Genomic Location: :...
NR annotation: MCH2285442.1, histidinol dehydrogenase [SAR324 cluster bacterium]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q46N53 | Sulfopropanediol 3-dehydrogenase OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) OX=264198 GN=hpsN PE=1 SV=1 | ||||
| Q4FMH0 | Histidinol dehydrogenase homolog OS=Pelagibacter ubique (strain HTCC1062) OX=335992 GN=SAR11_0801 PE=3 SV=1 | ||||
| Q5LVV1 | Sulfopropanediol 3-dehydrogenase OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) OX=246200 GN=hpsN PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | zf-LITAF-like |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00815 | Histidinol_dh | Histidinol dehydrogenase | Family | Interproscan |
| PF10601 | zf-LITAF-like | LITAF-like zinc ribbon domain | Family | Interproscan |
| PF13975 | gag-asp_proteas | gag-polyprotein putative aspartyl protease | Domain | Interproscan |
| PF00081 | Sod_Fe_N | Iron/manganese superoxide dismutases, alpha-hairpin domain | Domain | Interproscan |
| PF13920 | zf-C3HC4_3 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF13181 | TPR_8 | Tetratricopeptide repeat | Repeat | Interproscan |
| PF13424 | TPR_12 | Tetratricopeptide repeat | Repeat | Interproscan |
| PF05669 | Med31 | SOH1 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001692 | Conserved_site | Histidinol dehydrogenase, conserved site | Interproscan |
| IPR012131 | Family | Histidinol dehydrogenase | Interproscan |
| IPR016161 | Homologous_superfamily | Aldehyde/histidinol dehydrogenase | Interproscan |
| IPR006629 | Domain | LPS-induced tumour necrosis factor alpha factor | Interproscan |
| IPR037519 | Family | LITAF domain containing protein | Interproscan |
| IPR021109 | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR001878 | Domain | Zinc finger, CCHC-type | Interproscan |
| IPR001995 | Domain | Peptidase A2A, retrovirus, catalytic | Interproscan |
| IPR035914 | Homologous_superfamily | Spermadhesin, CUB domain superfamily | Interproscan |
| IPR036324 | Homologous_superfamily | Manganese/iron superoxide dismutase, N-terminal domain superfamily | Interproscan |
| IPR001189 | Family | Manganese/iron superoxide dismutase | Interproscan |
| IPR019831 | Domain | Manganese/iron superoxide dismutase, N-terminal | Interproscan |
| IPR051728 | Family | RING-FYVE domain-containing E3 ubiquitin-protein ligase | Interproscan |
| IPR036361 | Homologous_superfamily | SAP domain superfamily | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR011011 | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR011990 | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR019734 | Repeat | Tetratricopeptide repeat | Interproscan |
| IPR024812 | Family | Tetratricopeptide repeat protein 24 | Interproscan |
| IPR037033 | Homologous_superfamily | DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily | Interproscan |
| IPR008831 | Family | Mediator complex, subunit Med31 | Interproscan |
| IPR038089 | Homologous_superfamily | Mediator of RNA polymerase II, subunit Med31 superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21256 | HISTIDINOL DEHYDROGENASE HDH | Interproscan |
| PTHR23292 | LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR | Interproscan |
| PTHR36943 | CCHC-TYPE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR43595 | 37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL | Interproscan |
| PTHR38337 | AGAP010540-PA | Interproscan |
| PTHR14879 | CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING | Interproscan |
| PTHR47050 | TETRATRICOPEPTIDE REPEAT PROTEIN 24 | Interproscan |
| PTHR13186 | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0000105 | Biological Process | L-histidine biosynthetic process | Interproscan |
| GO:0004399 | Molecular Function | histidinol dehydrogenase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0004190 | Molecular Function | aspartic-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0004784 | Molecular Function | superoxide dismutase activity | Interproscan |
| GO:0006801 | Biological Process | superoxide metabolic process | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0070936 | Biological Process | protein K48-linked ubiquitination | Interproscan |
| GO:1902042 | Biological Process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | Interproscan |
| GO:2001271 | Biological Process | obsolete negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0003899 | Molecular Function | DNA-directed 5'-3' RNA polymerase activity | Interproscan |
| GO:0006351 | Biological Process | DNA-templated transcription | Interproscan |
| GO:0003712 | Molecular Function | transcription coregulator activity | Interproscan |
| GO:0006355 | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0016592 | Cellular Component | mediator complex | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0070847 | Cellular Component | core mediator complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20804 | RNF34; E3 ubiquitin-protein ligase RNF34 | EC:2.3.2.31 | Lysosome | ko04142 | deepkoala |
| Ubiquitin system | ko04121 | deepkoala |