Genomic Location: :...
NR annotation: XP_035676777.1, RNA helicase aquarius-like [Branchiostoma floridae]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| O60306 | RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 | ||||
| Q8CFQ3 | RNA helicase aquarius OS=Mus musculus OX=10090 GN=Aqr PE=1 SV=2 | ||||
| O94508 | Pre-mRNA-splicing factor cwf11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cwf11 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Transcription Factors Family | bHLH |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21144 | Aquarius_N_3rd | Intron-binding protein aquarius insert domain | Domain | Interproscan |
| PF13086 | AAA_11 | AAA domain | Domain | Interproscan |
| PF21143 | Aquarius_N_2nd | Intron-binding protein aquarius, beta-barrel | Domain | Interproscan |
| PF16399 | Aquarius_N_1st | Intron-binding protein aquarius N-terminal | Repeat | Interproscan |
| PF13087 | AAA_12 | AAA domain | Domain | Interproscan |
| PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain | Family | Interproscan |
| PF02932 | Neur_chan_memb | Neurotransmitter-gated ion-channel transmembrane region | Family | Interproscan |
| PF10591 | SPARC_Ca_bdg | Secreted protein acidic and rich in cysteine Ca binding region | Domain | Interproscan |
| PF07647 | SAM_2 | SAM domain (Sterile alpha motif) | Domain | Interproscan |
| PF12736 | CABIT | Cell-cycle sustaining, positive selection, | Domain | Interproscan |
| PF17814 | LisH_TPL | LisH-like dimerisation domain | Domain | Interproscan |
| PF00010 | HLH | Helix-loop-helix DNA-binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR047187 | Domain | Upf1-like, C-terminal helicase domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR048967 | Domain | RNA helicase aquarius, insertion domain | Interproscan |
| IPR041677 | Domain | DNA2/NAM7 helicase, helicase domain | Interproscan |
| IPR045055 | Family | DNA2/NAM7-like helicase | Interproscan |
| IPR048966 | Domain | RNA helicase aquarius, beta-barrel | Interproscan |
| IPR032174 | Domain | RNA helicase aquarius, N-terminal domain | Interproscan |
| IPR026300 | Family | CWF11 family | Interproscan |
| IPR041679 | Domain | DNA2/NAM7 helicase-like, C-terminal | Interproscan |
| IPR006201 | Family | Neurotransmitter-gated ion-channel | Interproscan |
| IPR018000 | Conserved_site | Neurotransmitter-gated ion-channel, conserved site | Interproscan |
| IPR038050 | Homologous_superfamily | Neuronal acetylcholine receptor | Interproscan |
| IPR002394 | Family | Nicotinic acetylcholine receptor | Interproscan |
| IPR006202 | Domain | Neurotransmitter-gated ion-channel ligand-binding domain | Interproscan |
| IPR036719 | Homologous_superfamily | Neurotransmitter-gated ion-channel transmembrane domain superfamily | Interproscan |
| IPR006029 | Domain | Neurotransmitter-gated ion-channel transmembrane domain | Interproscan |
| IPR036734 | Homologous_superfamily | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR019577 | Domain | SPARC/Testican, calcium-binding domain | Interproscan |
| IPR001660 | Domain | Sterile alpha motif domain | Interproscan |
| IPR013761 | Homologous_superfamily | Sterile alpha motif/pointed domain superfamily | Interproscan |
| IPR025946 | Domain | CABIT domain | Interproscan |
| IPR050951 | Family | Retrovirus-related Pol polyprotein | Interproscan |
| IPR040067 | Family | WD repeat-containing protein 47 | Interproscan |
| IPR006595 | Domain | CTLH, C-terminal LisH motif | Interproscan |
| IPR006594 | Conserved_site | LIS1 homology motif | Interproscan |
| IPR011598 | Domain | Myc-type, basic helix-loop-helix (bHLH) domain | Interproscan |
| IPR036638 | Homologous_superfamily | Helix-loop-helix DNA-binding domain superfamily | Interproscan |
| IPR050433 | Family | Myc family transcription factors | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10887 | DNA2/NAM7 HELICASE FAMILY | Interproscan |
| PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | Interproscan |
| PTHR37984 | PROTEIN CBG26694 | Interproscan |
| PTHR19863 | NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG | Interproscan |
| PTHR45851 | MYC PROTO-ONCOGENE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004386 | Molecular Function | helicase activity | Interproscan |
| GO:0003729 | Molecular Function | mRNA binding | Interproscan |
| GO:0071013 | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0000398 | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0005681 | Cellular Component | spliceosomal complex | Interproscan |
| GO:0004888 | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| GO:0005216 | Molecular Function | monoatomic ion channel activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0034220 | Biological Process | monoatomic ion transmembrane transport | Interproscan |
| GO:0005231 | Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0007268 | Biological Process | chemical synaptic transmission | Interproscan |
| GO:0030594 | Molecular Function | neurotransmitter receptor activity | Interproscan |
| GO:0042391 | Biological Process | regulation of membrane potential | Interproscan |
| GO:0043005 | Cellular Component | neuron projection | Interproscan |
| GO:0045202 | Cellular Component | synapse | Interproscan |
| GO:0050877 | Biological Process | nervous system process | Interproscan |
| GO:1904315 | Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Interproscan |
| GO:0006811 | Biological Process | monoatomic ion transport | Interproscan |
| GO:0022848 | Molecular Function | acetylcholine-gated monoatomic cation-selective channel activity | Interproscan |
| GO:0045211 | Cellular Component | postsynaptic membrane | Interproscan |
| GO:0005230 | Molecular Function | extracellular ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0000981 | Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | Interproscan |
| GO:0006357 | Biological Process | regulation of transcription by RNA polymerase II | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04377 | MYC; Myc proto-oncogene protein | - | Spliceosome | ko03041 | deepkoala |
| Messenger RNA biogenesis | ko03019 | deepkoala |