Genomic Location: :...
NR annotation: XP_020632049.1, cytochrome P450 27C1-like [Orbicella faveolata]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q09128 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Cyp24a1 PE=1 SV=1 | ||||
| Q02318 | Sterol 26-hydroxylase, mitochondrial OS=Homo sapiens OX=9606 GN=CYP27A1 PE=1 SV=1 | ||||
| Q64441 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial OS=Mus musculus OX=10090 GN=Cyp24a1 PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | Nrf1 |
| Transcription Factors Family | zf-LITAF-like |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF10601 | zf-LITAF-like | LITAF-like zinc ribbon domain | Family | Interproscan |
| PF01163 | RIO1 | RIO1 family | Family | Interproscan |
| PF00067 | p450 | Cytochrome P450 | Domain | Interproscan |
| PF00549 | Ligase_CoA | CoA-ligase | Domain | Interproscan |
| PF08442 | ATP-grasp_2 | ATP-grasp domain | Domain | Interproscan |
| PF00225 | Kinesin | Kinesin motor domain | Domain | Interproscan |
| PF10491 | Nrf1_DNA-bind | NLS-binding and DNA-binding and dimerisation domains of Nrf1 | Family | Interproscan |
| PF10492 | Nrf1_activ_bdg | Nrf1 activator activation site binding domain | Domain | Interproscan |
| PF00180 | Iso_dh | Isocitrate/isopropylmalate dehydrogenase | Domain | Interproscan |
| PF00462 | Glutaredoxin | Glutaredoxin | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006629 | Domain | LPS-induced tumour necrosis factor alpha factor | Interproscan |
| IPR037519 | Family | LITAF domain containing protein | Interproscan |
| IPR017407 | Family | Serine/threonine-protein kinase Rio1 | Interproscan |
| IPR018935 | Conserved_site | RIO kinase, conserved site | Interproscan |
| IPR051272 | Family | RIO-type Ser/Thr kinase | Interproscan |
| IPR000687 | Domain | RIO kinase | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR017972 | Conserved_site | Cytochrome P450, conserved site | Interproscan |
| IPR036396 | Homologous_superfamily | Cytochrome P450 superfamily | Interproscan |
| IPR001128 | Family | Cytochrome P450 | Interproscan |
| IPR002401 | Family | Cytochrome P450, E-class, group I | Interproscan |
| IPR050479 | Family | Cytochrome P450, families 11 and 27 | Interproscan |
| IPR005809 | Family | Succinate--CoA ligase-like, beta subunit | Interproscan |
| IPR034723 | Family | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Interproscan |
| IPR013815 | Homologous_superfamily | ATP-grasp fold, subdomain 1 | Interproscan |
| IPR016102 | Homologous_superfamily | Succinyl-CoA synthetase-like | Interproscan |
| IPR005811 | Domain | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | Interproscan |
| IPR017866 | Conserved_site | Succinyl-CoA synthetase, beta subunit, conserved site | Interproscan |
| IPR011761 | Domain | ATP-grasp fold | Interproscan |
| IPR013650 | Domain | ATP-grasp fold, succinyl-CoA synthetase-type | Interproscan |
| IPR001752 | Domain | Kinesin motor domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR027640 | Family | Kinesin-like protein | Interproscan |
| IPR019821 | Conserved_site | Kinesin motor domain, conserved site | Interproscan |
| IPR036961 | Homologous_superfamily | Kinesin motor domain superfamily | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR019525 | Domain | Nuclear respiratory factor 1, NLS/DNA-binding, dimerisation domain | Interproscan |
| IPR039142 | Family | NRF1/Ewg family | Interproscan |
| IPR024084 | Domain | Isopropylmalate dehydrogenase-like domain | Interproscan |
| IPR019818 | Conserved_site | Isocitrate/isopropylmalate dehydrogenase, conserved site | Interproscan |
| IPR004434 | Family | Isocitrate dehydrogenase NAD-dependent | Interproscan |
| IPR011899 | Domain | Glutaredoxin, eukaryotic/virial | Interproscan |
| IPR036249 | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR002109 | Domain | Glutaredoxin | Interproscan |
| IPR014025 | Domain | Glutaredoxin subgroup | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23292 | LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR | Interproscan |
| PTHR45723 | SERINE/THREONINE-PROTEIN KINASE RIO1 | Interproscan |
| PTHR24279 | - | Interproscan |
| PTHR11815 | SUCCINYL-COA SYNTHETASE BETA CHAIN | Interproscan |
| PTHR47969 | CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED | Interproscan |
| PTHR20338 | NUCLEAR RESPIRATORY FACTOR 1 | Interproscan |
| PTHR11835 | DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE | Interproscan |
| PTHR45694 | GLUTAREDOXIN 2 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0030490 | Biological Process | maturation of SSU-rRNA | Interproscan |
| GO:0030688 | Cellular Component | preribosome, small subunit precursor | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0004497 | Molecular Function | monooxygenase activity | Interproscan |
| GO:0020037 | Molecular Function | heme binding | Interproscan |
| GO:0005743 | Cellular Component | mitochondrial inner membrane | Interproscan |
| GO:0006700 | Biological Process | C21-steroid hormone biosynthetic process | Interproscan |
| GO:0006704 | Biological Process | glucocorticoid biosynthetic process | Interproscan |
| GO:0008203 | Biological Process | cholesterol metabolic process | Interproscan |
| GO:0034650 | Biological Process | cortisol metabolic process | Interproscan |
| GO:0071375 | Biological Process | cellular response to peptide hormone stimulus | Interproscan |
| GO:0006099 | Biological Process | tricarboxylic acid cycle | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0004775 | Molecular Function | succinate-CoA ligase (ADP-forming) activity | Interproscan |
| GO:0006104 | Biological Process | succinyl-CoA metabolic process | Interproscan |
| GO:0042709 | Cellular Component | succinate-CoA ligase complex | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0003777 | Molecular Function | microtubule motor activity | Interproscan |
| GO:0007018 | Biological Process | microtubule-based movement | Interproscan |
| GO:0008017 | Molecular Function | microtubule binding | Interproscan |
| GO:0005875 | Cellular Component | microtubule associated complex | Interproscan |
| GO:0007052 | Biological Process | mitotic spindle organization | Interproscan |
| GO:0051231 | Biological Process | spindle elongation | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0003700 | Molecular Function | DNA-binding transcription factor activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0006102 | Biological Process | isocitrate metabolic process | Interproscan |
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0015038 | Molecular Function | glutathione disulfide oxidoreductase activity | Interproscan |
| GO:0034599 | Biological Process | cellular response to oxidative stress | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K03676 | grxC, GLRX, GLRX2; glutaredoxin 3 | - | Chromosome and associated proteins | ko03036 | deepkoala |
| Citrate cycle (TCA cycle) | ko00020 | deepkoala | |||
| Mitochondrial biogenesis | ko03029 | deepkoala | |||
| Messenger RNA biogenesis | ko03019 | deepkoala | |||
| Ribosome biogenesis | ko03009 | deepkoala | |||
| Exosome | ko04147 | deepkoala | |||
| Chaperones and folding catalysts | ko03110 | deepkoala |