Genomic Location: Sc0000109:230465...236770
NR annotation: XP_029200250.2, myeloid differentiation primary response protein MyD88-like isoform X1 [Acropora millepora]
Species Montipora capitata · all data for this species · gene families
| CDS |
| g5486.t1 |
| Transcript |
| g5486.t1 |
| Protein |
| g5486.t1 |
| UniProt accession | Description |
|---|---|
| A8QMS7 | Myeloid differentiation primary response protein MyD88 OS=Takifugu rubripes OX=31033 GN=myd88 PE=2 SV=1 |
| B3SRQ2 | Myeloid differentiation primary response protein MyD88 OS=Salmo salar OX=8030 GN=myd88 PE=2 SV=1 |
| Q9DF60 | Myeloid differentiation primary response protein MyD88-A OS=Xenopus laevis OX=8355 GN=myd88-a PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001774 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13676 all species → | TIR_2 | TIR domain | Domain | Interproscan |
| PF00531 all species → | Death | Death domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000157 all species → | Domain | Toll/interleukin-1 receptor homology (TIR) domain | Interproscan |
| IPR011029 all species → | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR035897 all species → | Homologous_superfamily | Toll/interleukin-1 receptor homology (TIR) domain superfamily | Interproscan |
| IPR000488 all species → | Domain | Death domain | Interproscan |
| IPR017281 all species → | Family | Myeloid differentiation primary response protein MyD88 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR15079 all species → | MYD88 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0002755 all species → | Biological Process | MyD88-dependent toll-like receptor signaling pathway | Interproscan |
| GO:0043123 all species → | Biological Process | positive regulation of canonical NF-kappaB signal transduction | Interproscan |
| GO:0070976 all species → | Molecular Function | TIR domain binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K04729 | MYD88; myeloid differentiation primary response protein MyD88 | - | Alcoholic liver disease | ko04936 | deepkoala |
Transcript abundance of g5486.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organisms · ambient pH treatment | 21 | 21 | 89.48 | 111.90 | |
| whole organisms · low pH treatment | 15 | 15 | 96.87 | 133.82 | |
| whole organisms · extra low pH treatment pH treatment | 12 | 12 | 99.84 | 128.35 |
Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.