Gene detail

Detailed information of g653.t1 in Calvadosia cruxmelitensis

Genomic Location: not available for this species
NR annotation: XP_047139397.1, non-lysosomal glucosylceramidase [Hydra vulgaris]
Species Calvadosia cruxmelitensis · all data for this species · gene families

Sequence

Sequence data are not available for Calvadosia cruxmelitensis.
Nucleotide and protein sequences are provided for the species whose genome annotation is complete (see annotated genomes); for this species only the assembly is archived. The functional annotation below is likewise unavailable.

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5M868	Non-lysosomal glucosylceramidase OS=Rattus norvegicus OX=10116 GN=Gba2 PE=2 SV=2
Q9HCG7	Non-lysosomal glucosylceramidase OS=Homo sapiens OX=9606 GN=GBA2 PE=1 SV=2
Q69ZF3	Non-lysosomal glucosylceramidase OS=Mus musculus OX=10090 GN=Gba2 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000042 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000300 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000331 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0000629 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001260 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0001579 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0004526 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0007563 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0008396 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0009195 (this species only) · gene tree & orthology
Orthogroup (gene family)	OG0026062 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00264 all species →	Tyrosinase	Common central domain of tyrosinase	Domain	Interproscan
PF02574 all species →	S-methyl_trans	Homocysteine S-methyltransferase	Family	Interproscan
PF07281 all species →	INSIG	Insulin-induced protein (INSIG)	Family	Interproscan
PF04107 all species →	GCS2	Glutamate-cysteine ligase family 2(GCS2)	Family	Interproscan
PF02736 all species →	Myosin_N	Myosin N-terminal SH3-like domain	Domain	Interproscan
PF01576 all species →	Myosin_tail_1	Myosin tail	Coiled-coil	Interproscan
PF00063 all species →	Myosin_head	Myosin head (motor domain)	Domain	Interproscan
PF12215 all species →	Glyco_hydr_116N	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	Family	Interproscan
PF04685 all species →	DUF608	Glycosyl-hydrolase family 116, catalytic region	Repeat	Interproscan
PF00248 all species →	Aldo_ket_red	Aldo/keto reductase family	Domain	Interproscan
PF03137 all species →	OATP	Organic Anion Transporter Polypeptide (OATP) family	Family	Interproscan
PF00153 all species →	Mito_carr	Mitochondrial carrier protein	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002227 all species →	Domain	Tyrosinase copper-binding domain	Interproscan
IPR050316 all species →	Family	Tyrosinase and Hemocyanin	Interproscan
IPR008922 all species →	Homologous_superfamily	Di-copper centre-containing domain superfamily	Interproscan
IPR003726 all species →	Domain	Homocysteine-binding domain	Interproscan
IPR036589 all species →	Homologous_superfamily	Homocysteine-binding domain superfamily	Interproscan
IPR051524 all species →	Family	Betaine-homocysteine S-methyltransferase	Interproscan
IPR025929 all species →	Family	Insulin-induced protein family	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR001584 all species →	Domain	Integrase, catalytic core	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR035434 all species →	Family	Glutamate--cysteine ligase, bacteria and plant	Interproscan
IPR006336 all species →	Family	Glutamate--cysteine ligase, GCS2	Interproscan
IPR011556 all species →	Family	Glutamate--cysteine ligase, plant-type	Interproscan
IPR014746 all species →	Homologous_superfamily	Glutamine synthetase/guanido kinase, catalytic domain	Interproscan
IPR004009 all species →	Domain	Myosin, N-terminal, SH3-like	Interproscan
IPR001609 all species →	Domain	Myosin head, motor domain	Interproscan
IPR014751 all species →	Homologous_superfamily	DNA repair protein XRCC4-like, C-terminal	Interproscan
IPR000048 all species →	Binding_site	IQ motif, EF-hand binding site	Interproscan
IPR002928 all species →	Domain	Myosin tail	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR036961 all species →	Homologous_superfamily	Kinesin motor domain superfamily	Interproscan
IPR008989 all species →	Homologous_superfamily	Myosin S1 fragment, N-terminal	Interproscan
IPR008928 all species →	Homologous_superfamily	Six-hairpin glycosidase superfamily	Interproscan
IPR024462 all species →	Domain	Glycosyl-hydrolase family 116, N-terminal	Interproscan
IPR006775 all species →	Domain	Glycosyl-hydrolase family 116, catalytic region	Interproscan
IPR001627 all species →	Domain	Sema domain	Interproscan
IPR012341 all species →	Homologous_superfamily	Six-hairpin glycosidase-like superfamily	Interproscan
IPR052566 all species →	Family	Non-lysosomal glucosylceramidase	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR036352 all species →	Homologous_superfamily	Sema domain superfamily	Interproscan
IPR050523 all species →	Family	Aldo/Keto Reductase Detoxification and Biosynthesis	Interproscan
IPR036812 all species →	Homologous_superfamily	NADP-dependent oxidoreductase domain superfamily	Interproscan
IPR023210 all species →	Domain	NADP-dependent oxidoreductase domain	Interproscan
IPR036259 all species →	Homologous_superfamily	MFS transporter superfamily	Interproscan
IPR004156 all species →	Family	Organic anion transporter polypeptide	Interproscan
IPR023395 all species →	Homologous_superfamily	Mitochondrial carrier domain superfamily	Interproscan
IPR039158 all species →	Family	Solute carrier family 25 member 46	Interproscan
IPR018108 all species →	Repeat	Mitochondrial substrate/solute carrier	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11474 all species →	TYROSINASE FAMILY MEMBER	Interproscan
PTHR46120 all species →	BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1	Interproscan
PTHR15301 all species →	INSULIN-INDUCED GENE 1	Interproscan
PTHR42648 all species →	TRANSPOSASE, PUTATIVE-RELATED	Interproscan
PTHR34378 all species →	GLUTAMATE--CYSTEINE LIGASE, CHLOROPLASTIC	Interproscan
PTHR45615 all species →	MYOSIN HEAVY CHAIN, NON-MUSCLE	Interproscan
PTHR12654 all species →	BILE ACID BETA-GLUCOSIDASE-RELATED	Interproscan
PTHR43364 all species →	NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED	Interproscan
PTHR11388 all species →	ORGANIC ANION TRANSPORTER	Interproscan
PTHR21252 all species →	TB1 PROTEIN-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0009086 all species →	Biological Process	methionine biosynthetic process	Interproscan
GO:0047150 all species →	Molecular Function	betaine-homocysteine S-methyltransferase activity	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0016126 all species →	Biological Process	sterol biosynthetic process	Interproscan
GO:0015074 all species →	Biological Process	DNA integration	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0004357 all species →	Molecular Function	glutamate-cysteine ligase activity	Interproscan
GO:0006750 all species →	Biological Process	glutathione biosynthetic process	Interproscan
GO:0042398 all species →	Biological Process	modified amino acid biosynthetic process	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0003774 all species →	Molecular Function	cytoskeletal motor activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0016459 all species →	Cellular Component	myosin complex	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0000146 all species →	Molecular Function	microfilament motor activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0016460 all species →	Cellular Component	myosin II complex	Interproscan
GO:0032982 all species →	Cellular Component	myosin filament	Interproscan
GO:0051015 all species →	Molecular Function	actin filament binding	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0004553 all species →	Molecular Function	hydrolase activity, hydrolyzing O-glycosyl compounds	Interproscan
GO:0008422 all species →	Molecular Function	beta-glucosidase activity	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0055085 all species →	Biological Process	transmembrane transport	Interproscan
GO:0000266 all species →	Biological Process	mitochondrial fission	Interproscan
GO:0005741 all species →	Cellular Component	mitochondrial outer membrane	Interproscan
GO:0090149 all species →	Biological Process	mitochondrial membrane fission	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00544	BHMT; betaine-homocysteine S-methyltransferase	EC:2.1.1.5	Cysteine and methionine metabolism	ko00270	deepkoala
K01064	WNT9; wingless-type MMTV integration site family, member 9	-	Glycosaminoglycan binding proteins	ko00536	deepkoala
K03454	SLC25A46; solute carrier family 25, member 46	-	Transporters	ko02000	deepkoala
K17751	MYH6_7; myosin heavy chain 6/7	-	Cytoskeleton proteins	ko04812	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Calvadosia cruxmelitensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Calvadosia cruxmelitensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	sequence table not available	–
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	sequence table not available	–
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →