Genomic Location: Sc0000000:19114...29182
NR annotation: CAH3145190.1, unnamed protein product [Porites lobata]
Species Montipora capitata · all data for this species · gene families
| CDS |
| g5.t1 |
| Transcript |
| g5.t1 |
| Protein |
| g5.t1 |
| UniProt accession | Description |
|---|---|
| Q07E01 | Hepatocyte growth factor receptor OS=Ornithorhynchus anatinus OX=9258 GN=MET PE=3 SV=1 |
| P16056 | Hepatocyte growth factor receptor OS=Mus musculus OX=10090 GN=Met PE=1 SV=1 |
| Q8QFP9 | Tyrosine-protein kinase receptor TYRO3 OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007892 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02019 all species → | WIF | WIF domain | Family | Interproscan |
| PF07714 all species → | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003306 all species → | Domain | WIF domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR050122 all species → | Family | Receptor Tyrosine Kinase | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR001245 all species → | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR038677 all species → | Homologous_superfamily | WIF domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24416 all species → | TYROSINE-PROTEIN KINASE RECEPTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004714 all species → | Molecular Function | transmembrane receptor protein tyrosine kinase activity | Interproscan |
| GO:0005887 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007169 all species → | Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | Interproscan |
| GO:0007275 all species → | Biological Process | multicellular organism development | Interproscan |
| GO:0033674 all species → | Biological Process | positive regulation of kinase activity | Interproscan |
| GO:0043235 all species → | Cellular Component | receptor complex | Interproscan |
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
g5.t1.Transcript abundance of g5.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organisms · ambient pH treatment | 21 | 21 | 61.23 | 179.84 | |
| whole organisms · low pH treatment | 15 | 15 | 60.13 | 183.10 | |
| whole organisms · extra low pH treatment pH treatment | 12 | 12 | 67.57 | 206.80 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR11452242 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 179.84 |
| SRR11452243 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 103.47 |
| SRR11452222 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 89.83 |
| SRR11452237 | whole organisms · ambient pH treatment | whole organisms | gastrula | ambient pH treatment | SRP254626 | 85.06 |
| SRR11452230 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 82.63 |
| SRR11452250 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 73.87 |
| SRR11452228 | whole organisms · ambient pH treatment | whole organisms | planulae | ambient pH treatment | SRP254626 | 72.57 |
| SRR11452232 | whole organisms · ambient pH treatment | whole organisms | blastula | ambient pH treatment | SRP254626 | 69.97 |
| SRR11452263 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 66.69 |
| SRR11452234 | whole organisms · ambient pH treatment | whole organisms | morula | ambient pH treatment | SRP254626 | 65.33 |
| SRR11452233 | whole organisms · ambient pH treatment | whole organisms | morula | ambient pH treatment | SRP254626 | 52.69 |
| SRR11452246 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 52.31 |
| SRR11452259 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 46.93 |
| SRR11452251 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 43.54 |
| SRR11452252 | whole organisms · ambient pH treatment | whole organisms | prawn chip | ambient pH treatment | SRP254626 | 43.17 |
| SRR11452254 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 33.58 |
| SRR11452260 | whole organisms · ambient pH treatment | whole organisms | cleavage | ambient pH treatment | SRP254626 | 32.38 |
| SRR11452262 | whole organisms · ambient pH treatment | whole organisms | egg | ambient pH treatment | SRP254626 | 28.22 |
| SRR11452217 | whole organisms · ambient pH treatment | whole organisms | fertilized embryo | ambient pH treatment | SRP254626 | 27.36 |
| SRR11452240 | whole organisms · ambient pH treatment | whole organisms | fertilized embryo | ambient pH treatment | SRP254626 | 19.96 |
| SRR11452231 | whole organisms · ambient pH treatment | whole organisms | blastula | ambient pH treatment | SRP254626 | 16.40 |
| SRR11452241 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 183.10 |
| SRR11452238 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 113.97 |
| SRR11452236 | whole organisms · low pH treatment | whole organisms | gastrula | low pH treatment | SRP254626 | 104.75 |
| SRR11452247 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 55.20 |
| SRR11452249 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 53.24 |
| SRR11452223 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 52.31 |
| SRR11452221 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 47.00 |
| SRR11452224 | whole organisms · low pH treatment | whole organisms | planulae | low pH treatment | SRP254626 | 43.61 |
| SRR11452245 | whole organisms · low pH treatment | whole organisms | prawn chip | low pH treatment | SRP254626 | 39.75 |
| SRR11452253 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 37.72 |
| SRR11452218 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 36.62 |
| SRR11452255 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 34.77 |
| SRR11452216 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 34.57 |
| SRR11452229 | whole organisms · low pH treatment | whole organisms | fertilized embryo | low pH treatment | SRP254626 | 34.24 |
| SRR11452258 | whole organisms · low pH treatment | whole organisms | cleavage | low pH treatment | SRP254626 | 31.13 |
| SRR11452239 | whole organisms · extra low pH treatment pH treatment | whole organisms | gastrula | extra low pH treatment pH treatment | SRP254626 | 206.80 |
| SRR11452235 | whole organisms · extra low pH treatment pH treatment | whole organisms | gastrula | extra low pH treatment pH treatment | SRP254626 | 101.48 |
| SRR11452227 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 88.32 |
| SRR11452225 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 79.19 |
| SRR11452226 | whole organisms · extra low pH treatment pH treatment | whole organisms | planulae | extra low pH treatment pH treatment | SRP254626 | 56.46 |
| SRR11452244 | whole organisms · extra low pH treatment pH treatment | whole organisms | prawn chip | extra low pH treatment pH treatment | SRP254626 | 55.58 |
| SRR11452248 | whole organisms · extra low pH treatment pH treatment | whole organisms | prawn chip | extra low pH treatment pH treatment | SRP254626 | 52.91 |
| SRR11452257 | whole organisms · extra low pH treatment pH treatment | whole organisms | cleavage | extra low pH treatment pH treatment | SRP254626 | 47.29 |
| SRR11452219 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 40.31 |
| SRR11452256 | whole organisms · extra low pH treatment pH treatment | whole organisms | cleavage | extra low pH treatment pH treatment | SRP254626 | 31.22 |
| SRR11452261 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 27.30 |
| SRR11452220 | whole organisms · extra low pH treatment pH treatment | whole organisms | fertilized embryo | extra low pH treatment pH treatment | SRP254626 | 24.03 |
Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 18 | g6682.t1 | 0.965371053356039 |
| Negatively correlated | 3 | g11563.t1 | -0.753695634913075 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |