Detailed information of g6367.t1 in Montipora capitata

Genomic Location: Sc0000135:168492...179070
NR annotation: XP_029196146.2, LOW QUALITY PROTEIN: cyclin-dependent kinase 12-like [Acropora millepora]
Species Montipora capitata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
B5DE93Cyclin-dependent kinase 12 OS=Xenopus tropicalis OX=8364 GN=cdk12 PE=2 SV=1
Q14AX6Cyclin-dependent kinase 12 OS=Mus musculus OX=10090 GN=Cdk12 PE=1 SV=2
Q3MJK5Cyclin-dependent kinase 12 OS=Rattus norvegicus OX=10116 GN=Cdk12 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001984 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00069
all species →		PkinaseProtein kinase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000719
all species →		DomainProtein kinase domainInterproscan
IPR011009
all species →		Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR008271
all species →		Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR050108
all species →		FamilyCyclin-dependent kinaseInterproscan
IPR017441
all species →		Binding_siteProtein kinase, ATP binding siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR24056
all species →		CELL DIVISION PROTEIN KINASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004672
all species →		Molecular Functionprotein kinase activityInterproscan
GO:0005524
all species →		Molecular FunctionATP bindingInterproscan
GO:0006468
all species →		Biological Processprotein phosphorylationInterproscan
GO:0000307
all species →		Cellular Componentcyclin-dependent protein kinase holoenzyme complexInterproscan
GO:0004674
all species →		Molecular Functionprotein serine/threonine kinase activityInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0008024
all species →		Cellular Componentcyclin/CDK positive transcription elongation factor complexInterproscan
GO:0008353
all species →		Molecular FunctionRNA polymerase II CTD heptapeptide repeat kinase activityInterproscan
GO:0030332
all species →		Molecular Functioncyclin bindingInterproscan
GO:0032968
all species →		Biological Processpositive regulation of transcription elongation by RNA polymerase IIInterproscan
GO:0070816
all species →		Biological Processobsolete phosphorylation of RNA polymerase II C-terminal domainInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for g6367.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of g6367.t1 across 48 RNA-seq samples of Montipora capitata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
3Conditions
299.1Max TPM
118.2Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organisms · ambient pH treatment 21 21 115.93 272.14
whole organisms · low pH treatment 15 15 125.09 299.11
whole organisms · extra low pH treatment pH treatment 12 12 113.55 240.75

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR11452246 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 272.14
SRR11452252 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 263.25
SRR11452250 whole organisms · ambient pH treatment whole organisms prawn chip ambient pH treatment SRP254626 231.35
SRR11452259 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 159.80
SRR11452254 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 154.50
SRR11452251 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 131.91
SRR11452260 whole organisms · ambient pH treatment whole organisms cleavage ambient pH treatment SRP254626 126.53
SRR11452263 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 117.16
SRR11452234 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 105.22
SRR11452262 whole organisms · ambient pH treatment whole organisms egg ambient pH treatment SRP254626 101.28
SRR11452217 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 96.88
SRR11452243 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 91.49
SRR11452240 whole organisms · ambient pH treatment whole organisms fertilized embryo ambient pH treatment SRP254626 89.64
SRR11452233 whole organisms · ambient pH treatment whole organisms morula ambient pH treatment SRP254626 83.02
SRR11452242 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 71.72
SRR11452237 whole organisms · ambient pH treatment whole organisms gastrula ambient pH treatment SRP254626 69.52
SRR11452232 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 68.87
SRR11452230 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 55.35
SRR11452231 whole organisms · ambient pH treatment whole organisms blastula ambient pH treatment SRP254626 51.64
SRR11452228 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 49.12
SRR11452222 whole organisms · ambient pH treatment whole organisms planulae ambient pH treatment SRP254626 44.06
SRR11452245 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 299.11
SRR11452247 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 256.48
SRR11452249 whole organisms · low pH treatment whole organisms prawn chip low pH treatment SRP254626 223.70
SRR11452258 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 146.87
SRR11452229 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 127.15
SRR11452218 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 125.47
SRR11452253 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 117.55
SRR11452255 whole organisms · low pH treatment whole organisms cleavage low pH treatment SRP254626 115.65
SRR11452216 whole organisms · low pH treatment whole organisms fertilized embryo low pH treatment SRP254626 101.84
SRR11452236 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 84.50
SRR11452238 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 77.19
SRR11452241 whole organisms · low pH treatment whole organisms gastrula low pH treatment SRP254626 66.78
SRR11452224 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 46.38
SRR11452223 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 45.84
SRR11452221 whole organisms · low pH treatment whole organisms planulae low pH treatment SRP254626 41.89
SRR11452244 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 240.75
SRR11452248 whole organisms · extra low pH treatment pH treatment whole organisms prawn chip extra low pH treatment pH treatment SRP254626 233.10
SRR11452256 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 156.64
SRR11452257 whole organisms · extra low pH treatment pH treatment whole organisms cleavage extra low pH treatment pH treatment SRP254626 115.02
SRR11452261 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 109.04
SRR11452219 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 105.91
SRR11452220 whole organisms · extra low pH treatment pH treatment whole organisms fertilized embryo extra low pH treatment pH treatment SRP254626 98.53
SRR11452235 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 82.71
SRR11452239 whole organisms · extra low pH treatment pH treatment whole organisms gastrula extra low pH treatment pH treatment SRP254626 79.36
SRR11452225 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 50.84
SRR11452227 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 47.40
SRR11452226 whole organisms · extra low pH treatment pH treatment whole organisms planulae extra low pH treatment pH treatment SRP254626 43.28

Source: CnidoSite RNA-seq expression matrices (MCAPI_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capitata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated29g6838.t10.961226327048157
Negatively correlated3g6828.t1-0.827016500828135

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capitata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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