Genomic Location: chr2Alt:36366254...36412004
NR annotation: XP_044164313.1, pregnancy zone protein-like [Acropora millepora]
Species Acropora digitifera · all data for this species · gene families
| CDS |
| g5022.t2 |
| Transcript |
| chr2Alt.g5022.t2 |
| Protein |
| chr2Alt.g5022.t2 |
| UniProt accession | Description |
|---|---|
| Q63041 | Alpha-1-macroglobulin OS=Rattus norvegicus OX=10116 GN=A1m PE=1 SV=1 |
| P20742 | Pregnancy zone protein OS=Homo sapiens OX=9606 GN=PZP PE=1 SV=4 |
| Q61838 | Pregnancy zone protein OS=Mus musculus OX=10090 GN=Pzp PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07678 all species → | TED_complement | A-macroglobulin TED domain | Repeat | Interproscan |
| PF17789 all species → | MG4 | Macroglobulin domain MG4 | Domain | Interproscan |
| PF17791 all species → | MG3 | Macroglobulin domain MG3 | Domain | Interproscan |
| PF07703 all species → | A2M_BRD | Alpha-2-macroglobulin bait region domain | Domain | Interproscan |
| PF07677 all species → | A2M_recep | A-macroglobulin receptor binding domain | Domain | Interproscan |
| PF01835 all species → | MG2 | MG2 domain | Domain | Interproscan |
| PF00207 all species → | A2M | Alpha-2-macroglobulin family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011626 all species → | Domain | Alpha-macroglobulin-like, TED domain | Interproscan |
| IPR009048 all species → | Domain | Alpha-macroglobulin, receptor-binding | Interproscan |
| IPR047565 all species → | Conserved_site | Alpha-macroglobulin-like, thiol-ester bond-forming region | Interproscan |
| IPR014756 all species → | Homologous_superfamily | Immunoglobulin E-set | Interproscan |
| IPR036595 all species → | Homologous_superfamily | Alpha-macroglobulin, receptor-binding domain superfamily | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR050473 all species → | Family | Alpha-2-macroglobulin/Complement system | Interproscan |
| IPR040839 all species → | Domain | Macroglobulin domain MG4 | Interproscan |
| IPR041555 all species → | Domain | Macroglobulin domain MG3 | Interproscan |
| IPR011625 all species → | Domain | Alpha-2-macroglobulin, bait region domain | Interproscan |
| IPR001599 all species → | Domain | Alpha-2-macroglobulin | Interproscan |
| IPR008930 all species → | Homologous_superfamily | Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid | Interproscan |
| IPR002890 all species → | Domain | Macroglobulin domain | Interproscan |
| IPR041813 all species → | Domain | Alpha-2-macroglobulin, TED domain | Interproscan |
| IPR019742 all species → | Conserved_site | Alpha-2-macroglobulin, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11412 all species → | MACROGLOBULIN / COMPLEMENT | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005615 all species → | Cellular Component | extracellular space | Interproscan |
| GO:0005576 all species → | Cellular Component | extracellular region | Interproscan |
| GO:0004866 all species → | Molecular Function | endopeptidase inhibitor activity | Interproscan |
g5022.t2.Transcript abundance of g5022.t2 across 39 RNA-seq samples of Acropora digitifera. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Coral branch | 39 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR23047206 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047207 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047208 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047209 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047210 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047211 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047212 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047213 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047214 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047215 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047216 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047217 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047218 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047219 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047220 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047221 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047222 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047223 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047224 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047225 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047226 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047227 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047228 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047229 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047230 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047231 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047232 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047233 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047234 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047235 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047236 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047237 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047238 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047239 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047240 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047241 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047242 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047243 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
| SRR23047244 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM,
StringTie quantification over 39 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora digitifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora digitifera network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora digitifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 1 available assay. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: DNase-seq (DHS).
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |