Genomic Location: :...
NR annotation: MCG8335096.1, serine hydroxymethyltransferase [Pseudomonadota bacterium]
| CDS | |||||
| Transcript |
| Protein |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| C6E348 | Serine hydroxymethyltransferase OS=Geobacter sp. (strain M21) OX=443144 GN=glyA PE=3 SV=1 | ||||
| B5E8U0 | Serine hydroxymethyltransferase OS=Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem) OX=404380 GN=glyA PE=3 SV=1 | ||||
| B8J189 | Serine hydroxymethyltransferase OS=Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB) OX=525146 GN=glyA PE=3 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | DUB|OTU|OTU |
| Ubiquitin Family | DUB|ULP|ULP |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06244 | Ccdc124 | Coiled-coil domain-containing protein 124 /Oxs1 | Family | Interproscan |
| PF00464 | SHMT | Serine hydroxymethyltransferase | Domain | Interproscan |
| PF02502 | LacAB_rpiB | Ribose/Galactose Isomerase | Family | Interproscan |
| PF02902 | Peptidase_C48 | Ulp1 protease family, C-terminal catalytic domain | Domain | Interproscan |
| PF10444 | Nbl1_Borealin_N | Nbl1 / Borealin N terminal | Family | Interproscan |
| PF02338 | OTU | OTU-like cysteine protease | Family | Interproscan |
| PF00514 | Arm | Armadillo/beta-catenin-like repeat | Repeat | Interproscan |
| PF08385 | DHC_N1 | Dynein heavy chain, N-terminal region 1 | Family | Interproscan |
| PF08393 | DHC_N2 | Dynein heavy chain, N-terminal region 2 | Family | Interproscan |
| PF12774 | AAA_6 | Hydrolytic ATP binding site of dynein motor region | Domain | Interproscan |
| PF12775 | AAA_7 | P-loop containing dynein motor region | Domain | Interproscan |
| PF17852 | Dynein_AAA_lid | Dynein heavy chain AAA lid domain | Domain | Interproscan |
| PF00665 | rve | Integrase core domain | Domain | Interproscan |
| PF13976 | gag_pre-integrs | GAG-pre-integrase domain | Domain | Interproscan |
| PF00078 | RVT_1 | Reverse transcriptase (RNA-dependent DNA polymerase) | Domain | Interproscan |
| PF01699 | Na_Ca_ex | Sodium/calcium exchanger protein | Family | Interproscan |
| PF13843 | DDE_Tnp_1_7 | Transposase IS4 | Domain | Interproscan |
| PF00168 | C2 | C2 domain | Domain | Interproscan |
| PF06292 | MUN | MUN domain | Repeat | Interproscan |
| PF00153 | Mito_carr | Mitochondrial carrier protein | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR010422 | Family | Coiled-coil domain-containing protein 124/Oxs1 | Interproscan |
| IPR036910 | Homologous_superfamily | High mobility group box domain superfamily | Interproscan |
| IPR036569 | Homologous_superfamily | Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily | Interproscan |
| IPR001085 | Family | Serine hydroxymethyltransferase | Interproscan |
| IPR039429 | Domain | Serine hydroxymethyltransferase-like domain | Interproscan |
| IPR049943 | Family | Serine hydroxymethyltransferase-like | Interproscan |
| IPR015424 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase | Interproscan |
| IPR015421 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, major domain | Interproscan |
| IPR019798 | Binding_site | Serine hydroxymethyltransferase, pyridoxal phosphate binding site | Interproscan |
| IPR003500 | Family | Sugar-phosphate isomerase, RpiB/LacA/LacB family | Interproscan |
| IPR015422 | Homologous_superfamily | Pyridoxal phosphate-dependent transferase, small domain | Interproscan |
| IPR038765 | Homologous_superfamily | Papain-like cysteine peptidase superfamily | Interproscan |
| IPR003653 | Domain | Ulp1 protease family, C-terminal catalytic domain | Interproscan |
| IPR018851 | Domain | Borealin, N-terminal | Interproscan |
| IPR018867 | Family | Cell division protein borealin | Interproscan |
| IPR003323 | Domain | OTU domain | Interproscan |
| IPR050704 | Family | OTU domain-containing ubiquitin thioesterase | Interproscan |
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR000225 | Repeat | Armadillo | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR013594 | Domain | Dynein heavy chain, tail | Interproscan |
| IPR042228 | Homologous_superfamily | Dynein heavy chain, linker, subdomain 3 | Interproscan |
| IPR026983 | Family | Dynein heavy chain | Interproscan |
| IPR013602 | Domain | Dynein heavy chain, linker | Interproscan |
| IPR035699 | Domain | Dynein heavy chain, hydrolytic ATP-binding dynein motor region | Interproscan |
| IPR042222 | Homologous_superfamily | Dynein heavy chain, domain 2, N-terminal | Interproscan |
| IPR003593 | Domain | AAA+ ATPase domain | Interproscan |
| IPR041466 | Domain | Dynein heavy chain, AAA 5 extension domain | Interproscan |
| IPR043157 | Homologous_superfamily | Dynein heavy chain, AAA1 domain, small subdomain | Interproscan |
| IPR001584 | Domain | Integrase, catalytic core | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR025724 | Domain | GAG-pre-integrase domain | Interproscan |
| IPR043502 | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR000477 | Domain | Reverse transcriptase domain | Interproscan |
| IPR044880 | Homologous_superfamily | NCX, central ion-binding domain superfamily | Interproscan |
| IPR051171 | Family | Calcium/Cation Antiporter | Interproscan |
| IPR004837 | Domain | Sodium/calcium exchanger membrane region | Interproscan |
| IPR029526 | Domain | PiggyBac transposable element-derived protein | Interproscan |
| IPR014770 | Domain | Munc13 homology 1 | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR052095 | Family | UNC-13 domain-containing protein | Interproscan |
