Genomic Location: :...
NR annotation: ETE65653.1, Rho guanine nucleotide exchange factor 12, partial [Ophiophagus hannah]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q9NZN5 | Rho guanine nucleotide exchange factor 12 OS=Homo sapiens OX=9606 GN=ARHGEF12 PE=1 SV=1 | ||||
| Q8R4H2 | Rho guanine nucleotide exchange factor 12 OS=Mus musculus OX=10090 GN=Arhgef12 PE=1 SV=2 | ||||
| O15085 | Rho guanine nucleotide exchange factor 11 OS=Homo sapiens OX=9606 GN=ARHGEF11 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | ULD|UFD|RAWUL |
| Ubiquitin Family | ULD|UFD/UBQ|UBQ_PIM |
| Ubiquitin Family | DUB|USP|USP |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16207 | RAWUL | RAWUL domain RING finger- and WD40-associated ubiquitin-like | Domain | Interproscan |
| PF13923 | zf-C3HC4_2 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF05380 | Peptidase_A17 | Pao retrotransposon peptidase | Family | Interproscan |
| PF15711 | ILEI | Interleukin-like EMT inducer | Domain | Interproscan |
| PF00595 | PDZ | PDZ domain | Domain | Interproscan |
| PF19718 | USP47_C | Ubiquitin carboxyl-terminal hydrolase 47 C-terminal | Domain | Interproscan |
| PF00443 | UCH | Ubiquitin carboxyl-terminal hydrolase | Family | Interproscan |
| PF05649 | Peptidase_M13_N | Peptidase family M13 | Family | Interproscan |
| PF01431 | Peptidase_M13 | Peptidase family M13 | Family | Interproscan |
| PF01255 | Prenyltransf | Putative undecaprenyl diphosphate synthase | Family | Interproscan |
| PF14580 | LRR_9 | Leucine-rich repeat | Repeat | Interproscan |
| PF13847 | Methyltransf_31 | Methyltransferase domain | Domain | Interproscan |
| PF01756 | ACOX | Acyl-CoA oxidase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017907 | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR051507 | Family | Polycomb group RING finger | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR032443 | Domain | RAWUL domain | Interproscan |
| IPR008042 | Family | Retrotransposon, Pao | Interproscan |
| IPR001478 | Domain | PDZ domain | Interproscan |
| IPR039477 | Domain | ILEI/PANDER domain | Interproscan |
| IPR036034 | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR028889 | Domain | Ubiquitin specific protease domain | Interproscan |
| IPR018200 | Conserved_site | Ubiquitin specific protease, conserved site | Interproscan |
| IPR045578 | Domain | Ubiquitin carboxyl-terminal hydrolase 47, C-terminal | Interproscan |
| IPR001394 | Domain | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | Interproscan |
| IPR050164 | Family | Ubiquitin carboxyl-terminal hydrolases | Interproscan |
| IPR038765 | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR042089 | Homologous_superfamily | Peptidase M13, domain 2 | Interproscan |
| IPR018497 | Domain | Peptidase M13, C-terminal domain | Interproscan |
| IPR000718 | Family | Peptidase M13 | Interproscan |
| IPR008753 | Domain | Peptidase M13, N-terminal domain | Interproscan |
| IPR001441 | Family | Decaprenyl diphosphate synthase-like | Interproscan |
| IPR036424 | Homologous_superfamily | Decaprenyl diphosphate synthase-like superfamily | Interproscan |
| IPR050836 | Family | SDS22/Internalin LRR-containing | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR029063 | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR051419 | Family | Lysine/N-terminal Methyltransferase Superfamily | Interproscan |
| IPR025714 | Domain | Methyltransferase domain | Interproscan |
| IPR002655 | Domain | Acyl-CoA oxidase, C-terminal | Interproscan |
| IPR036250 | Homologous_superfamily | Acyl-CoA dehydrogenase-like, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45893 | POLYCOMB GROUP RING FINGER PROTEIN | Interproscan |
| PTHR22955 | RETROTRANSPOSON | Interproscan |
| PTHR45872 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D | Interproscan |
| PTHR24006 | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE | Interproscan |
| PTHR11733 | ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED | Interproscan |
| PTHR10291 | DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER | Interproscan |
| PTHR46652 | LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED | Interproscan |
| PTHR12176 | SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0035102 | Cellular Component | PRC1 complex | Interproscan |
| GO:0036353 | Biological Process | obsolete histone H2A-K119 monoubiquitination | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0001664 | Molecular Function | G protein-coupled receptor binding | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0007186 | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| GO:0004843 | Molecular Function | cysteine-type deubiquitinase activity | Interproscan |
| GO:0016579 | Biological Process | protein deubiquitination | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0016485 | Biological Process | protein processing | Interproscan |
| GO:0016765 | Molecular Function | transferase activity, transferring alkyl or aryl (other than methyl) groups | Interproscan |
| GO:0002094 | Molecular Function | polyprenyltransferase activity | Interproscan |
| GO:0005783 | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0016094 | Biological Process | polyprenol biosynthetic process | Interproscan |
| GO:0045547 | Molecular Function | dehydrodolichyl diphosphate synthase activity | Interproscan |
| GO:1904423 | Cellular Component | dehydrodolichyl diphosphate synthase complex | Interproscan |
| GO:0003997 | Molecular Function | acyl-CoA oxidase activity | Interproscan |
| GO:0005777 | Cellular Component | peroxisome | Interproscan |
| GO:0006635 | Biological Process | fatty acid beta-oxidation | Interproscan |
| GO:0016627 | Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K03521 | fixA, etfB; electron transfer flavoprotein beta subunit | - | Cytoskeleton proteins | ko04812 | deepkoala |
| Ubiquitin system | ko04121 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| Energy metabolism | - | deepkoala |