Genomic Location: :...
NR annotation: XP_002154561.4, nibrin [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q5I2W8 | Nibrin OS=Danio rerio OX=7955 GN=nbn PE=2 SV=2 |
| G5EFS2 | RNA-binding protein Musashi homolog 1 OS=Caenorhabditis elegans OX=6239 GN=msi-1 PE=1 SV=1 |
| O43347 | RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00378 | ECH_1 | Enoyl-CoA hydratase/isomerase | Domain | Interproscan |
| PF18072 | FGAR-AT_linker | Formylglycinamide ribonucleotide amidotransferase linker domain | Domain | Interproscan |
| PF18076 | FGAR-AT_N | Formylglycinamide ribonucleotide amidotransferase N-terminal | Domain | Interproscan |
| PF14716 | HHH_8 | Helix-hairpin-helix domain | Domain | Interproscan |
| PF14792 | DNA_pol_B_palm | DNA polymerase beta palm | Domain | Interproscan |
| PF14791 | DNA_pol_B_thumb | DNA polymerase beta thumb | Family | Interproscan |
| PF10391 | DNA_pol_lambd_f | Fingers domain of DNA polymerase lambda | Domain | Interproscan |
| PF16508 | NIBRIN_BRCT_II | Second BRCT domain on Nijmegen syndrome breakage protein | Domain | Interproscan |
| PF00665 | rve | Integrase core domain | Domain | Interproscan |
| PF00076 | RRM_1 | RNA recognition motif | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001753 | Family | Enoyl-CoA hydratase/isomerase | Interproscan |
| IPR018376 | Conserved_site | Enoyl-CoA hydratase/isomerase, conserved site | Interproscan |
| IPR029045 | Homologous_superfamily | ClpP/crotonase-like domain superfamily | Interproscan |
| IPR041609 | Domain | Phosphoribosylformylglycinamidine synthase, linker domain | Interproscan |
| IPR036604 | Homologous_superfamily | Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily | Interproscan |
| IPR036921 | Homologous_superfamily | PurM-like, N-terminal domain superfamily | Interproscan |
| IPR040707 | Domain | Phosphoribosylformylglycinamidine synthase, N-terminal | Interproscan |
| IPR022312 | Family | DNA polymerase family X | Interproscan |
| IPR019843 | Binding_site | DNA polymerase family X, binding site | Interproscan |
| IPR010996 | Domain | DNA polymerase beta-like, N-terminal domain | Interproscan |
| IPR028207 | Domain | DNA polymerase beta, palm domain | Interproscan |
| IPR029398 | Domain | DNA polymerase beta, thumb domain | Interproscan |
| IPR002054 | Domain | DNA-directed DNA polymerase X | Interproscan |
| IPR043519 | Homologous_superfamily | Nucleotidyltransferase superfamily | Interproscan |
| IPR002008 | Family | DNA polymerase family X, beta-like | Interproscan |
| IPR027421 | Homologous_superfamily | DNA polymerase lambda lyase domain superfamily | Interproscan |
| IPR018944 | Domain | DNA polymerase lambda, fingers domain | Interproscan |
| IPR037160 | Homologous_superfamily | DNA polymerase, thumb domain superfamily | Interproscan |
| IPR043014 | Homologous_superfamily | Nibrin, second BRCT domain superfamily | Interproscan |
| IPR036420 | Homologous_superfamily | BRCT domain superfamily | Interproscan |
| IPR013908 | Domain | Nibrin, C-terminal | Interproscan |
| IPR032429 | Domain | Nibrin, second BRCT domain | Interproscan |
| IPR040227 | Family | Nibrin-related | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR027469 | Homologous_superfamily | Cation efflux transmembrane domain superfamily | Interproscan |
| IPR026765 | Family | Transmembrane protein 163 | Interproscan |
| IPR012677 | Homologous_superfamily | Nucleotide-binding alpha-beta plait domain superfamily | Interproscan |
| IPR000504 | Domain | RNA recognition motif domain | Interproscan |
| IPR035979 | Homologous_superfamily | RNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11941 | ENOYL-COA HYDRATASE-RELATED | Interproscan |
| PTHR10099 | PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE | Interproscan |
| PTHR11276 | DNA POLYMERASE TYPE-X FAMILY MEMBER | Interproscan |
| PTHR12162 | NIBRIN-RELATED | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR31937 | TRANSMEMBRANE PROTEIN 163 | Interproscan |
| PTHR48032 | RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0004300 | Molecular Function | enoyl-CoA hydratase activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006635 | Biological Process | fatty acid beta-oxidation | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0003887 | Molecular Function | DNA-directed DNA polymerase activity | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0016779 | Molecular Function | nucleotidyltransferase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006303 | Biological Process | double-strand break repair via nonhomologous end joining | Interproscan |
| GO:0034061 | Molecular Function | DNA polymerase activity | Interproscan |
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0003684 | Molecular Function | damaged DNA binding | Interproscan |
| GO:0006302 | Biological Process | double-strand break repair | Interproscan |
| GO:0007095 | Biological Process | mitotic G2 DNA damage checkpoint signaling | Interproscan |
| GO:0030870 | Cellular Component | Mre11 complex | Interproscan |
| GO:0032508 | Biological Process | DNA duplex unwinding | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0003729 | Molecular Function | mRNA binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005844 | Cellular Component | obsolete polysome | Interproscan |
| GO:0006417 | Biological Process | regulation of translation | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K14694 | SLC30A11, ZNT11; solute carrier family 30 (zinc transporter), member 11 | - | DNA repair and recombination proteins | ko03400 | deepkoala |
| Transporters | ko02000 | deepkoala |