| IPR014772 | Domain | Mammalian uncoordinated homology 13, domain 2 | Interproscan |
| IPR000008 | Domain | C2 domain | Interproscan |
| IPR010439 | Domain | MUN domain | Interproscan |
| IPR018108 | Repeat | Mitochondrial substrate/solute carrier | Interproscan |
| IPR023395 | Homologous_superfamily | Mitochondrial carrier domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21680 | UNCHARACTERIZED | Interproscan |
| PTHR11680 | SERINE HYDROXYMETHYLTRANSFERASE | Interproscan |
| PTHR12606 | SENTRIN/SUMO-SPECIFIC PROTEASE | Interproscan |
| PTHR16040 | AUSTRALIN, ISOFORM A-RELATED | Interproscan |
| PTHR12419 | OTU DOMAIN CONTAINING PROTEIN | Interproscan |
| PTHR23314 | SPERM-ASSOCIATED ANTIGEN 6 ARMADILLO REPEAT-CONTAINING | Interproscan |
| PTHR46532 | MALE FERTILITY FACTOR KL5 | Interproscan |
| PTHR42648 | TRANSPOSASE, PUTATIVE-RELATED | Interproscan |
| PTHR47027 | REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN | Interproscan |
| PTHR11878 | SODIUM/CALCIUM EXCHANGER | Interproscan |
| PTHR46599 | PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 | Interproscan |
| PTHR45999 | UNC-13-4A, ISOFORM B | Interproscan |
| PTHR46181 | MITOCHONDRIAL GLYCINE TRANSPORTER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003713 | Molecular Function | transcription coactivator activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006366 | Biological Process | transcription by RNA polymerase II | Interproscan |
| GO:0005975 | Biological Process | carbohydrate metabolic process | Interproscan |
| GO:0016853 | Molecular Function | isomerase activity | Interproscan |
| GO:0004372 | Molecular Function | glycine hydroxymethyltransferase activity | Interproscan |
| GO:0019264 | Biological Process | glycine biosynthetic process from serine | Interproscan |
| GO:0030170 | Molecular Function | pyridoxal phosphate binding | Interproscan |
| GO:0035999 | Biological Process | tetrahydrofolate interconversion | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006565 | Biological Process | L-serine catabolic process | Interproscan |
| GO:0006730 | Biological Process | one-carbon metabolic process | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0046653 | Biological Process | tetrahydrofolate metabolic process | Interproscan |
| GO:0046655 | Biological Process | folic acid metabolic process | Interproscan |
| GO:0050897 | Molecular Function | cobalt ion binding | Interproscan |
| GO:0070905 | Molecular Function | serine binding | Interproscan |
| GO:0016926 | Biological Process | protein desumoylation | Interproscan |
| GO:0016929 | Molecular Function | deSUMOylase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0008234 | Molecular Function | cysteine-type peptidase activity | Interproscan |
| GO:0000070 | Biological Process | mitotic sister chromatid segregation | Interproscan |
| GO:0000775 | Cellular Component | chromosome, centromeric region | Interproscan |
| GO:0032133 | Cellular Component | chromosome passenger complex | Interproscan |
| GO:0051233 | Cellular Component | spindle midzone | Interproscan |
| GO:0004843 | Molecular Function | cysteine-type deubiquitinase activity | Interproscan |
| GO:0016579 | Biological Process | protein deubiquitination | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003341 | Biological Process | cilium movement | Interproscan |
| GO:0008017 | Molecular Function | microtubule binding | Interproscan |
| GO:0015630 | Cellular Component | microtubule cytoskeleton | Interproscan |
| GO:0005858 | Cellular Component | axonemal dynein complex | Interproscan |
| GO:0007018 | Biological Process | microtubule-based movement | Interproscan |
| GO:0030286 | Cellular Component | dynein complex | Interproscan |
| GO:0045505 | Molecular Function | dynein intermediate chain binding | Interproscan |
| GO:0051959 | Molecular Function | dynein light intermediate chain binding | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0016887 | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0015074 | Biological Process | DNA integration | Interproscan |
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0005432 | Molecular Function | calcium:sodium antiporter activity | Interproscan |
| GO:0005887 | Cellular Component | plasma membrane | Interproscan |
| GO:0015491 | Molecular Function | obsolete cation:cation antiporter activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0030001 | Biological Process | metal ion transport | Interproscan |
| GO:0030424 | Cellular Component | axon | Interproscan |
| GO:0035725 | Biological Process | sodium ion transmembrane transport | Interproscan |
| GO:0042383 | Cellular Component | sarcolemma | Interproscan |
| GO:0098703 | Biological Process | calcium ion import across plasma membrane | Interproscan |
| GO:0098794 | Cellular Component | postsynapse | Interproscan |
| GO:0055085 | Biological Process | transmembrane transport | Interproscan |
| GO:0099503 | Cellular Component | secretory vesicle | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0015187 | Molecular Function | glycine transmembrane transporter activity | Interproscan |
| GO:1904983 | Biological Process | glycine import into mitochondrion | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12655 | OTUD5, DUBA; OTU domain-containing protein 5 | EC:3.4.19.12 | Antifolate resistance | ko01523 | deepkoala |
| Cytoskeleton proteins | ko04812 | deepkoala | |||
| Cilium and associated proteins | ko03037 | deepkoala | |||
| Chromosome and associated proteins | ko03036 | deepkoala | |||
| Ubiquitin system | ko04121 | deepkoala |