Gene detail

Detailed information of g6012.t1 in Montipora capitata

Genomic Location: Sc0000125:148960...170985
NR annotation: XP_015759044.1, PREDICTED: inactive tyrosine-protein kinase transmembrane receptor ROR1-like [Acropora digitifera]
Species Montipora capitata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

g6012.t1

atggggctgatatcgctgaacagtctgttctgggctttttctttatggattttttgcgcgacctctcttttgggcttcaagaccaagcgttctctggaatcccctagctcccatttttcagaccacacaaacgtttgtccagactgcaaagcaccagtgtttgacaagcctttgaacaatgaaactgtcagtaagggtggcagagcaacattcaaatgttatgcaagtggcaatccacttccagatatcatgtggtacaggcatggaaaaccaatcccagatgaaagtggattatatattgtggcgagaaggagttggggagcgagattgaggatccgtgatgtgactctgaatgacgcaggagcttatctttgtgtggccaacaattctgaaggaacagcaagcgcagaagctttcctggttgtcaatgtaaccttgaagccctcctcggcagagactgagccaacacttgaagctgcatcaccagtaacagcccagccttctgtgaaatctgacagacccattacgaaacaagaatttttgcctcctgattataagcagtcaaatcctccaggatcagctgatgacggtgggacacataaggaaccgaccacaagcgatctggatataccgacacctccagctttctcagacaacggcagttgcgtgaaatacaatgggactgtttgcagcaaggtgttaagaggagcccttgtgtatatacacagctttgaaaaactggaaaacatcgagcgaaaactgagcaccgcttacgacaatatacgaacttataaagaaatcagccgtcgatgtcggcccttcgtacaacctcttctttgtcattaccagttcccgagctgtgataggagttattccaaaccgaagaagatggaaatttgctacgaggagtgcgaagtcttgcgaaccaagatttgcccgaaggagtataaaattgccgagagtcaatccctacaagatgtgctgtttccagtttgttcgtctttgcctcgtagcaataccaaggaaggcaagaattgtattaagcttggagttaatgattctgggattcaaaagcccaaaaaacccgtcatcagaaaagtgtcttcagtcaccgtttgctacacaaacactggacaagacttccgcgccaacgttagcgtaacagagaaaggttatgtttgtcaagcatggaattccaccaaacctcatttccacattatctcacccaaagaccaccccgagatcggaggcgggcacaacttttgtagaaatccaggcggacagaaaaagcgaccatggtgcttcactacagacgaatcagccgaatttgactactgtgatattcccagatgtggtgagagaatacttggagaggatacaccaccggtagaatttgtcagtgttctttacaccgtcattccttgtctcctcttcgccatcttgttcgcgtcagttgtgattttcgtctgttggagatgtcgcaaacaaatcatgcaccaagcggaacagtccgcagcaattcctctcgtgccggtcgttggtaagcctgtgatgaaagagatgcgatatgagaccgtcagattcgtaaaagacttaggagaaggagaatttggcaaactctacatgggcgaggtagttgaaaaagccgatggtgtgcaagtagctcgacccattgtcgccaaagtcctgcgaaagagctcgtcctcgagttaccgtgatagttttctgaatcaagcggagacttggtccaactttagccatcccaacgtaatggctataatcggggtctgttataacggtccaccgacgtgcattttgtacgaatgcgtcgaatatgggacgttatacgattacctcgtcgagaactcgccggcacagagcccagtcgatgtggacgacgacgatccgggccatctaacttaccacgaacagttatcgattgctattcaagttgcggcaggaatgaattacctctctcagcataactatatccatggcgacttagccgcacgaaattgtatggtgggccctcgtatgatagttaaaataacagacgtggctctaaaccgaagtccgttttcaagagactatcaaaggtccgctaacagacctccgatgccccttcgctggatggcaccagaaggggtccttaattataggttcactgtagagaccgatatttggtcctttggagtgttgctgtgggagatcttttctttcggttgcagaccccatgataggcacagcgacaaagaggtcacagaacttatcagggaacacatattgcttccttgtccaagcgactgtccgaatacggtttttgtactcatgaaagggtgctgggatattttgcctccgagcaggccgcgttttagtacaatttatacgcatctttgcgcgttgaggtctgaccccaacgggcttgtgcctccagctgacgttagtgtctccggagattatttcgatgtttaa

Transcript

g6012.t1

ATGGGGCTGATATCGCTGAACAGTCTGTTCTGGGCTTTTTCTTTATGGATTTTTTGCGCGACCTCTCTTTTGGGCTTCAAGACCAAGCGTTCTCTGGAATCCCCTAGCTCCCATTTTTCAGACCACACAAACGTTTGTCCAGACTGCAAAGCACCAGTGTTTGACAAGCCTTTGAACAATGAAACTGTCAGTAAGGGTGGCAGAGCAACATTCAAATGTTATGCAAGTGGCAATCCACTTCCAGATATCATGTGGTACAGGCATGGAAAACCAATCCCAGATGAAAGTGGATTATATATTGTGGCGAGAAGGAGTTGGGGAGCGAGATTGAGGATCCGTGATGTGACTCTGAATGACGCAGGAGCTTATCTTTGTGTGGCCAACAATTCTGAAGGAACAGCAAGCGCAGAAGCTTTCCTGGTTGTCAATGtAACCTTGAAGCCCTCCTCGGCAGAGACTGAGCCAACACTTGAAGCTGCATCACCAGTAACAGCCCAGCCTTCTGTGAAATCTGACAGACCCATTACGAAACAAGAATTTTTGCCTCCTGATTATAAGCAGTCAAATCCTCCAGGATCAGCTGATGACGGTGGGACACATAAGGAACCGACCACAAGCGATCTGGATATACCGACACCTCCAGCTTTCTCAGACAACGGCAGTTGCGTGAAATACAATGGGACTGTTTGCAGCAAGGTGTTAAGAGGAGCCCTTGTGTATATACACAGCTTTGAAAAACTGGAAAACATCGAGCGAAAACTGAGCACCGCTTACGACAATATACGAACTTATAAAGAAATCAGCCGTCGATGTCGGCCCTTCGTACAACCTCTTCTTTGTCATTACCAGTTCCCGAGCTGTGATAGGAGTTATTCCAAACCGAAGAAGATGGAAATTTGCTACGAGGAGTGCGAAGTCTTGCGAACCAAGATTTGCCCGAAGGAGTATAAAATTGCCGAGAGTCAATCCCTACAAGATGTGCTGTTTCCAGTTTGTTCGTCTTTGCCTCGTAGCAATACCAAGGAAGGCAAGAATTGTATTAAGCTTGGAGTTAATGATTCTGGGATTCAAAAGCCCAAAAAACCCGTCATCAGAAAAGTGTCTTCAGTCACCGTTTGCTACACAAACACTGGACAAGACTTCCGCGCCAACGTTAGCGTAACAGAGAAAGGTTATGTTTGTCAAGCATGGAATTCCACCAAACCTCATTTCCACATTATCTCACCCAAAGACCACCCCGAGATCGGAGGCGGGCACAACTTTTGTAGAAATCCAGGCGGACAGAAAAAGCGACCATGGTGCTTCACTACAGACGAATCAGCCGAATTTGACTACTGTGATATTCCCAGATGTGGTGAGAGAATACTTGGAGAGGATACACCACCGGTAGAATTTGTCAGTGTTCTTTACACCGTCATTCCTTGTCTCCTCTTCGCCATCTTGTTCGCGTCAGTTGTGATTTTCGTCTGTTGGAGATGTCGCAAACAAATCATGCACCAAGCGGAACAGTCCGCAGCAATTCCTCTCGTGCCGGTCGTTGGTAAGCCTGTGATGAAAGAGATGCGATATGAGACCGTCAGATTCGTAAAAGACTTAGGAGAAGGAGAATTTGGCAAACTCTACATGGGCGAGGTAGTTGAAAAAGCCGATGGTGTGCAAGTAGCTCGACCCATTGTCGCCAAAGTCCTGCGAAAGAGCTCGTCCTCGAGTTACCGTGATAGTTTTCTGAATCAAGCGGAGACTTGGTCCAACTTTAGCCATCCCAACGTAATGGCTATAATCGGGGTCTGTTATAACGGTCCACCGACGTGCATTTTGTACGAATGCGTCGAATATGGGACGTTATACGATTACCTCGTCGAGAACTCGCCGGCACAGAGCCCAGTCGATGTGGACGACGACGATCCGGGCCATCTAACTTACCACGAACAGTTATCGATTGCTATTCAAGTTGCGGCAGGAATGAATTACCTCTCTCAGCATAACTATATCCATGGCGACTTAGCCGCACGAAATTGTATGGTGGGCCCTCGTATGATAGTTAAAATAACAGACGTGGCTCTAAACCGAAGTCCGTTTTCAAGAGACTATCAAAGGTCCGCTAACAGACCTCCGATGCCCCTTCGCTGGATGGCACCAGAAGGGGTCCTTAATTATAGGTTCACTGTAGAGACCGATATTTGGTCCTTTGGAGTGTTGCTGTGGGAGATCTTTTCTTTCGGTTGCAGACCCCATGATAGGCACAGCGACAAAGAGGTCACAGAACTTATCAGGGAACACATATTGCTTCCTTGTCCAAGCGACTGTCCGAATACGGTTTTTGTACTCATGAAAGGGTGCTGGGATATTTTGCCTCCGAGCAGGCCGCGTTTTAGTACAATTTATACGCATCTTTGCGCGTTGAGGTCTGACCCCAACGGGCTTGTGCCTCCAGCTGACGTTAGTGTCTCCGGAGATTATTTCGATGTTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q01973	Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Homo sapiens OX=9606 GN=ROR1 PE=1 SV=2
Q9Z139	Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Mus musculus OX=10090 GN=Ror1 PE=2 SV=2
Q01974	Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo sapiens OX=9606 GN=ROR2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001743 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07679 all species →	I-set	Immunoglobulin I-set domain	Domain	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan
PF01392 all species →	Fz	Fz domain	Domain	Interproscan
PF00051 all species →	Kringle	Kringle domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR018056 all species →	Conserved_site	Kringle, conserved site	Interproscan
IPR003599 all species →	Domain	Immunoglobulin subtype	Interproscan
IPR000001 all species →	Domain	Kringle	Interproscan
IPR036179 all species →	Homologous_superfamily	Immunoglobulin-like domain superfamily	Interproscan
IPR013806 all species →	Homologous_superfamily	Kringle-like fold	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR036790 all species →	Homologous_superfamily	Frizzled cysteine-rich domain superfamily	Interproscan
IPR007110 all species →	Domain	Immunoglobulin-like domain	Interproscan
IPR013098 all species →	Domain	Immunoglobulin I-set	Interproscan
IPR041775 all species →	Domain	Ror-like, cysteine-rich domain	Interproscan
IPR003598 all species →	Domain	Immunoglobulin subtype 2	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR013783 all species →	Homologous_superfamily	Immunoglobulin-like fold	Interproscan
IPR050122 all species →	Family	Receptor Tyrosine Kinase	Interproscan
IPR038178 all species →	Homologous_superfamily	Kringle superfamily	Interproscan
IPR020067 all species →	Domain	Frizzled domain	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24416 all species →	TYROSINE-PROTEIN KINASE RECEPTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004714 all species →	Molecular Function	transmembrane receptor protein tyrosine kinase activity	Interproscan
GO:0005887 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007169 all species →	Biological Process	cell surface receptor protein tyrosine kinase signaling pathway	Interproscan
GO:0007275 all species →	Biological Process	multicellular organism development	Interproscan
GO:0010976 all species →	Biological Process	positive regulation of neuron projection development	Interproscan
GO:0014068 all species →	Biological Process	obsolete positive regulation of phosphatidylinositol 3-kinase signaling	Interproscan
GO:0017147 all species →	Molecular Function	Wnt-protein binding	Interproscan
GO:0033674 all species →	Biological Process	positive regulation of kinase activity	Interproscan
GO:0043235 all species →	Cellular Component	receptor complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05122	ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1	EC:2.7.10.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g6012.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

47TPM > 0

3Conditions

42.8Max TPM

9.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organisms · ambient pH treatment	21	21	10.06	41.50
whole organisms · low pH treatment	15	14	7.80	21.44
whole organisms · extra low pH treatment pH treatment	12	12	12.24	42.84

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR11452222	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	41.50
SRR11452230	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	35.76
SRR11452228	whole organisms · ambient pH treatment	whole organisms	planulae	ambient pH treatment	SRP254626	30.57
SRR11452232	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	21.50
SRR11452231	whole organisms · ambient pH treatment	whole organisms	blastula	ambient pH treatment	SRP254626	8.84
SRR11452252	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	8.23
SRR11452246	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	7.92
SRR11452250	whole organisms · ambient pH treatment	whole organisms	prawn chip	ambient pH treatment	SRP254626	7.70
SRR11452234	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	6.45
SRR11452259	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	5.31
SRR11452254	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	4.66
SRR11452263	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	4.11
SRR11452242	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	4.06
SRR11452251	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	3.72
SRR11452233	whole organisms · ambient pH treatment	whole organisms	morula	ambient pH treatment	SRP254626	3.60
SRR11452240	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	3.56
SRR11452260	whole organisms · ambient pH treatment	whole organisms	cleavage	ambient pH treatment	SRP254626	3.55
SRR11452217	whole organisms · ambient pH treatment	whole organisms	fertilized embryo	ambient pH treatment	SRP254626	3.25
SRR11452262	whole organisms · ambient pH treatment	whole organisms	egg	ambient pH treatment	SRP254626	3.20
SRR11452243	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	2.51
SRR11452237	whole organisms · ambient pH treatment	whole organisms	gastrula	ambient pH treatment	SRP254626	1.35
SRR11452221	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	21.44
SRR11452223	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	20.11
SRR11452224	whole organisms · low pH treatment	whole organisms	planulae	low pH treatment	SRP254626	18.64
SRR11452245	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	9.20
SRR11452247	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	9.19
SRR11452249	whole organisms · low pH treatment	whole organisms	prawn chip	low pH treatment	SRP254626	7.02
SRR11452229	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	6.50
SRR11452253	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	6.38
SRR11452218	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	5.56
SRR11452255	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	3.69
SRR11452238	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	2.95
SRR11452258	whole organisms · low pH treatment	whole organisms	cleavage	low pH treatment	SRP254626	2.46
SRR11452236	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	2.21
SRR11452241	whole organisms · low pH treatment	whole organisms	gastrula	low pH treatment	SRP254626	1.68
SRR11452216	whole organisms · low pH treatment	whole organisms	fertilized embryo	low pH treatment	SRP254626	0.00
SRR11452227	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	42.84
SRR11452225	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	38.76
SRR11452226	whole organisms · extra low pH treatment pH treatment	whole organisms	planulae	extra low pH treatment pH treatment	SRP254626	28.50
SRR11452248	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	10.28
SRR11452244	whole organisms · extra low pH treatment pH treatment	whole organisms	prawn chip	extra low pH treatment pH treatment	SRP254626	7.55
SRR11452257	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	4.44
SRR11452219	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	4.42
SRR11452239	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	2.87
SRR11452235	whole organisms · extra low pH treatment pH treatment	whole organisms	gastrula	extra low pH treatment pH treatment	SRP254626	2.80
SRR11452256	whole organisms · extra low pH treatment pH treatment	whole organisms	cleavage	extra low pH treatment pH treatment	SRP254626	2.47
SRR11452261	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	1.20
SRR11452220	whole organisms · extra low pH treatment pH treatment	whole organisms	fertilized embryo	extra low pH treatment pH treatment	SRP254626	0.75

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.