Genomic Location: chr3Alt:11437348...11469060
NR annotation: XP_015777439.1, PREDICTED: adhesion G protein-coupled receptor A3-like isoform X2 [Acropora digitifera]
Species Acropora digitifera · all data for this species · gene families
| CDS |
| g6043.t1 |
| Transcript |
| chr3Alt.g6043.t1 |
| Protein |
| chr3Alt.g6043.t1 |
| UniProt accession | Description |
|---|---|
| E7FBY6 | Adhesion G protein-coupled receptor A2 OS=Danio rerio OX=7955 GN=adgra2 PE=1 SV=2 |
| Q5IXF8 | Glucagon-like peptide 2 receptor OS=Mus musculus OX=10090 GN=Glp2r PE=2 SV=2 |
| O95838 | Glucagon-like peptide 2 receptor OS=Homo sapiens OX=9606 GN=GLP2R PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13855 all species → | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF07679 all species → | I-set | Immunoglobulin I-set domain | Domain | Interproscan |
| PF00002 all species → | 7tm_2 | 7 transmembrane receptor (Secretin family) | Family | Interproscan |
| PF02793 all species → | HRM | Hormone receptor domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001611 all species → | Repeat | Leucine-rich repeat | Interproscan |
| IPR032675 all species → | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR001879 all species → | Domain | GPCR, family 2, extracellular hormone receptor domain | Interproscan |
| IPR036179 all species → | Homologous_superfamily | Immunoglobulin-like domain superfamily | Interproscan |
| IPR000483 all species → | Domain | Cysteine-rich flanking region, C-terminal | Interproscan |
| IPR017981 all species → | Domain | GPCR, family 2-like, 7TM | Interproscan |
| IPR051963 all species → | Family | Adhesion G protein-coupled receptor A | Interproscan |
| IPR013098 all species → | Domain | Immunoglobulin I-set | Interproscan |
| IPR036445 all species → | Homologous_superfamily | GPCR family 2, extracellular hormone receptor domain superfamily | Interproscan |
| IPR046338 all species → | Homologous_superfamily | GAIN domain superfamily | Interproscan |
| IPR000832 all species → | Family | GPCR, family 2, secretin-like | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR003599 all species → | Domain | Immunoglobulin subtype | Interproscan |
| IPR007110 all species → | Domain | Immunoglobulin-like domain | Interproscan |
| IPR003591 all species → | Repeat | Leucine-rich repeat, typical subtype | Interproscan |
| IPR003598 all species → | Domain | Immunoglobulin subtype 2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45930 all species → | G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0004930 all species → | Molecular Function | G protein-coupled receptor activity | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0004888 all species → | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| GO:0007166 all species → | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007186 all species → | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K08462 | ADGRA3, GPR125; adhesion G protein-coupled receptor A3 | - | G protein-coupled receptors | ko04030 | deepkoala |
Transcript abundance of g6043.t1 across 39 RNA-seq samples of Acropora digitifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Coral branch | 39 | 39 | 51.06 | 71.42 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR23047226 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 71.42 |
| SRR23047222 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 67.94 |
| SRR23047210 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 62.38 |
| SRR23047221 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 61.65 |
| SRR23047208 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 61.31 |
| SRR23047209 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 60.75 |
| SRR23047223 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 60.54 |
| SRR23047211 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 57.86 |
| SRR23047242 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 57.72 |
| SRR23047219 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 57.49 |
| SRR23047239 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 57.37 |
| SRR23047216 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 57.31 |
| SRR23047220 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 56.04 |
| SRR23047243 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 55.77 |
| SRR23047213 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 55.66 |
| SRR23047232 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 55.46 |
| SRR23047237 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 52.74 |
| SRR23047235 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 52.32 |
| SRR23047207 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 50.95 |
| SRR23047233 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 50.33 |
| SRR23047206 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 49.23 |
| SRR23047231 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 48.41 |
| SRR23047224 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 48.40 |
| SRR23047241 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 48.25 |
| SRR23047229 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 48.15 |
| SRR23047234 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 47.75 |
| SRR23047214 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 46.79 |
| SRR23047227 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 46.00 |
| SRR23047217 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 45.82 |
| SRR23047215 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 43.65 |
| SRR23047218 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 42.81 |
| SRR23047240 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 42.76 |
| SRR23047225 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 41.28 |
| SRR23047236 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 40.44 |
| SRR23047228 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 39.16 |
| SRR23047244 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 38.24 |
| SRR23047238 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 37.81 |
| SRR23047230 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 36.79 |
| SRR23047212 | Coral branch | Coral branch | adult | not recorded | SRP416931 | 36.76 |
Source: CnidoSite RNA-seq expression matrices (ADIGI_TPM,
StringTie quantification over 39 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora digitifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 26 | g8056.t1 | 0.863151593967574 |
| Negatively correlated | 17 | g19588.t1 | -0.734769516377262 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora digitifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|
No called peak overlaps this gene in 1 available assay. Either the gene is not near an accessible or marked region in those samples, or it is not represented in the peak caller’s annotation.
Browse the full epigenomic landscape of this species: DNase-seq (DHS).
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |