Genomic Location: chr2Alt:36130389...36143923
NR annotation: XP_015759296.1, PREDICTED: elongation factor 2-like [Acropora digitifera]
Species Acropora digitifera · all data for this species · gene families
| CDS |
| g5010.t1 |
| Transcript |
| chr2Alt.g5010.t1 |
| Protein |
| chr2Alt.g5010.t1 |
| UniProt accession | Description |
|---|---|
| Q6P3J5 | Elongation factor 2b OS=Danio rerio OX=7955 GN=eef2b PE=1 SV=1 |
| Q90705 | Elongation factor 2 OS=Gallus gallus OX=9031 GN=EEF2 PE=1 SV=3 |
| Q3SYU2 | Elongation factor 2 OS=Bos taurus OX=9913 GN=EEF2 PE=2 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14492 all species → | EFG_III | Elongation Factor G, domain III | Domain | Interproscan |
| PF00009 all species → | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| PF03764 all species → | EFG_IV | Elongation factor G, domain IV | Domain | Interproscan |
| PF03144 all species → | GTP_EFTU_D2 | Elongation factor Tu domain 2 | Domain | Interproscan |
| PF00679 all species → | EFG_C | Elongation factor G C-terminus | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR041095 all species → | Domain | Elongation Factor G, domain II | Interproscan |
| IPR009000 all species → | Homologous_superfamily | Translation protein, beta-barrel domain superfamily | Interproscan |
| IPR000640 all species → | Domain | Elongation factor EFG, domain V-like | Interproscan |
| IPR014721 all species → | Homologous_superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Interproscan |
| IPR000795 all species → | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR005225 all species → | Domain | Small GTP-binding protein domain | Interproscan |
| IPR005517 all species → | Domain | Translation elongation factor EFG/EF2, domain IV | Interproscan |
| IPR035647 all species → | Homologous_superfamily | EF-G domain III/V-like | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR004161 all species → | Domain | Translation elongation factor EFTu-like, domain 2 | Interproscan |
| IPR031157 all species → | Conserved_site | Tr-type G domain, conserved site | Interproscan |
| IPR020568 all species → | Homologous_superfamily | Ribosomal protein uS5 domain 2-type superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42908 all species → | TRANSLATION ELONGATION FACTOR-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003924 all species → | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 all species → | Molecular Function | GTP binding | Interproscan |
| GO:0003746 all species → | Molecular Function | translation elongation factor activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006414 all species → | Biological Process | translational elongation | Interproscan |
| GO:0043022 all species → | Molecular Function | ribosome binding | Interproscan |
| GO:1990904 all species → | Cellular Component | ribonucleoprotein complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03234 | EEF2; elongation factor 2 | - | Exosome | ko04147 | deepkoala |
Transcript abundance of g5010.t1 across 39 RNA-seq samples of Acropora digitifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Coral branch | 39 | 39 | 742.58 | 1,084.56 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR23047234 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 1,084.56 |
| SRR23047230 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 987.73 |
| SRR23047217 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 971.18 |
| SRR23047227 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 970.11 |
| SRR23047212 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 947.99 |
| SRR23047214 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 936.00 |
| SRR23047206 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 932.51 |
| SRR23047241 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 884.76 |
| SRR23047224 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 868.40 |
| SRR23047213 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 860.81 |
| SRR23047231 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 836.77 |
| SRR23047229 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 821.08 |
| SRR23047240 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 820.88 |
| SRR23047228 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 817.97 |
| SRR23047226 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 813.90 |
| SRR23047216 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 810.40 |
| SRR23047223 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 804.52 |
| SRR23047211 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 797.00 |
| SRR23047237 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 796.80 |
| SRR23047239 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 788.97 |
| SRR23047233 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 783.25 |
| SRR23047215 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 768.71 |
| SRR23047209 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 760.26 |
| SRR23047238 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 740.36 |
| SRR23047225 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 718.76 |
| SRR23047242 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 699.66 |
| SRR23047218 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 698.52 |
| SRR23047235 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 694.06 |
| SRR23047219 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 625.22 |
| SRR23047232 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 611.05 |
| SRR23047236 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 603.13 |
| SRR23047207 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 523.91 |
| SRR23047244 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 520.46 |
| SRR23047220 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 510.59 |
| SRR23047243 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 454.58 |
| SRR23047210 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 442.52 |
| SRR23047208 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 429.82 |
| SRR23047222 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 412.54 |
| SRR23047221 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 410.83 |
Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM,
StringTie quantification over 39 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora digitifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 46 | g2351.t1 | 0.88003071434976 |
| Negatively correlated | 105 | g7924.t1 | -0.897466227617549 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora digitifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 1 available assay. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: DNase-seq (DHS).
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |