Gene detail

Detailed information of g577.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_047139583.1, DDB1- and CUL4-associated factor 11 isoform X1 [Hydra vulgaris]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5E9I8	DDB1- and CUL4-associated factor 11 OS=Bos taurus OX=9913 GN=DCAF11 PE=2 SV=1
Q8TEB1	DDB1- and CUL4-associated factor 11 OS=Homo sapiens OX=9606 GN=DCAF11 PE=1 SV=1
Q5M9G8	DDB1- and CUL4-associated factor 11 OS=Rattus norvegicus OX=10116 GN=Dcaf11 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000015 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000062 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000087 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000153 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000559 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000664 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0003279 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0004251 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0004833 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0007616 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0008676 (this species only) · gene tree & orthology
Ubiquitin family	UBD\|Other\|Beta-prp · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|CDC20 · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|DWD · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03348 all species →	Serinc	Serine incorporator (Serinc)	Family	Interproscan
PF19532 all species →	TMEM131_like	Transmembrane protein 131-like	Family	Interproscan
PF00060 all species →	Lig_chan	Ligand-gated ion channel	Family	Interproscan
PF07885 all species →	Ion_trans_2	Ion channel	Family	Interproscan
PF01432 all species →	Peptidase_M3	Peptidase family M3	Family	Interproscan
PF00400 all species →	WD40	WD domain, G-beta repeat	Repeat	Interproscan
PF00385 all species →	Chromo	Chromo (CHRromatin Organisation MOdifier) domain	Domain	Interproscan
PF00665 all species →	rve	Integrase core domain	Domain	Interproscan
PF21125 all species →	MPN_2A_DUB_like	BRCA1-A complex subunit Abraxas 1 MPN domain	Domain	Interproscan
PF02037 all species →	SAP	SAP domain	Domain	Interproscan
PF00503 all species →	G-alpha	G-protein alpha subunit	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005016 all species →	Family	Serine incorporator/TMS membrane protein	Interproscan
IPR045695 all species →	Domain	Transmembrane protein 131-like, conserved domain	Interproscan
IPR039877 all species →	Family	Transmembrane protein 131-like	Interproscan
IPR001320 all species →	Domain	Ionotropic glutamate receptor, C-terminal	Interproscan
IPR013099 all species →	Domain	Potassium channel domain	Interproscan
IPR003280 all species →	Family	Two pore domain potassium channel	Interproscan
IPR045090 all species →	Family	Peptidase M3A/M3B	Interproscan
IPR001567 all species →	Domain	Peptidase M3A/M3B catalytic domain	Interproscan
IPR013087 all species →	Domain	Zinc finger C2H2-type	Interproscan
IPR000544 all species →	Family	Octanoyltransferase	Interproscan
IPR045864 all species →	Homologous_superfamily	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	Interproscan
IPR020605 all species →	Conserved_site	Octanoyltransferase, conserved site	Interproscan
IPR004143 all species →	Domain	Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain	Interproscan
IPR001680 all species →	Repeat	WD40 repeat	Interproscan
IPR051859 all species →	Family	DDB1- and CUL4-associated factor	Interproscan
IPR036322 all species →	Homologous_superfamily	WD40-repeat-containing domain superfamily	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR023780 all species →	Domain	Chromo domain	Interproscan
IPR000953 all species →	Domain	Chromo/chromo shadow domain	Interproscan
IPR023779 all species →	Conserved_site	Chromo domain, conserved site	Interproscan
IPR001584 all species →	Domain	Integrase, catalytic core	Interproscan
IPR016197 all species →	Homologous_superfamily	Chromo-like domain superfamily	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR036691 all species →	Homologous_superfamily	Endonuclease/exonuclease/phosphatase superfamily	Interproscan
IPR000477 all species →	Domain	Reverse transcriptase domain	Interproscan
IPR023238 all species →	Family	FAM175 family	Interproscan
IPR036361 all species →	Homologous_superfamily	SAP domain superfamily	Interproscan
IPR003034 all species →	Domain	SAP domain	Interproscan
IPR001019 all species →	Family	Guanine nucleotide binding protein (G-protein), alpha subunit	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR011025 all species →	Homologous_superfamily	G protein alpha subunit, helical insertion	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22050 all species →	RW1 PROTEIN HOMOLOG	Interproscan
PTHR11003 all species →	POTASSIUM CHANNEL, SUBFAMILY K	Interproscan
PTHR11804 all species →	PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED	Interproscan
PTHR10993 all species →	OCTANOYLTRANSFERASE	Interproscan
PTHR19847 all species →	DDB1- AND CUL4-ASSOCIATED FACTOR 11	Interproscan
PTHR46585 all species →	INTEGRASE CORE DOMAIN CONTAINING PROTEIN	Interproscan
PTHR46670 all species →	ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN	Interproscan
PTHR31728 all species →	ABRAXAS FAMILY MEMBER	Interproscan
PTHR10218 all species →	GTP-BINDING PROTEIN ALPHA SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0015276 all species →	Molecular Function	ligand-gated monoatomic ion channel activity	Interproscan
GO:0005267 all species →	Molecular Function	potassium channel activity	Interproscan
GO:0005887 all species →	Cellular Component	plasma membrane	Interproscan
GO:0015271 all species →	Molecular Function	outward rectifier potassium channel activity	Interproscan
GO:0022841 all species →	Molecular Function	potassium ion leak channel activity	Interproscan
GO:0030322 all species →	Biological Process	stabilization of membrane potential	Interproscan
GO:0071805 all species →	Biological Process	potassium ion transmembrane transport	Interproscan
GO:0004222 all species →	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0005758 all species →	Cellular Component	mitochondrial intermembrane space	Interproscan
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0006518 all species →	Biological Process	peptide metabolic process	Interproscan
GO:0009249 all species →	Biological Process	protein lipoylation	Interproscan
GO:0033819 all species →	Molecular Function	lipoyl(octanoyl) transferase activity	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0036211 all species →	Biological Process	protein modification process	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0043161 all species →	Biological Process	proteasome-mediated ubiquitin-dependent protein catabolic process	Interproscan
GO:0080008 all species →	Cellular Component	Cul4-RING E3 ubiquitin ligase complex	Interproscan
GO:0015074 all species →	Biological Process	DNA integration	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0031593 all species →	Molecular Function	polyubiquitin modification-dependent protein binding	Interproscan
GO:0003924 all species →	Molecular Function	GTPase activity	Interproscan
GO:0007186 all species →	Biological Process	G protein-coupled receptor signaling pathway	Interproscan
GO:0019001 all species →	Molecular Function	guanyl nucleotide binding	Interproscan
GO:0031683 all species →	Molecular Function	G-protein beta/gamma-subunit complex binding	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0001664 all species →	Molecular Function	G protein-coupled receptor binding	Interproscan
GO:0005834 all species →	Cellular Component	heterotrimeric G-protein complex	Interproscan
GO:0007188 all species →	Biological Process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00986	ltrA; RNA-directed DNA polymerase	EC:2.7.7.49	Enzymes with EC numbers	-	deepkoala
K04630	GNAI; guanine nucleotide-binding protein G(i) subunit alpha	-	GTP-binding proteins	ko04031	deepkoala
K11801	DCAF11; DDB1- and CUL4-associated factor 11	-	Ubiquitin system	ko04121	deepkoala
K23735	LIPT2, LIP2; lipoyl(octanoyl) transferase 2	EC:2.3.1.181	Lipoic acid metabolism	ko00785	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →