Genomic Location: :...
NR annotation: XP_020907207.1, serine/threonine-protein kinase WNK4 isoform X1 [Exaiptasia diaphana]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description |
|---|---|
| Q9JIH7 | Serine/threonine-protein kinase WNK1 OS=Rattus norvegicus OX=10116 GN=Wnk1 PE=1 SV=2 |
| Q9H4A3 | Serine/threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 |
| Q6R2V0 | Serine/threonine-protein kinase WNK1 OS=Sus scrofa OX=9823 GN=WNK1 PE=2 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07657 | MNNL | N terminus of Notch ligand C2-like domain | Domain | Interproscan |
| PF00160 | Pro_isomerase | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | Domain | Interproscan |
| PF05192 | MutS_III | MutS domain III | Domain | Interproscan |
| PF05188 | MutS_II | MutS domain II | Domain | Interproscan |
| PF17862 | AAA_lid_3 | AAA+ lid domain | Domain | Interproscan |
| PF00004 | AAA | ATPase family associated with various cellular activities (AAA) | Domain | Interproscan |
| PF12202 | OSR1_C | Oxidative-stress-responsive kinase 1 C-terminal domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011651 | Domain | Notch ligand, N-terminal domain | Interproscan |
| IPR029000 | Homologous_superfamily | Cyclophilin-like domain superfamily | Interproscan |
| IPR002130 | Domain | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | Interproscan |
| IPR035542 | Family | Cyclophilin-RNA interacting protein | Interproscan |
| IPR036187 | Homologous_superfamily | DNA mismatch repair protein MutS, core domain superfamily | Interproscan |
| IPR036678 | Homologous_superfamily | MutS, connector domain superfamily | Interproscan |
| IPR007696 | Domain | DNA mismatch repair protein MutS, core | Interproscan |
| IPR007860 | Domain | DNA mismatch repair protein MutS, connector domain | Interproscan |
| IPR045076 | Family | DNA mismatch repair MutS family | Interproscan |
| IPR050221 | Family | 26S Proteasome Regulatory ATPase | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR003960 | Conserved_site | ATPase, AAA-type, conserved site | Interproscan |
| IPR041569 | Domain | AAA ATPase, AAA+ lid domain | Interproscan |
| IPR003959 | Domain | ATPase, AAA-type, core | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR050588 | Family | With No Lysine (K) Ser/Thr Protein Kinase | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR024678 | Domain | Serine/threonine-protein kinase OSR1/WNK, CCT domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23159 | CENTROSOMAL PROTEIN 2 | Interproscan |
| PTHR45843 | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 | Interproscan |
| PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | Interproscan |
| PTHR23073 | 26S PROTEASOME REGULATORY SUBUNIT | Interproscan |
| PTHR13902 | SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0007219 | Biological Process | Notch signaling pathway | Interproscan |
| GO:0007275 | Biological Process | multicellular organism development | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0000413 | Biological Process | protein peptidyl-prolyl isomerization | Interproscan |
| GO:0003755 | Molecular Function | peptidyl-prolyl cis-trans isomerase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006298 | Biological Process | mismatch repair | Interproscan |
| GO:0030983 | Molecular Function | mismatched DNA binding | Interproscan |
| GO:0003690 | Molecular Function | double-stranded DNA binding | Interproscan |
| GO:0006312 | Biological Process | mitotic recombination | Interproscan |
| GO:0032301 | Cellular Component | MutSalpha complex | Interproscan |
| GO:0140664 | Molecular Function | ATP-dependent DNA damage sensor activity | Interproscan |
| GO:0008540 | Cellular Component | proteasome regulatory particle, base subcomplex | Interproscan |
| GO:0036402 | Molecular Function | proteasome-activating activity | Interproscan |
| GO:0043161 | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K08867 | WNK, PRKWNK; WNK lysine deficient protein kinase | EC:2.7.11.1 | Protein phosphatases and associated proteins | ko01009 | deepkoala |