Gene detail

Detailed information of g430.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_022799973.1, insulin receptor substrate 1-like isoform X2 [Stylophora pistillata]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P35570	Insulin receptor substrate 1 OS=Rattus norvegicus OX=10116 GN=Irs1 PE=1 SV=1
P35569	Insulin receptor substrate 1 OS=Mus musculus OX=10090 GN=Irs1 PE=1 SV=1
P35568	Insulin receptor substrate 1 OS=Homo sapiens OX=9606 GN=IRS1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000431 (this species only)
Orthogroup (gene family)	OG0000974 (this species only)
Orthogroup (gene family)	OG0003204 (this species only)
Orthogroup (gene family)	OG0003567 (this species only)
Orthogroup (gene family)	OG0003864 (this species only)
Orthogroup (gene family)	OG0004555 (this species only)
Orthogroup (gene family)	OG0005249 (this species only)
Orthogroup (gene family)	OG0006021 (this species only)
Orthogroup (gene family)	OG0006278 (this species only)
Orthogroup (gene family)	OG0007019 (this species only)
Orthogroup (gene family)	OG0007055 (this species only)
Orthogroup (gene family)	OG0007882 (this species only)
Orthogroup (gene family)	OG0009649 (this species only)
Orthogroup (gene family)	OG0029716 (this species only)
Orthogroup (gene family)	OG0080342 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03813 all species →	Nrap	Nrap protein domain 1	Domain	Interproscan
PF04970 all species →	LRAT	Lecithin retinol acyltransferase	Domain	Interproscan
PF02759 all species →	RUN	RUN domain	Family	Interproscan
PF00169 all species →	PH	PH domain	Domain	Interproscan
PF02174 all species →	IRS	PTB domain (IRS-1 type)	Domain	Interproscan
PF14909 all species →	SPATA6	Spermatogenesis-assoc protein 6	Family	Interproscan
PF13650 all species →	Asp_protease_2	Aspartyl protease	Domain	Interproscan
PF01585 all species →	G-patch	G-patch domain	Family	Interproscan
PF07713 all species →	DUF1604	Protein of unknown function (DUF1604)	Family	Interproscan
PF00071 all species →	Ras	Ras family	Domain	Interproscan
PF00621 all species →	RhoGEF	RhoGEF domain	Domain	Interproscan
PF07653 all species →	SH3_2	Variant SH3 domain	Domain	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan
PF00225 all species →	Kinesin	Kinesin motor domain	Domain	Interproscan
PF15717 all species →	PCM1_C	Pericentriolar material 1 C terminus	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR035082 all species →	Domain	Nrap protein domain 1	Interproscan
IPR005554 all species →	Family	NOL6/Upt22	Interproscan
IPR042086 all species →	Homologous_superfamily	Methyltransferase, alpha-helical capping domain	Interproscan
IPR029063 all species →	Homologous_superfamily	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Interproscan
IPR007053 all species →	Domain	LRAT domain	Interproscan
IPR004012 all species →	Domain	RUN domain	Interproscan
IPR037213 all species →	Homologous_superfamily	RUN domain superfamily	Interproscan
IPR039011 all species →	Family	Insulin receptor substrate	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR002404 all species →	Domain	IRS-type PTB domain	Interproscan
IPR032732 all species →	Domain	Spermatogenesis-associated protein 6, N-terminal	Interproscan
IPR042769 all species →	Family	SPATA6 family	Interproscan
IPR052865 all species →	Family	Zinc finger BED domain-containing protein	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR021109 all species →	Homologous_superfamily	Aspartic peptidase domain superfamily	Interproscan
IPR000467 all species →	Domain	G-patch domain	Interproscan
IPR011666 all species →	Domain	G patch domain-containing protein, N-terminal	Interproscan
IPR001806 all species →	Family	Small GTPase	Interproscan
IPR005225 all species →	Domain	Small GTP-binding protein domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR000219 all species →	Domain	Dbl homology (DH) domain	Interproscan
IPR035899 all species →	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR001331 all species →	Conserved_site	Guanine-nucleotide dissociation stimulator, CDC24, conserved site	Interproscan
IPR053086 all species →	Family	RhoGEF domain-containing protein	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan
IPR036961 all species →	Homologous_superfamily	Kinesin motor domain superfamily	Interproscan
IPR027640 all species →	Family	Kinesin-like protein	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR001752 all species →	Domain	Kinesin motor domain	Interproscan
IPR019821 all species →	Conserved_site	Kinesin motor domain, conserved site	Interproscan
IPR031446 all species →	Domain	Pericentriolar material 1 protein, C-terminal	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR002110 all species →	Repeat	Ankyrin repeat	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR17972 all species →	NUCLEOLAR RNA-ASSOCIATED PROTEIN	Interproscan
PTHR47194 all species →	SORTING NEXIN-29-RELATED	Interproscan
PTHR10614 all species →	INSULIN RECEPTOR SUBSTRATE	Interproscan
PTHR16435 all species →	SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6	Interproscan
PTHR47241 all species →	FINGER PROTEIN, PUTATIVE-RELATED	Interproscan
PTHR13384 all species →	G PATCH DOMAIN-CONTAINING PROTEIN 1	Interproscan
PTHR24073 all species →	DRAB5-RELATED	Interproscan
PTHR45834 all species →	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED	Interproscan
PTHR24115 all species →	KINESIN-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006364 all species →	Biological Process	rRNA processing	Interproscan
GO:0006409 all species →	Biological Process	tRNA export from nucleus	Interproscan
GO:0032040 all species →	Cellular Component	small-subunit processome	Interproscan
GO:0032545 all species →	Cellular Component	CURI complex	Interproscan
GO:0034456 all species →	Cellular Component	UTP-C complex	Interproscan
GO:0005158 all species →	Molecular Function	insulin receptor binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0008286 all species →	Biological Process	insulin receptor signaling pathway	Interproscan
GO:0043548 all species →	Molecular Function	phosphatidylinositol 3-kinase binding	Interproscan
GO:0007283 all species →	Biological Process	spermatogenesis	Interproscan
GO:0032027 all species →	Molecular Function	myosin light chain binding	Interproscan
GO:0097224 all species →	Cellular Component	obsolete sperm connecting piece	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0003723 all species →	Molecular Function	RNA binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006397 all species →	Biological Process	mRNA processing	Interproscan
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0006886 all species →	Biological Process	intracellular protein transport	Interproscan
GO:0012505 all species →	Cellular Component	endomembrane system	Interproscan
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0003777 all species →	Molecular Function	microtubule motor activity	Interproscan
GO:0005871 all species →	Cellular Component	kinesin complex	Interproscan
GO:0005874 all species →	Cellular Component	microtubule	Interproscan
GO:0007018 all species →	Biological Process	microtubule-based movement	Interproscan
GO:0008017 all species →	Molecular Function	microtubule binding	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05769	ARHGEF4_29, ASEF1_2; Rho guanine nucleotide exchange factor 4/29	-	Membrane trafficking	ko04131	deepkoala
K07911	RAB20; Ras-related protein Rab-20	-	GTP-binding proteins	ko04031	deepkoala
K13123	GPATCH1; G patch domain-containing protein 1	-	Spliceosome	ko03041	deepkoala
K16172	IRS1; insulin receptor substrate 1	-	Insulin resistance	ko04931	deepkoala
K23224	SPATA6; spermatogenesis-associated protein 6	-	Cilium and associated proteins	ko03037	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.