Genomic Location: :...
NR annotation: XP_047129174.1, protein dopey-1 [Hydra vulgaris]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q5JWR5 | Protein DOP1A OS=Homo sapiens OX=9606 GN=DOP1A PE=1 SV=1 | ||||
| A1ZBE8 | Protein DOP1 homolog OS=Drosophila melanogaster OX=7227 GN=CG15099 PE=1 SV=1 | ||||
| Q292H2 | Protein DOP1 homolog OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=GA13490 PE=3 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity RING|RING |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01250 | Ribosomal_S6 | Ribosomal protein S6 | Domain | Interproscan |
| PF01866 | Diphthamide_syn | Putative diphthamide synthesis protein | Family | Interproscan |
| PF00571 | CBS | CBS domain | Domain | Interproscan |
| PF03471 | CorC_HlyC | Transporter associated domain | Domain | Interproscan |
| PF00579 | tRNA-synt_1b | tRNA synthetases class I (W and Y) | Family | Interproscan |
| PF02762 | Cbl_N3 | CBL proto-oncogene N-terminus, SH2-like domain | Domain | Interproscan |
| PF02262 | Cbl_N | CBL proto-oncogene N-terminal domain 1 | Domain | Interproscan |
| PF13920 | zf-C3HC4_3 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF02761 | Cbl_N2 | CBL proto-oncogene N-terminus, EF hand-like domain | Domain | Interproscan |
| PF00616 | RasGAP | GTPase-activator protein for Ras-like GTPase | Family | Interproscan |
| PF00612 | IQ | IQ calmodulin-binding motif | Motif | Interproscan |
| PF21788 | TNP-like_GBD | TNP-like, GTP-binding insertion domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000529 | Family | Small ribosomal subunit protein bS6 | Interproscan |
| IPR035980 | Homologous_superfamily | Small ribosomal subunit protein bS6 superfamily | Interproscan |
| IPR014717 | Homologous_superfamily | Translation elongation factor EF1B/small ribosomal subunit protein bS6 | Interproscan |
| IPR020814 | Family | Small ribosomal subunit protein bS6, plastid/chloroplast | Interproscan |
| IPR042265 | Homologous_superfamily | Diphthamide synthesis DPH1/DPH2, domain 3 | Interproscan |
| IPR016435 | Family | Diphthamide synthesis DPH1/DPH2 | Interproscan |
| IPR040314 | Family | Protein dopey | Interproscan |
| IPR005170 | Domain | Transporter-associated domain | Interproscan |
| IPR046342 | Homologous_superfamily | CBS domain superfamily | Interproscan |
| IPR016169 | Homologous_superfamily | FAD-binding, type PCMH, subdomain 2 | Interproscan |
| IPR000644 | Domain | CBS domain | Interproscan |
| IPR036318 | Homologous_superfamily | FAD-binding, type PCMH-like superfamily | Interproscan |
| IPR044751 | Domain | Ion transporter-like, CBS domain | Interproscan |
| IPR002307 | Family | Tyrosine-tRNA ligase | Interproscan |
| IPR002305 | Family | Aminoacyl-tRNA synthetase, class Ic | Interproscan |
| IPR014729 | Homologous_superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Interproscan |
| IPR036986 | Homologous_superfamily | RNA-binding S4 domain superfamily | Interproscan |
| IPR024088 | Family | Tyrosine-tRNA ligase, bacterial-type | Interproscan |
| IPR014742 | Domain | Adaptor protein Cbl, SH2-like domain | Interproscan |
| IPR003153 | Domain | Adaptor protein Cbl, N-terminal helical | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR036860 | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR036537 | Homologous_superfamily | Adaptor protein Cbl, N-terminal domain superfamily | Interproscan |
| IPR024159 | Domain | Adaptor protein Cbl, PTB domain | Interproscan |
| IPR024162 | Family | Adaptor protein Cbl | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR014741 | Domain | Adaptor protein Cbl, EF hand-like | Interproscan |
| IPR015940 | Domain | Ubiquitin-associated domain | Interproscan |
| IPR009060 | Homologous_superfamily | UBA-like superfamily | Interproscan |
| IPR017907 | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR001936 | Domain | Ras GTPase-activating domain | Interproscan |
| IPR023152 | Conserved_site | Ras GTPase-activating protein, conserved site | Interproscan |
| IPR008936 | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR000048 | Binding_site | IQ motif, EF-hand binding site | Interproscan |
| IPR048366 | Domain | Transposable element P transposase-like, GTP-binding insertion domain | Interproscan |
| IPR028750 | Family | Centrosome-associated protein 350/Coiled-coil domain-containing protein 187 | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21011 | MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 | Interproscan |
| PTHR10762 | DIPHTHAMIDE BIOSYNTHESIS PROTEIN | Interproscan |
| PTHR14042 | DOPEY-RELATED | Interproscan |
| PTHR22777 | HEMOLYSIN-RELATED | Interproscan |
| PTHR11766 | TYROSYL-TRNA SYNTHETASE | Interproscan |
| PTHR23007 | CBL | Interproscan |
| PTHR14149 | RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF | Interproscan |
| PTHR13958 | CENTROSOME-ASSOCIATED PROTEIN 350 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003735 | Molecular Function | structural constituent of ribosome | Interproscan |
| GO:0005840 | Cellular Component | ribosome | Interproscan |
| GO:0006412 | Biological Process | translation | Interproscan |
| GO:0019843 | Molecular Function | rRNA binding | Interproscan |
| GO:0015935 | Cellular Component | small ribosomal subunit | Interproscan |
| GO:0022627 | Cellular Component | cytosolic small ribosomal subunit | Interproscan |
| GO:0070181 | Molecular Function | small ribosomal subunit rRNA binding | Interproscan |
| GO:0017183 | Biological Process | protein histidyl modification to diphthamide | Interproscan |
| GO:0090560 | Molecular Function | 2-(3-amino-3-carboxypropyl)histidine synthase activity | Interproscan |
| GO:0005768 | Cellular Component | endosome | Interproscan |
| GO:0005802 | Cellular Component | trans-Golgi network | Interproscan |
| GO:0006895 | Biological Process | Golgi to endosome transport | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0004831 | Molecular Function | tyrosine-tRNA ligase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006437 | Biological Process | tyrosyl-tRNA aminoacylation | Interproscan |
| GO:0004812 | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0006418 | Biological Process | tRNA aminoacylation for protein translation | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0043039 | Biological Process | tRNA aminoacylation | Interproscan |
| GO:0007166 | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0001784 | Molecular Function | phosphotyrosine residue binding | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0007175 | Biological Process | negative regulation of epidermal growth factor-activated receptor activity | Interproscan |
| GO:0017124 | Molecular Function | SH3 domain binding | Interproscan |
| GO:0023051 | Biological Process | regulation of signaling | Interproscan |
| GO:0030971 | Molecular Function | receptor tyrosine kinase binding | Interproscan |
| GO:0045121 | Cellular Component | membrane raft | Interproscan |
| GO:0061630 | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0043087 | Biological Process | regulation of GTPase activity | Interproscan |
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005516 | Molecular Function | calmodulin binding | Interproscan |
| GO:0005938 | Cellular Component | cell cortex | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:1903479 | Biological Process | mitotic actomyosin contractile ring assembly actin filament organization | Interproscan |
| GO:0005813 | Cellular Component | centrosome | Interproscan |
| GO:0008017 | Molecular Function | microtubule binding | Interproscan |
| GO:0034453 | Biological Process | microtubule anchoring | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K02990 | RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 | - | Membrane trafficking | ko04131 | deepkoala |
| Mitochondrial biogenesis | ko03029 | deepkoala | |||
| Ribosome | ko03011 | deepkoala |