Genomic Location: :...
NR annotation: EDO37155.1, predicted protein, partial [Nematostella vectensis]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q15084 | Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 | ||||
| Q922R8 | Protein disulfide-isomerase A6 OS=Mus musculus OX=10090 GN=Pdia6 PE=1 SV=3 | ||||
| Q5R6T1 | Protein disulfide-isomerase A6 OS=Pongo abelii OX=9601 GN=PDIA6 PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|CDC20 |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00171 | Aldedh | Aldehyde dehydrogenase family | Family | Interproscan |
| PF00085 | Thioredoxin | Thioredoxin | Domain | Interproscan |
| PF00071 | Ras | Ras family | Domain | Interproscan |
| PF13843 | DDE_Tnp_1_7 | Transposase IS4 | Domain | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| PF13927 | Ig_3 | Immunoglobulin domain | Domain | Interproscan |
| PF07679 | I-set | Immunoglobulin I-set domain | Domain | Interproscan |
| PF00530 | SRCR | Scavenger receptor cysteine-rich domain | Domain | Interproscan |
| PF06534 | RGM_C | Repulsive guidance molecule (RGM) C-terminus | Family | Interproscan |
| PF06535 | RGM_N | Repulsive guidance molecule (RGM) N-terminus | Family | Interproscan |
| PF00883 | Peptidase_M17 | Cytosol aminopeptidase family, catalytic domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016161 | Homologous_superfamily | Aldehyde/histidinol dehydrogenase | Interproscan |
| IPR016160 | Conserved_site | Aldehyde dehydrogenase, cysteine active site | Interproscan |
| IPR016162 | Homologous_superfamily | Aldehyde dehydrogenase, N-terminal | Interproscan |
| IPR029510 | Conserved_site | Aldehyde dehydrogenase, glutamic acid active site | Interproscan |
| IPR015590 | Domain | Aldehyde dehydrogenase domain | Interproscan |
| IPR016163 | Homologous_superfamily | Aldehyde dehydrogenase, C-terminal | Interproscan |
| IPR013766 | Domain | Thioredoxin domain | Interproscan |
| IPR017937 | Conserved_site | Thioredoxin, conserved site | Interproscan |
| IPR036249 | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR005788 | Domain | Protein disulfide-isomerase, thioredoxin-like domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR001806 | Family | Small GTPase | Interproscan |
| IPR020849 | Family | Small GTPase, Ras-type | Interproscan |
| IPR005225 | Domain | Small GTP-binding protein domain | Interproscan |
| IPR029526 | Domain | PiggyBac transposable element-derived protein | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR044633 | Family | Cleavage stimulation factor subunit 1-like | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR013783 | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR006212 | Repeat | Furin-like repeat | Interproscan |
| IPR001190 | Domain | SRCR domain | Interproscan |
| IPR009030 | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR036179 | Homologous_superfamily | Immunoglobulin-like domain superfamily | Interproscan |
| IPR007110 | Domain | Immunoglobulin-like domain | Interproscan |
| IPR003599 | Domain | Immunoglobulin subtype | Interproscan |
| IPR036772 | Homologous_superfamily | SRCR-like domain superfamily | Interproscan |
| IPR017448 | Domain | SRCR-like domain | Interproscan |
| IPR000742 | Domain | EGF-like domain | Interproscan |
| IPR003598 | Domain | Immunoglobulin subtype 2 | Interproscan |
| IPR013098 | Domain | Immunoglobulin I-set | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR039863 | Family | Dickkopf related protein 1-4 | Interproscan |
| IPR009496 | Domain | Repulsive guidance molecule, C-terminal | Interproscan |
| IPR010536 | Domain | Repulsive guidance molecule, N-terminal | Interproscan |
| IPR040287 | Family | Repulsive guidance molecule | Interproscan |
| IPR011356 | Family | Peptidase M17, leucine aminopeptidase/peptidase B | Interproscan |
| IPR000819 | Domain | Peptidase M17, leucyl aminopeptidase, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | Interproscan |
| PTHR45815 | PROTEIN DISULFIDE-ISOMERASE A6 | Interproscan |
| PTHR24070 | RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY | Interproscan |
| PTHR46599 | PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 | Interproscan |
| PTHR44133 | CLEAVAGE STIMULATION FACTOR SUBUNIT 1 | Interproscan |
| PTHR10075 | BASIGIN RELATED | Interproscan |
| PTHR12113 | DICKKOPF3-LIKE 3 | Interproscan |
| PTHR31428 | RGM DOMAIN FAMILY MEMBER DRAG-1 | Interproscan |
| PTHR11963 | LEUCINE AMINOPEPTIDASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004029 | Molecular Function | aldehyde dehydrogenase (NAD+) activity | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0016620 | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0005788 | Cellular Component | endoplasmic reticulum lumen | Interproscan |
| GO:0015035 | Molecular Function | protein-disulfide reductase activity | Interproscan |
| GO:0034976 | Biological Process | response to endoplasmic reticulum stress | Interproscan |
| GO:0003756 | Molecular Function | protein disulfide isomerase activity | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0019003 | Molecular Function | GDP binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005848 | Cellular Component | mRNA cleavage stimulating factor complex | Interproscan |
| GO:0031124 | Biological Process | mRNA 3'-end processing | Interproscan |
| GO:0007156 | Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules | Interproscan |
| GO:0007411 | Biological Process | axon guidance | Interproscan |
| GO:0030424 | Cellular Component | axon | Interproscan |
| GO:0070593 | Biological Process | dendrite self-avoidance | Interproscan |
| GO:0098632 | Molecular Function | cell-cell adhesion mediator activity | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0039706 | Molecular Function | co-receptor binding | Interproscan |
| GO:0048019 | Molecular Function | receptor antagonist activity | Interproscan |
| GO:0090090 | Biological Process | negative regulation of canonical Wnt signaling pathway | Interproscan |
| GO:0015026 | Molecular Function | coreceptor activity | Interproscan |
| GO:0030509 | Biological Process | BMP signaling pathway | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0019538 | Biological Process | protein metabolic process | Interproscan |
| GO:0030145 | Molecular Function | manganese ion binding | Interproscan |
| GO:0070006 | Molecular Function | metalloaminopeptidase activity | Interproscan |
| GO:0004177 | Molecular Function | aminopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0008233 | Molecular Function | peptidase activity | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01255 | CARP, pepA; leucyl aminopeptidase | EC:3.4.11.1 | Membrane trafficking | ko04131 | deepkoala |
| Alcoholic liver disease | ko04936 | deepkoala | |||
| Axon guidance | ko04360 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| GTP-binding proteins | ko04031 | deepkoala | |||
| Peptidases and inhibitors | ko01002 | deepkoala |