Gene detail

Detailed information of g573.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: CAB3981570.1, cell division control 6 homolog [Paramuricea clavata]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q99741	Cell division control protein 6 homolog OS=Homo sapiens OX=9606 GN=CDC6 PE=1 SV=1
O89033	Cell division control protein 6 homolog OS=Mus musculus OX=10090 GN=Cdc6 PE=1 SV=2
P41411	Cell division control protein 18 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc18 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000026 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000240 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000357 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000547 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000989 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0002347 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0002684 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0005177 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0006924 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0006934 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00078 all species →	RVT_1	Reverse transcriptase (RNA-dependent DNA polymerase)	Domain	Interproscan
PF04042 all species →	DNA_pol_E_B	DNA polymerase alpha/epsilon subunit B	Family	Interproscan
PF12796 all species →	Ank_2	Ankyrin repeats (3 copies)	Repeat	Interproscan
PF00023 all species →	Ank	Ankyrin repeat	Repeat	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF01759 all species →	NTR	UNC-6/NTR/C345C module	Domain	Interproscan
PF01392 all species →	Fz	Fz domain	Domain	Interproscan
PF17872 all species →	AAA_lid_10	AAA lid domain	Domain	Interproscan
PF13401 all species →	AAA_22	AAA domain	Domain	Interproscan
PF09079 all species →	Cdc6_C	CDC6, C terminal winged helix domain	Domain	Interproscan
PF00620 all species →	RhoGAP	RhoGAP domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR052560 all species →	Family	RNA-directed DNA polymerase, mobile element	Interproscan
IPR000477 all species →	Domain	Reverse transcriptase domain	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR016722 all species →	Family	DNA polymerase alpha, subunit B	Interproscan
IPR007185 all species →	Domain	DNA polymerase alpha/delta/epsilon, subunit B	Interproscan
IPR002110 all species →	Repeat	Ankyrin repeat	Interproscan
IPR051637 all species →	Family	Ankyrin repeat domain-containing protein 49	Interproscan
IPR036770 all species →	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR015526 all species →	Family	Frizzled/secreted frizzled-related protein	Interproscan
IPR018933 all species →	Domain	Netrin module, non-TIMP type	Interproscan
IPR036790 all species →	Homologous_superfamily	Frizzled cysteine-rich domain superfamily	Interproscan
IPR008993 all species →	Homologous_superfamily	Tissue inhibitor of metalloproteinases-like, OB-fold	Interproscan
IPR020067 all species →	Domain	Frizzled domain	Interproscan
IPR001134 all species →	Domain	Netrin domain	Interproscan
IPR035914 all species →	Homologous_superfamily	Spermadhesin, CUB domain superfamily	Interproscan
IPR040099 all species →	Family	Zinc finger ZZ-type and EF-hand domain-containing protein 1	Interproscan
IPR041083 all species →	Domain	AAA lid domain	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR015163 all species →	Domain	Cdc6, C-terminal	Interproscan
IPR049945 all species →	Domain	ORC1/DEAH AAA+ ATPase domain	Interproscan
IPR050311 all species →	Family	Origin Recognition Complex 1/Cell Division Control Protein 6	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR003593 all species →	Domain	AAA+ ATPase domain	Interproscan
IPR016314 all species →	Family	Cell division protein Cdc6/18	Interproscan
IPR001090 all species →	Domain	Ephrin receptor ligand binding domain	Interproscan
IPR008979 all species →	Homologous_superfamily	Galactose-binding-like domain superfamily	Interproscan
IPR029063 all species →	Homologous_superfamily	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Interproscan
IPR042086 all species →	Homologous_superfamily	Methyltransferase, alpha-helical capping domain	Interproscan
IPR008936 all species →	Homologous_superfamily	Rho GTPase activation protein	Interproscan
IPR000198 all species →	Domain	Rho GTPase-activating protein domain	Interproscan
IPR039102 all species →	Family	Protein FAM13	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR36688 all species →	ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR23061 all species →	DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT	Interproscan
PTHR24180 all species →	CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED	Interproscan
PTHR24342 all species →	SERINE/THREONINE-PROTEIN KINASE 17	Interproscan
PTHR11309 all species →	FRIZZLED	Interproscan
PTHR22772 all species →	NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN	Interproscan
PTHR10763 all species →	CELL DIVISION CONTROL PROTEIN 6-RELATED	Interproscan
PTHR15904 all species →	FAM13	Interproscan
PTHR19446 all species →	REVERSE TRANSCRIPTASES	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005658 all species →	Cellular Component	alpha DNA polymerase:primase complex	Interproscan
GO:0006270 all species →	Biological Process	DNA replication initiation	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0006260 all species →	Biological Process	DNA replication	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0043065 all species →	Biological Process	positive regulation of apoptotic process	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0016021 all species →	Cellular Component	membrane	Interproscan
GO:0017147 all species →	Molecular Function	Wnt-protein binding	Interproscan
GO:0035567 all species →	Biological Process	non-canonical Wnt signaling pathway	Interproscan
GO:0042813 all species →	Molecular Function	Wnt receptor activity	Interproscan
GO:0060070 all species →	Biological Process	canonical Wnt signaling pathway	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0003688 all species →	Molecular Function	DNA replication origin binding	Interproscan
GO:0033314 all species →	Biological Process	mitotic DNA replication checkpoint signaling	Interproscan
GO:0051301 all species →	Biological Process	cell division	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02213	CDC6; cell division control protein 6	-	DNA replication proteins	ko03032	deepkoala
K02321	POLA2; DNA polymerase alpha subunit B	-	DNA replication proteins	ko03032	deepkoala
K21439	ANKRD49; ankyrin repeat domain-containing protein 49	-	Signaling proteins	-	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →