Gene detail

Detailed information of g7138.t1.1 in Nemopilema nomurai

Genomic Location: :...
NR annotation: XP_020622595.1, uncharacterized protein LOC110060183 [Orbicella faveolata]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q8IS14	Ras guanine nucleotide exchange factor J OS=Dictyostelium discoideum OX=44689 GN=gefJ PE=2 SV=1
O14827	Ras-specific guanine nucleotide-releasing factor 2 OS=Homo sapiens OX=9606 GN=RASGRF2 PE=1 SV=2
Q8IS15	Ras guanine nucleotide exchange factor I OS=Dictyostelium discoideum OX=44689 GN=gefI PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00617	RasGEF	RasGEF domain	Family	Interproscan
PF12796	Ank_2	Ankyrin repeats (3 copies)	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036964	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan
IPR011989	Homologous_superfamily	Armadillo-like helical	Interproscan
IPR036770	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	Interproscan
IPR001895	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR011993	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR016024	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR002110	Repeat	Ankyrin repeat	Interproscan
IPR008937	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR000651	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR023578	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005085	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0007265	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547	Biological Process	positive regulation of GTPase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K08018	RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2	-	Tight junction	ko04530	deepkoala