Genomic Location: :...
NR annotation: XP_032816043.1, mediator of RNA polymerase II transcription subunit 25 isoform X7 [Petromyzon marinus]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9VDR1 | Mediator of RNA polymerase II transcription subunit 25 OS=Drosophila melanogaster OX=7227 GN=MED25 PE=2 SV=1 |
| Q8VCB2 | Mediator of RNA polymerase II transcription subunit 25 OS=Mus musculus OX=10090 GN=Med25 PE=1 SV=1 |
| Q71SY5 | Mediator of RNA polymerase II transcription subunit 25 OS=Homo sapiens OX=9606 GN=MED25 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05208 | ALG3 | ALG3 protein | Family | Interproscan |
| PF11232 | Med25 | Mediator complex subunit 25 PTOV activation and synapsin 2 | Domain | Interproscan |
| PF11265 | Med25_VWA | Mediator complex subunit 25 von Willebrand factor type A | Family | Interproscan |
| PF00009 | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| PF00884 | Sulfatase | Sulfatase | Family | Interproscan |
| PF13843 | DDE_Tnp_1_7 | Transposase IS4 | Domain | Interproscan |
| PF00665 | rve | Integrase core domain | Domain | Interproscan |
| PF05577 | Peptidase_S28 | Serine carboxypeptidase S28 | Domain | Interproscan |
| PF13417 | GST_N_3 | Glutathione S-transferase, N-terminal domain | Domain | Interproscan |
| PF00043 | GST_C | Glutathione S-transferase, C-terminal domain | Domain | Interproscan |
| PF05649 | Peptidase_M13_N | Peptidase family M13 | Family | Interproscan |
| PF02984 | Cyclin_C | Cyclin, C-terminal domain | Domain | Interproscan |
| PF20700 | Mutator | Mutator-like transposase | Domain | Interproscan |
| PF14658 | EF-hand_9 | EF-hand domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR007873 | Family | Glycosyltransferase, ALG3 | Interproscan |
| IPR038196 | Homologous_superfamily | Mediator complex subunit 25, PTOV domain superfamily | Interproscan |
| IPR021394 | Domain | Mediator complex, subunit Med25, PTOV domain | Interproscan |
| IPR021419 | Domain | Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain | Interproscan |
| IPR002035 | Domain | von Willebrand factor, type A | Interproscan |
| IPR036465 | Homologous_superfamily | von Willebrand factor A-like domain superfamily | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR031157 | Conserved_site | Tr-type G domain, conserved site | Interproscan |
| IPR000795 | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR006297 | Family | Elongation factor 4 | Interproscan |
| IPR017850 | Homologous_superfamily | Alkaline-phosphatase-like, core domain superfamily | Interproscan |
| IPR047115 | Family | Arylsulfatase B | Interproscan |
| IPR000917 | Domain | Sulfatase, N-terminal | Interproscan |
| IPR029526 | Domain | PiggyBac transposable element-derived protein | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR042269 | Homologous_superfamily | Serine carboxypeptidase S28, SKS domain | Interproscan |
| IPR008758 | Family | Peptidase S28 | Interproscan |
| IPR029058 | Homologous_superfamily | Alpha/Beta hydrolase fold | Interproscan |
| IPR004045 | Domain | Glutathione S-transferase, N-terminal | Interproscan |
| IPR004046 | Domain | Glutathione S-transferase, C-terminal | Interproscan |
| IPR036249 | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR050983 | Family | Glutathione S-transferase Omega/HSP26 | Interproscan |
| IPR010987 | Domain | Glutathione S-transferase, C-terminal-like | Interproscan |
| IPR040079 | Family | Glutathione transferase family | Interproscan |
| IPR036282 | Homologous_superfamily | Glutathione S-transferase, C-terminal domain superfamily | Interproscan |
| IPR008753 | Domain | Peptidase M13, N-terminal domain | Interproscan |
| IPR000718 | Family | Peptidase M13 | Interproscan |
| IPR042089 | Homologous_superfamily | Peptidase M13, domain 2 | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR036915 | Homologous_superfamily | Cyclin-like superfamily | Interproscan |
| IPR013763 | Domain | Cyclin-like domain | Interproscan |
| IPR043198 | Family | Cyclin/Cyclin-like subunit Ssn8 | Interproscan |
| IPR004367 | Domain | Cyclin, C-terminal domain | Interproscan |
| IPR049012 | Domain | Mutator-like transposase domain | Interproscan |
| IPR039508 | Domain | Protein KASH5, EF-hand-like domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12646 | NOT56 - RELATED | Interproscan |
| PTHR12433 | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | Interproscan |
| PTHR43512 | TRANSLATION FACTOR GUF1-RELATED | Interproscan |
| PTHR10342 | ARYLSULFATASE | Interproscan |
| PTHR46599 | PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR11010 | PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED | Interproscan |
| PTHR43968 | - | Interproscan |
| PTHR11733 | ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED | Interproscan |
| PTHR10026 | CYCLIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000030 | Molecular Function | mannosyltransferase activity | Interproscan |
| GO:0005783 | Cellular Component | endoplasmic reticulum | Interproscan |
| GO:0006486 | Biological Process | protein glycosylation | Interproscan |
| GO:0052925 | Molecular Function | dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity | Interproscan |
| GO:0005667 | Cellular Component | transcription regulator complex | Interproscan |
| GO:0016592 | Cellular Component | mediator complex | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0003924 | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0043022 | Molecular Function | ribosome binding | Interproscan |
| GO:0045727 | Biological Process | positive regulation of translation | Interproscan |
| GO:0097177 | Molecular Function | mitochondrial ribosome binding | Interproscan |
| GO:0008484 | Molecular Function | sulfuric ester hydrolase activity | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0070008 | Molecular Function | serine-type exopeptidase activity | Interproscan |
| GO:0005764 | Cellular Component | lysosome | Interproscan |
| GO:0005768 | Cellular Component | endosome | Interproscan |
| GO:0008239 | Molecular Function | dipeptidyl-peptidase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0016485 | Biological Process | protein processing | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| GO:0016538 | Molecular Function | cyclin-dependent protein serine/threonine kinase regulator activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00799 | GST, gst; glutathione S-transferase | EC:2.5.1.18 | Transcription machinery | ko03021 | deepkoala |
| Peptidases and inhibitors | ko01002 | deepkoala | |||
| Transporters | ko02000 | deepkoala |