binding domain | Interproscan |
| IPR037010 | Homologous_superfamily | Vitamin B12-dependent methionine synthase, activation domain superfamily | Interproscan |
| IPR036594 | Homologous_superfamily | Methionine synthase domain | Interproscan |
| IPR003759 | Domain | Cobalamin (vitamin B12)-binding module, cap domain | Interproscan |
| IPR050554 | Family | Methionine Synthase/Corrinoid | Interproscan |
| IPR036589 | Homologous_superfamily | Homocysteine-binding domain superfamily | Interproscan |
| IPR003726 | Domain | Homocysteine-binding domain | Interproscan |
| IPR011005 | Homologous_superfamily | Dihydropteroate synthase-like superfamily | Interproscan |
| IPR011822 | Family | Cobalamin-dependent methionine synthase | Interproscan |
| IPR000489 | Domain | Pterin-binding domain | Interproscan |
| IPR036724 | Homologous_superfamily | Cobalamin-binding domain superfamily | Interproscan |
| IPR033706 | Domain | Methionine synthase, B12-binding domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR011527 | Domain | ABC transporter type 1, transmembrane domain | Interproscan |
| IPR036640 | Homologous_superfamily | ABC transporter type 1, transmembrane domain superfamily | Interproscan |
| IPR044746 | Domain | ABC transporter C family, six-transmembrane helical domain 1 | Interproscan |
| IPR017871 | Conserved_site | ABC transporter-like, conserved site | Interproscan |
| IPR003439 | Domain | ABC transporter-like, ATP-binding domain | Interproscan |
| IPR050173 | Family | ATP-binding cassette transporter C | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11915 | SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN | Interproscan |
| PTHR11686 | GAMMA GLUTAMYL TRANSPEPTIDASE | Interproscan |
| PTHR33332 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR13856 | VHS DOMAIN CONTAINING PROTEIN FAMILY | Interproscan |
| PTHR46670 | ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR47649 | RIBONUCLEASE D | Interproscan |
| PTHR46728 | AN1-TYPE ZINC FINGER PROTEIN 4 | Interproscan |
| PTHR45833 | METHIONINE SYNTHASE | Interproscan |
| PTHR24223 | ATP-BINDING CASSETTE SUB-FAMILY C | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006784 | Biological Process | heme A biosynthetic process | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0016653 | Molecular Function | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0030036 | Biological Process | actin cytoskeleton organization | Interproscan |
| GO:0030054 | Cellular Component | cell junction | Interproscan |
| GO:0030864 | Cellular Component | cortical actin cytoskeleton | Interproscan |
| GO:0042995 | Cellular Component | cell projection | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:0005543 | Molecular Function | phospholipid binding | Interproscan |
| GO:0006751 | Biological Process | glutathione catabolic process | Interproscan |
| GO:0036374 | Molecular Function | glutathione hydrolase activity | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0005768 | Cellular Component | endosome | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0030276 | Molecular Function | clathrin binding | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0044237 | Biological Process | obsolete cellular metabolic process | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0006139 | Biological Process | nucleobase-containing compound metabolic process | Interproscan |
| GO:0008408 | Molecular Function | 3'-5' exonuclease activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0008705 | Molecular Function | methionine synthase activity | Interproscan |
| GO:0009086 | Biological Process | methionine biosynthetic process | Interproscan |
| GO:0031419 | Molecular Function | cobalamin binding | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046653 | Biological Process | tetrahydrofolate metabolic process | Interproscan |
| GO:0050667 | Biological Process | homocysteine metabolic process | Interproscan |
| GO:0042558 | Biological Process | pteridine-containing compound metabolic process | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:0140359 | Molecular Function | ABC-type transporter activity | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0042626 | Molecular Function | ATPase-coupled transmembrane transporter activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K18740 | EXD1, EGL; exonuclease 3'-5' domain-containing protein 1 | - | Cobalamin transport and metabolism | ko04980 | deepkoala |
| Transporters | ko02000 | deepkoala | |||
| CD molecules | ko04090 | deepkoala | |||
| Messenger RNA biogenesis | ko03019 | deepkoala |