Genomic Location: :...
NR annotation: XP_022799973.1, insulin receptor substrate 1-like isoform X2 [Stylophora pistillata]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| P35570 | Insulin receptor substrate 1 OS=Rattus norvegicus OX=10116 GN=Irs1 PE=1 SV=1 |
| P35569 | Insulin receptor substrate 1 OS=Mus musculus OX=10090 GN=Irs1 PE=1 SV=1 |
| P35568 | Insulin receptor substrate 1 OS=Homo sapiens OX=9606 GN=IRS1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03813 | Nrap | Nrap protein domain 1 | Domain | Interproscan |
| PF04970 | LRAT | Lecithin retinol acyltransferase | Domain | Interproscan |
| PF02759 | RUN | RUN domain | Family | Interproscan |
| PF00169 | PH | PH domain | Domain | Interproscan |
| PF02174 | IRS | PTB domain (IRS-1 type) | Domain | Interproscan |
| PF14909 | SPATA6 | Spermatogenesis-assoc protein 6 | Family | Interproscan |
| PF13650 | Asp_protease_2 | Aspartyl protease | Domain | Interproscan |
| PF01585 | G-patch | G-patch domain | Family | Interproscan |
| PF07713 | DUF1604 | Protein of unknown function (DUF1604) | Family | Interproscan |
| PF00071 | Ras | Ras family | Domain | Interproscan |
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF07653 | SH3_2 | Variant SH3 domain | Domain | Interproscan |
| PF07714 | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| PF00225 | Kinesin | Kinesin motor domain | Domain | Interproscan |
| PF15717 | PCM1_C | Pericentriolar material 1 C terminus | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR035082 | Domain | Nrap protein domain 1 | Interproscan |
| IPR005554 | Family | NOL6/Upt22 | Interproscan |
| IPR042086 | Homologous_superfamily | Methyltransferase, alpha-helical capping domain | Interproscan |
| IPR029063 | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR007053 | Domain | LRAT domain | Interproscan |
| IPR004012 | Domain | RUN domain | Interproscan |
| IPR037213 | Homologous_superfamily | RUN domain superfamily | Interproscan |
| IPR039011 | Family | Insulin receptor substrate | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR002404 | Domain | IRS-type PTB domain | Interproscan |
| IPR032732 | Domain | Spermatogenesis-associated protein 6, N-terminal | Interproscan |
| IPR042769 | Family | SPATA6 family | Interproscan |
| IPR052865 | Family | Zinc finger BED domain-containing protein | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR021109 | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR000467 | Domain | G-patch domain | Interproscan |
| IPR011666 | Domain | G patch domain-containing protein, N-terminal | Interproscan |
| IPR001806 | Family | Small GTPase | Interproscan |
| IPR005225 | Domain | Small GTP-binding protein domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR001331 | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| IPR053086 | Family | RhoGEF domain-containing protein | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR036961 | Homologous_superfamily | Kinesin motor domain superfamily | Interproscan |
| IPR027640 | Family | Kinesin-like protein | Interproscan |
| IPR001245 | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR001752 | Domain | Kinesin motor domain | Interproscan |
| IPR019821 | Conserved_site | Kinesin motor domain, conserved site | Interproscan |
| IPR031446 | Domain | Pericentriolar material 1 protein, C-terminal | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR17972 | NUCLEOLAR RNA-ASSOCIATED PROTEIN | Interproscan |
| PTHR47194 | SORTING NEXIN-29-RELATED | Interproscan |
| PTHR10614 | INSULIN RECEPTOR SUBSTRATE | Interproscan |
| PTHR16435 | SPERMATOGENESIS-ASSOCIATED PROTEIN 6 SPATA6 | Interproscan |
| PTHR47241 | FINGER PROTEIN, PUTATIVE-RELATED | Interproscan |
| PTHR13384 | G PATCH DOMAIN-CONTAINING PROTEIN 1 | Interproscan |
| PTHR24073 | DRAB5-RELATED | Interproscan |
| PTHR45834 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED | Interproscan |
| PTHR24115 | KINESIN-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006364 | Biological Process | rRNA processing | Interproscan |
| GO:0006409 | Biological Process | tRNA export from nucleus | Interproscan |
| GO:0032040 | Cellular Component | small-subunit processome | Interproscan |
| GO:0032545 | Cellular Component | CURI complex | Interproscan |
| GO:0034456 | Cellular Component | UTP-C complex | Interproscan |
| GO:0005158 | Molecular Function | insulin receptor binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0008286 | Biological Process | insulin receptor signaling pathway | Interproscan |
| GO:0043548 | Molecular Function | phosphatidylinositol 3-kinase binding | Interproscan |
| GO:0007283 | Biological Process | spermatogenesis | Interproscan |
| GO:0032027 | Molecular Function | myosin light chain binding | Interproscan |
| GO:0097224 | Cellular Component | obsolete sperm connecting piece | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006397 | Biological Process | mRNA processing | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0006886 | Biological Process | intracellular protein transport | Interproscan |
| GO:0012505 | Cellular Component | endomembrane system | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0003777 | Molecular Function | microtubule motor activity | Interproscan |
| GO:0005871 | Cellular Component | kinesin complex | Interproscan |
| GO:0005874 | Cellular Component | microtubule | Interproscan |
| GO:0007018 | Biological Process | microtubule-based movement | Interproscan |
| GO:0008017 | Molecular Function | microtubule binding | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07911 | RAB20; Ras-related protein Rab-20 | - | Insulin resistance | ko04931 | deepkoala |
| Membrane trafficking | ko04131 | deepkoala | |||
| Cilium and associated proteins | ko03037 | deepkoala | |||
| Spliceosome | ko03041 | deepkoala | |||
| GTP-binding proteins | ko04031 | deepkoala |